This chapter discusses the coevolution of the health care and the public health sectors in the United States (U.S.). I selected it as case study because it combines a fragmented government with high professionalism as well as a competitive system of interest aggrega- tion. Therefore, health care and public health should coevolve in a loosely coupled manner; in case the contextual conditions are favorable for responsiveness. In other words, if policy demands require an integration of health care and public health, or more public health policies, there should be responsiveness between health care and public health in the U.S. The results of the case study confirm my initial hypothesis partially. During t0, the two sectors were loosely coupled and coevolved towards de-coupling and then back towards loose coupling during the later time periods.