Principles Underlying Kinetic and Pharmacodynamic Drug Interactions; Clinically Relevant Drug Interactions and Their Management
Published online by Cambridge University Press: 09 February 2024
As clinical psychopharmacology moves into the twenty-first century, there is an emphasis on rational prescribing practices informed by pharmacokinetic principles and clinical dictates. Publications note that certain oral medications which historically were dosed more than once per day (e.g. most antipsychotics including clozapine) have comparable efficacy with nightly (QHS) dosing for the majority of patients [1–3].
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