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Chapter I

from Drugs: An A–Z Guide

Henry G. W. Paw  and
Rob Shulman
Henry G. W. Paw
Affiliation:
York Hospital, York
Rob Shulman
Affiliation:
University College London Hospitals, London
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Summary

Human normal immunoglobulin is prepared by cold alcohol fractionation of pooled plasma from over 1,000 donations. Individual donor units of plasma are screened for hepatitis B surface antigen (HBsAg) and for the presence of antibodies to human immunodeficiency virus type 1 (HIV-1), HIV-2 or hepatitis C virus (HCV), which, combined with careful donor selection, minimizes the risk of viral transmission. In addition, the testing for HBsAg, HIV-1, HIV-2 and HCV antibodies is repeated on the plasma pools.

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Handbook of Drugs in Intensive Care
An A-Z Guide
 , pp. 162 - 170
Publisher: Cambridge University Press
Print publication year: 2025

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  • Chapter I
  • Henry G. W. Paw, York Hospital, York, Rob Shulman, University College London Hospitals, London
  • Book: Handbook of Drugs in Intensive Care
  • Online publication: 15 January 2025
  • Chapter DOI: https://doi.org/10.1017/9781009429702.012
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  • Chapter I
  • Henry G. W. Paw, York Hospital, York, Rob Shulman, University College London Hospitals, London
  • Book: Handbook of Drugs in Intensive Care
  • Online publication: 15 January 2025
  • Chapter DOI: https://doi.org/10.1017/9781009429702.012
Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • Chapter I
  • Henry G. W. Paw, York Hospital, York, Rob Shulman, University College London Hospitals, London
  • Book: Handbook of Drugs in Intensive Care
  • Online publication: 15 January 2025
  • Chapter DOI: https://doi.org/10.1017/9781009429702.012
Available formats
×