This chapter shows how to use causal models to inform the selection of cases for intensive analysis. We outline a procedure in which we predict the inferences that will be made when future data are found and use these predictions to inform case-selection strategies. We ask: Given a set of cases on which we already have data on X and Y, which cases will it be most advantageous to choose for more in-depth investigation? We show that the optimal case-selection strategy depends jointly on the model we start with and the causal question we seek to answer and draw out the implication that researchers should be wary of generic case-selection principles.