from Section II - Executive Dysfunction in the Neurodevelopmental and Acquired Disorders
Published online by Cambridge University Press: 05 October 2012
Several childhood movement disorders have frequently been linked to EdF due to involvement of the fronto-subcortical circuits affecting both motor and cognitive functions. The current chapter includes discussion of involuntary movement disorders (i.e., Tourette syndrome, PANDAS, and Sydenham's Chorea) and motor control disorders (i.e., cerebral palsy).
Tourette syndrome
Tourette Syndrome (TS; a.k.a. Tourette's Disorder) is a child-onset neurodevelopmental condition characterized by the presence of chronic motor and vocal tics that may wax and wane over time. Tics are defined as “sudden, rapid, recurrent, nonrhythmic motor movements or vocalizations”. TS has a prevalence of approximately 1% and occurs more frequently in boys as compared to girls, at a ratio of approximately 4:1. Onset of symptoms generally occurs in early childhood with possible worsening of symptoms during adolescence. Tics may decline or remit in adulthood, though approximately 20% of individuals experience persisting tics into adulthood. TS commonly co-occurs with a variety of conditions, particularly ADHD and OCD, with comorbidity estimates of 35% and 41%, respectively.
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