This chapter explores two case histories where American politicians appear to have sided with intense minorities over less-intense majorities. First, I present the case of federal funding for stem cell research in the early 2000s. I find evidence that majorities supported allocating federal health research funds toward research using embryonic stem cells yet federal policy remained stringent for most of the decade. Second, I present the case of firearm regulation following the mass shooting at Sandy Hook Elementary School in 2012. Although large majorities indicated support for new regulation of firearms, no new regulations passed Congress. An intense minority appears to have used costly political action to communicate their strong opposition to new regulations.