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Levodopa–Benserazide

Published online by Cambridge University Press:  20 February 2025

K. Ray Chaudhuri ,
Peter Jenner ,
Valentina Leta ,
Shelley Jones  and
Iro Boura
K. Ray Chaudhuri
Affiliation:
King's College London
Peter Jenner
Affiliation:
King's College London
Valentina Leta
Affiliation:
King's College London
Shelley Jones
Affiliation:
King's College London
Iro Boura
Affiliation:
St. George General Hospital of Chania, Crete, Greece
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Summary

Levodopa ((–)-3,4-dihydroxyphenyl)-l-alanine) has a molecular weight of 197.19 and a molecular formula of C9H11NO4.

Benserazide hydrochloride ((RS)-2-amino-3-hydroxy-N′-(2,3,4-trihydroxybenzyl)propanehydrazide hydrochloride) has a molecular weight of 293.7 and a molecular formula of C10H16ClN3O5.

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Chapter
Information
The Movement Disorders Prescriber's Guide to Parkinson's Disease , pp. 183 - 190
Publisher: Cambridge University Press
Print publication year: 2025

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References

Suggested Reading

Tambasco, N, Romoli, M, Calabresi, P. Levodopa in Parkinson’s disease: current status and future developments. Curr Neuropharmacol 2018; 16(8): 1239–1252. doi: 10.2174/1570159X15666170510143821. PMID: 28494719; PMCID: PMC6187751.CrossRefGoogle Scholar

References

Co-beneldopa. In: Brayfield, A (Ed.), Martindale: The Complete Drug Reference. London: The Royal Pharmaceutical Society of Great Britain. Accessed on 30 October 2022 via www.medicinescomplete.com.Google Scholar
Joint Formulary Committee. British National Formulary (online). London: BMJ Group and Pharmaceutical Press. Accessed on 30 October 2022 via www.medicinescomplete.com.Google Scholar
Koschel, J, Ray Chaudhuri, K, Tönges, L, Thiel, M, Raeder, V, Jost, WH. Implications of dopaminergic medication withdrawal in Parkinson’s disease. J Neural Transm (Vienna) 2022; 129(9): 1169–1178.CrossRefGoogle Scholar
Summary of product characteristics – Madopar 100 mg/25 mg hard capsules. Roche Products Ltd. Electronic Medicines Compendium: Madopar 100 mg/25 mg hard capsules – summary of product characteristics (SmPC) – (emc). Accessed on 30 October 2022 via www.medicines.org.uk.Google Scholar

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