Skip to main content Accessibility help
×
Hostname: page-component-78c5997874-dh8gc Total loading time: 0 Render date: 2024-11-06T12:45:03.597Z Has data issue: false hasContentIssue false

7 - Parenteral drug administration

Published online by Cambridge University Press:  22 January 2010

Molly Courtenay
Affiliation:
University of Surrey
Matt Griffiths
Affiliation:
University of the West of England, Bristol
Get access

Summary

Introduction

Parenteral drug administration refers to drugs given by routes other than the digestive tract. The term parenteral is usually used for drugs given by injection or infusion. The enteral route usually refers to taking drugs by mouth. The common parenteral routes are listed in Table 7.1. In the USA the Food and Drug Administration (FDA) lists over 100 routes of drug administration (www.fda.gov/cder/dsm/).

Most hospital patients receive parenteral drugs at some time during their stay. Parenteral drug use is also increasingly common in the community setting (O'Hanlon, 2008). The intravenous (IV) route is associated with errors in several stages of the medication process (prescribing, preparing and administration) and this route has been associated with a higher number of errors than any other route (Hunt & Rapp, 1996; Cousins et al., 2005).

In one hospital ward study, there was at least one error made during preparation and administration in 212 (49%) out of 430 intravenous drug doses (Taxis & Barber, 2003). It is therefore important to only give drugs parenterally if it is not possible to use the simpler oral route – it is essential that the medication prescription is reviewed regularly and drug treatments changed to the safer oral route at the earliest opportunity.

Type
Chapter
Information
Medication Safety
An Essential Guide
, pp. 97 - 112
Publisher: Cambridge University Press
Print publication year: 2009

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Artinyan, A, Nunoo-Mensah, Balasubramaniam, JWS, et al. (2008). Prolonged postoperative ileus-definition, risk factors, and ‘predictors after surgery’. World Journal of Surgery, 32(7), 1495–500.CrossRefGoogle Scholar
Costello, J, Nyatanga, B, Mula, C, Hull, J. (2008). The benefits and drawbacks of syringe drivers in palliative care. International J Palliative Nursing, 14(3), 139–44.CrossRefGoogle ScholarPubMed
Cousins, DH, Sabatier, B, Begue, D, Schmittownal, AC, Hope-Tichy, T. (2005). Medication errors in intravenous drug preparation and administration: a multicentre audit in the UK, Germany and France. Quality and Safety in Health Care, 14(3), 190–5.CrossRefGoogle ScholarPubMed
Cowl, CT, Weinstock, JV, Al-Jurf, A, Ephgrave, K, Murray, JA, Dillon, K. (2000). Complications and cost associated with parenteral nutrition delivered to hospitalized patients through either subclavian or peripherally-inserted central catheters. Clinical Nutrition, 19(4), 237–43.CrossRefGoogle ScholarPubMed
,Department of Health UK, Immunisation Against Infectious Disease. 2006.
Donald, AI, Chinthamuneedi, MP, Spearritt, D. (2007). Effect of changes in syringe driver height on flow: a small quantitative study. Critical Care Resusc, 9(2), 143–7.Google ScholarPubMed
Gabriel, J. (2008a). Infusion therapy. Part 1: Minimising the risks. Nursing Standard, 22(31), 51–6; quiz 58.CrossRefGoogle Scholar
Gabriel, J. (2008b). Infusion therapy. Part 2: Prevention and management of complications. Nursing Standard, 22(32), 41–8; quiz 50.CrossRefGoogle Scholar
Gilbert, RE, Harden, M. (2008). Effectiveness of impregnated central venous catheters for catheter related blood stream infection: a systematic review. Current Opinion in Infectious Diseases, 21(3), 235–45.CrossRefGoogle ScholarPubMed
Hadaway, L. (2007). Infiltration and extravasation. American Journal of Nursing, 107(8), 64–72.CrossRefGoogle ScholarPubMed
Hunt, ML, Jr, Rapp, RP. (1996). Intravenous medication errors. Journal of Intravenous Nursing, 19(3 Suppl), S9–15.Google ScholarPubMed
Kenagy, JW, Stein, GC. (2001). Naming, labeling, and packaging of pharmaceuticals. American Journal of Health Systems in Pharmacy, 58(21), 2033–41.Google Scholar
Lambert, BL, Lin, SJ, Tan, H. (2005). Designing safe drug names. Drug Safety, 28(6), 495–512.CrossRefGoogle ScholarPubMed
McGee, DC, Gould, MK. (2003). Preventing complications of central venous catheterization. New England Journal of Medicine, 348(12), 1123–33.CrossRefGoogle ScholarPubMed
,National Patient Safety Agency. Patient Safety Alert 20: Promoting Safer Use of Injectable Medicines. March 2007.
Neff, TA, Fischer, JE, Schulz, G, Baenziger, O, Weissm, M. (2001). Infusion pump performance with vertical displacement: effect of syringe pump and assembly type. Intensive Care Medicine, 27(1), 287–91.CrossRefGoogle ScholarPubMed
Nolan, JP, Deakin, CD, Soar, J, Bottiger, BW, Smith, G. (2005). European Resuscitation Council guidelines for resuscitation 2005. Section 4. Adult advanced life support. Resuscitation, 67 Suppl. 1, S39–86.CrossRefGoogle ScholarPubMed
O'Hanlon, S. (2008). Delivering intravenous therapy in the community setting. Nursing Standard, 22(31), 44–8.Google ScholarPubMed
Pratt, RJ, Pellowe, CM, Wilson, JA. (2007). epic2: National evidence-based guidelines for preventing healthcare-associated infections in NHS hospitals in England. Journal of Hospital Infection, 65 Suppl. 1, S1–64.CrossRefGoogle ScholarPubMed
Small, SP. (2004). Preventing sciatic nerve injury from intramuscular injections: literature review. Journal Advanced of Nursing, 47(3), 287–96.CrossRefGoogle ScholarPubMed
Soar, J, Pumphrey, R, Cant, A, et al. (2008). Emergency treatment of anaphylactic reactions – guidelines for healthcare providers. Resuscitation, 77(2), 157–69.CrossRefGoogle ScholarPubMed
Tarantola, A, Abiteboul, D, Rachine, A. (2006). Infection risks following accidental exposure to blood or body fluids in health care workers: a review of pathogens transmitted in published case. American Journal on Infection Control, 34(6), 367–75.CrossRefGoogle ScholarPubMed
Taxis, K, Barber, N. (2003). Ethnographic study of incidence and severity of intravenous drug errors. British Medical Journal, 326(7391), 684.CrossRefGoogle ScholarPubMed
Turcotte, S, Dube, S, Beauchamp, G. (2006). Peripherally inserted central venous catheters are not superior to central venous catheters in the acute care of surgical patients on the ward. World Journal of Surgery, 30(8), 1605–19.CrossRefGoogle Scholar
,University College Hospitals Pharmacy Department. Injectable Medicines Administration Guide. 2nd edition (2007). Oxford, UK: Blackwell Publishing.Google Scholar
Viscusi, ER. (2008). Patient-controlled drug delivery for acute postoperative pain management: a review of current and emerging technologies. Regional Anesthesia and Pain Medicine, 33(2), 146–58.Google ScholarPubMed
Wright, K. (2008). Drug calculations part 1: a critique of the formula used by nurses. Nursing Standard, 22(36), 40–2.CrossRefGoogle ScholarPubMed
Wynaden, D, Landsborough, I, Chapmen, R, McGowan, S, Lapsley, J, Finn, M. (2005). Establishing best practice guidelines for administration of intramuscular injections in the adult: a systematic review of the literature. Contemporary Nurse, 20(2), 267–77.CrossRefGoogle ScholarPubMed
Young, TN, Arens, FJ, Kennedy, GE, Laurie, JW, Rutherford, G. (2007). Antiretroviral post-exposure prophylaxis (PEP) for occupational HIV exposure. Cochrane Database Systems Review(1), CD002835.CrossRefGoogle ScholarPubMed
Zaybak, A, Gunes, UY, Tamsel, S, Khorshid, L, Eser, I. (2007). Does obesity prevent the needle from reaching muscle in intramuscular injections?Journal of Advanced Nursing, 58(6), 552–6.CrossRefGoogle ScholarPubMed

Save book to Kindle

To save this book to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×