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41 - Care of the peripartum patient

Published online by Cambridge University Press:  12 January 2010

Clyde Watkins
Affiliation:
Emory University, School of Medicine, Atlanta, GA
Michael F. Lubin
Affiliation:
Emory University, Atlanta
Robert B. Smith
Affiliation:
Emory University, Atlanta
Thomas F. Dodson
Affiliation:
Emory University, Atlanta
Nathan O. Spell
Affiliation:
Emory University, Atlanta
H. Kenneth Walker
Affiliation:
Emory University, Atlanta
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Summary

Introduction

The past two decades have brought a greater understanding of pregnancy along with advances in the recognition and management of disorders that are unique to pregnancy or complicate pregnancy. Increasingly, generalist physicians are being asked to assist in the management of medical conditions that develop prior to or as a result of pregnancy. Coverage of the breadth of medical disorders that can complicate pregnancy is the topic of several excellent textbooks. Instead, this chapter focuses on the medical care of several conditions that are unique to pregnancy or influenced by the physiologic changes that occur around late pregnancy, labor, delivery and the immediate postpartum period.

Normal physiologic changes in pregnancy

Knowledge of the normal physiologic changes that occur with pregnancy is important to understand the effect that existing maternal disease has on maternal and fetal health. A few of the more important physiologic changes associated with pregnancy are listed in Table 41.1.

The hemodynamic adaptations are some of the most significant physiologic changes that occur during pregnancy. Soon after implantation systemic vascular resistance (SVT) falls. This adaptation, mediated by gestational hormones, prostaglandins and the creation of a low resistance circulation in the uterus and placenta, reaches its nadir at 20 weeks gestation. During the latter half of pregnancy, the SVR rises, reaching near normal levels at term. Cardiac output rises 30%–50% during pregnancy. An increased stroke volume, a result of expanded blood volume, accounts for the majority of the increase in CO in the early stages of pregnancy.

Type
Chapter
Information
Medical Management of the Surgical Patient
A Textbook of Perioperative Medicine
, pp. 503 - 512
Publisher: Cambridge University Press
Print publication year: 2006

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References

Balk, M. A. & Watkins, C. Heart disease in pregnancy. In Branch, W. T., Alexander, R. W., Schlant, R. C., & Hurst, J. W., eds. Cardiology in Primary Care. New York: McGraw-Hill, 2000: 791–805.Google Scholar
Poppas, A., Carson, M. P., Rosene-Montella, K., & Powrie, R. O. Cardiovascular disease. In Lee, R. V., Rosene-Montelle, K., Barbour, L. A.et al. eds. Medical Care of the Pregnant Patient. Philadelphia: American College of Physicians, 2000: 345–386.Google Scholar
National High Blood Pressure Education Program Working Group Report on High Blood Pressure in Pregnancy. Report of the National High Blood Pressure Education Program Working Group on high blood pressure in pregnancy. NIH Publication # 00–3029, 2000: 1–38.
Roberts, J. M. & Redman, C. W.Preeclampsia: more than pregnancy-induced hypertension. Lancet 1993; 341: 1447–1451.CrossRefGoogle ScholarPubMed
Powrie, R. O. & Rosene-Montella, K. Hypertension and preeclampsia. In Lee, R. V., et al., eds. Medical Care of the Pregnant Patient. Philadelphia, PA: American College of Physicians, 2000; 185–205.Google Scholar
Mabie, W. C.Management of acute severe hypertension and encephalopathy. Clin. Obstet. Gynecol. 1999; 42(3): 519–531.CrossRefGoogle ScholarPubMed
Watkins, C., Bernstein, L. B., & Higgins, S. M. Medical disorders of pregnancy. In Branch, W. T., ed. Office Practice of Medicine. 609–620 Philadelphia, PA: W. B. Saunders, 2000: 609–620.Google Scholar
Sibai, B. M. & Lindeheimer, M.Risk factors for preeclampsia, abruptio placentae and adverse neonatal outcomes among women with chronic hypertension. N. Engl. J. Med. 1998; 339(10): 667–671.CrossRefGoogle ScholarPubMed
Ferrer, R. L. & Sibai, B. M.Management of mild chronic hypertension during pregnancy: a review. Obstet. Gynecol. 2000; 96(5): 849–860.Google ScholarPubMed
Garovic, V.Hypertension in pregnancy: diagnosis and treatment. Mayo Clin. Proc. 2000; 75: 1071–1076.CrossRefGoogle ScholarPubMed
Brown, C. S. & Bertolet, B. D.Peripartum cardiomyopathy: a comprehensive review. Am. J. Obstet. Gynecol. 1998; 178(2): 409–414.CrossRefGoogle ScholarPubMed
Beus, E., Mook, W. N. K. A., Ramsey, G.et al. Peripartum cardiomyopathy: a condition intensivists should be aware of. Intens. Care Med. 2003; 29: 167–174.CrossRefGoogle Scholar
Lampert, M. D. & Weinert, L.Contractile reserve in patients with peripartum cardiomyopathy and recovered left ventricular function. Am. J. Obstet. Gynecol. 1997; 176(1): 187–195.CrossRefGoogle ScholarPubMed
Toglia, M. R. & Weg, J. G.Venous thromboembolism during pregnancy. N. Engl. J. Med. 1996; 335(2): 108–114.CrossRefGoogle ScholarPubMed
Rosene-Montella, K. & Barbour, L. A. Thromboembolic disease and hypercoagulable states. In Lee, R. V.et al., eds. Medical Care of the Pregnant Patient. Philadelphia: American College of Physicians, 2000: 423–448.Google Scholar
Spritzer, C. E., Evans, A. C., & Kay, H. H.Magnetic resonance imaging of deep venous thrombosis in pregnant women with lower extremity edema. Obstet. Gynecol. 1995; 85: 603–607.CrossRefGoogle ScholarPubMed
Ginsberg, J. A. S., Hirsh, J., Turner, D. C., et al. Risks to the fetus of anticoagulant therapy during pregnancy. Thromb. Haemost. 1989; 61: 197–203.Google ScholarPubMed
Laurent, P., Dussarat, G. V., Bonal, J.et al. Low molecular weight heparins: a guide to their optimum use in pregnancy. Drugs 2002; 62(3): 463–477.CrossRefGoogle ScholarPubMed
Davidson, K. M.Intrahepatic cholestasis of pregnancy. Semin Perinatol. 1998; 22(2): 104–111.CrossRefGoogle ScholarPubMed
Reyes, H.Intrahepatic cholestasis of pregnancy: estrogen related disease. Semin. Liver Dis. 1993; 13: 289–301.CrossRefGoogle ScholarPubMed
Knox, T. A. & Olans, L. B.Liver disease in pregnancy. N. Engl. J. Med. 1996; 335(8): 569–576.CrossRefGoogle ScholarPubMed
Reyes, H.The spectrum of liver and gastrointestinal disease seen in cholestasis of pregnancy. Gastroenterol. Clin. North Am. 1992; 21: 905–921.Google ScholarPubMed
Heikkinen, J.Serum bile acids in the early diagnosis of intrahepatic cholestasis of pregnancy. Obstet. Gynecol. 1983; 61: 581–587.Google ScholarPubMed
Pockros, P. J., Peters, R. L., & Reynolds, T. B.Idiopathic fatty liver of pregnancy: findings in ten cases. Medicine 1984; 63: 1–11.CrossRefGoogle ScholarPubMed
Ibdah, S. A., Bennett, M. J., Rinaldo, P., Zhao, Y.et al. A fetal fatty acid oxidation disorder as a cause of liver disease in pregnant women. N. Engl. J. Med. 1999; 340(22): 1723–1731.CrossRefGoogle ScholarPubMed
Bacq, Y.Acute fatty liver of pregnancy. Semin. Perinat. 1998; 22(2): 134–140.CrossRefGoogle ScholarPubMed
Riely, C. A. Gestational liver disease. In Lee, R. V., et al., eds. Medical Care of the Pregnant Patient. Philadelphia: American College of Physicians, 2000: 585–598.Google Scholar
Saphier, C. J. & Repke, J. T.Hemolysis, elevated liver enzymes and low platelets (HELLP) syndrome: a review of diagnosis and management. Semin. Perinatol. 1998; 22(2): 118–133.CrossRefGoogle ScholarPubMed
Sabai, B. M., Ramadan, M. K., Usta, I.et al. Maternal morbidity and mortality in 442 pregnancies with hemolysis, elevated liver enzymes, and low platelets (HELLP syndrome). Am. J. Obstet. Gynecol. 1993; 169: 1000–1006.CrossRefGoogle Scholar
Hermis, K., Rath, W., Herting, E., & Kuhn, W.Maternal hemolysis, elevated liver enzymes and low platelet count, and neonatal outcome. Am. J. Perinatol. 1995; 12: 1–6.CrossRefGoogle Scholar
Egerman, R. S. & Sibai, B. M.Imitators of preeclampsia and eclampsia. Clin. Obstet. Gynecol. 1999; 42(3): 551–562.CrossRefGoogle ScholarPubMed
Magann, E. F. & Martin, J. N.Twelve steps to optimal management of HELLP syndrome. Clin. Obstet. Gynecol. 1999; 42(3): 532–550.CrossRefGoogle ScholarPubMed
Varol, F., Aydin, T., & Gucer, F.HELLP syndrome and postpartum corticosteroids. Int. J. Gynecol. Obstet. 2001; 73: 157–159.CrossRefGoogle ScholarPubMed

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