Book contents
- Liver Disease in Children
- Liver Disease in Children
- Copyright page
- Contents
- Contributors
- Preface
- Section I Pathophysiology of Pediatric Liver Disease
- Section II Cholestatic Liver Disease
- Chapter 8 Approach to the Infant with Cholestasis
- Chapter 9 Medical and Nutritional Management of Cholestasis in Infants and Children
- Chapter 10 Neonatal Hepatitis and Congenital Infections
- Chapter 11 Biliary Atresia and Other Disorders of the Extrahepatic Bile Ducts
- Chapter 12 Neonatal Jaundice and Disorders of Bilirubin Metabolism
- Chapter 13 Familial Hepatocellular Cholestasis
- Chapter 14 Alagille Syndrome
- Chapter 15 Intestinal Failure Associated Liver Disease
- Chapter 16 Diseases of the Gallbladder in Infancy, Childhood, and Adolescence
- Section III Hepatitis and Immune Disorders
- Section IV Metabolic Liver Disease
- Section V Other Considerations and Issues in Pediatric Hepatology
- Index
- References
Chapter 12 - Neonatal Jaundice and Disorders of Bilirubin Metabolism
from Section II - Cholestatic Liver Disease
Published online by Cambridge University Press: 19 January 2021
Book contents
- Liver Disease in Children
- Liver Disease in Children
- Copyright page
- Contents
- Contributors
- Preface
- Section I Pathophysiology of Pediatric Liver Disease
- Section II Cholestatic Liver Disease
- Chapter 8 Approach to the Infant with Cholestasis
- Chapter 9 Medical and Nutritional Management of Cholestasis in Infants and Children
- Chapter 10 Neonatal Hepatitis and Congenital Infections
- Chapter 11 Biliary Atresia and Other Disorders of the Extrahepatic Bile Ducts
- Chapter 12 Neonatal Jaundice and Disorders of Bilirubin Metabolism
- Chapter 13 Familial Hepatocellular Cholestasis
- Chapter 14 Alagille Syndrome
- Chapter 15 Intestinal Failure Associated Liver Disease
- Chapter 16 Diseases of the Gallbladder in Infancy, Childhood, and Adolescence
- Section III Hepatitis and Immune Disorders
- Section IV Metabolic Liver Disease
- Section V Other Considerations and Issues in Pediatric Hepatology
- Index
- References
Summary
Elevation of the serum bilirubin level is a common finding during the first week of life. This can be a transient phenomenon that resolves spontaneously, or it can signify a serious or even potentially life-threatening condition. There are many causes of hyperbilirubinemia, and each has its own prognostic and therapeutic implications. Independent of the etiology, elevated serum bilirubin levels can be potentially toxic to the newborn infant. This chapter will review perinatal bilirubin metabolism and address assessment, etiology, toxicity, and therapy for neonatal jaundice. Finally, the diseases in which there is a primary disorder in the metabolism of bilirubin will be reviewed regarding their clinical presentation, pathophysiology, diagnosis, and treatment. For more extensive referencing, see this chapter in the third edition of this textbook [1].
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- Information
- Liver Disease in Children , pp. 182 - 203Publisher: Cambridge University PressPrint publication year: 2021
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