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9 - Pharyngitis and Tonsillitis

from Part I - Systems

Published online by Cambridge University Press:  15 December 2009

Theresa A. Gurney
Affiliation:
Department of Otolaryngology–Head and Neck Surgery, University of California, San Francisco School of Medicine, San Francisco General Hospital, San Francisco, CA
Andrew H. Murr
Affiliation:
Professor of Clinical Otolaryngology–Head and Neck Surgery, University of California, San Francisco School of Medicine, Chief of Service San Francisco General Hospital, San Francisco, CA
Rachel L. Chin
Affiliation:
University of California, San Francisco
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Summary

INTRODUCTION – AGENTS

Pharyngitis and tonsillitis both are most frequently caused by Streptococcus pyogenes (group A beta-hemolytic streptococcus). However, many other organisms have been cultured in pharyngitis and tonsillitis, including viridans group Streptococci, Staphylococcus aureus, and Haemophilus influenzae. Oral flora such as Actinomyces can also be a bacterial etiology. It is not uncommon for the infection to be caused by a mix of aerobic and anaerobic flora.

Viruses with a predilection for the upper respiratory tract can also be causative and are, in fact, more prevalent. These include rhinoviruses, influenza viruses, adenovirus, enteroviruses, reovirus, respiratory syncytial virus, parainfluenza viruses, and coronaviruses. Infection with the Epstein-Barr virus (EBV) is common and may be accompanied by extensive tonsillar exudates. Other etiologies include toxoplasmosis, candida, tularemia, and cytomegalovirus.

EPIDEMIOLOGY

Pharyngitis and tonsillitis are most commonly seen in children and teenagers (though rarely in children under 2), and are not unusual in adults. In general, it is more likely for children than for adults to have a bacterial etiology of a sore throat. There is a peak incidence in Streptococcus pharyngitis from November to May.

CLINICAL FEATURES

Pharyngitis and tonsillitis both present with dysphagia, odynophagia, and a low-grade fever (Table 9.1). There may be erythema of the pharynx. In a tonsillar infection in which the many crevices (or crypts) harbor bacterial infection, patients may complain of bad breath and foul-tasting whitish lumps on the tonsils.

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Publisher: Cambridge University Press
Print publication year: 2008

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References

Bisno, A L, Gerber, M A, Gwaltney, J M Jr, et al. Practice guidelines for the diagnosis and management of group A streptococcal pharyngitis: Infectious Diseases Society of America. Clin Infect Dis 2002:35:113–25.CrossRefGoogle Scholar
Cooper, R J, Hoffman, J R, Bartlett, J G. Principles of appropriate antibiotic use for acute pharyngitis in adults: background. Ann Intern Med 2001;134:509.CrossRefGoogle ScholarPubMed
Fairbanks, D N F. Pocket guide to antimicrobial therapy in otolaryngology – head and neck surgery, 12th ed. Washington, DC: American Academy of Otolaryngology, 2005.Google Scholar
Orvidas, L J, Slattery, M J. Pediatric autoimmune neuropsychiatric disorders and streptococcal infections: role of otolaryngologist. Laryngoscope 2001;111(9):1515–9.CrossRefGoogle ScholarPubMed

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  • Pharyngitis and Tonsillitis
    • By Theresa A. Gurney, Department of Otolaryngology–Head and Neck Surgery, University of California, San Francisco School of Medicine, San Francisco General Hospital, San Francisco, CA, Andrew H. Murr, Professor of Clinical Otolaryngology–Head and Neck Surgery, University of California, San Francisco School of Medicine, Chief of Service San Francisco General Hospital, San Francisco, CA
  • Edited by Rachel L. Chin, University of California, San Francisco
  • Book: Emergency Management of Infectious Diseases
  • Online publication: 15 December 2009
  • Chapter DOI: https://doi.org/10.1017/CBO9780511547454.010
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  • Pharyngitis and Tonsillitis
    • By Theresa A. Gurney, Department of Otolaryngology–Head and Neck Surgery, University of California, San Francisco School of Medicine, San Francisco General Hospital, San Francisco, CA, Andrew H. Murr, Professor of Clinical Otolaryngology–Head and Neck Surgery, University of California, San Francisco School of Medicine, Chief of Service San Francisco General Hospital, San Francisco, CA
  • Edited by Rachel L. Chin, University of California, San Francisco
  • Book: Emergency Management of Infectious Diseases
  • Online publication: 15 December 2009
  • Chapter DOI: https://doi.org/10.1017/CBO9780511547454.010
Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • Pharyngitis and Tonsillitis
    • By Theresa A. Gurney, Department of Otolaryngology–Head and Neck Surgery, University of California, San Francisco School of Medicine, San Francisco General Hospital, San Francisco, CA, Andrew H. Murr, Professor of Clinical Otolaryngology–Head and Neck Surgery, University of California, San Francisco School of Medicine, Chief of Service San Francisco General Hospital, San Francisco, CA
  • Edited by Rachel L. Chin, University of California, San Francisco
  • Book: Emergency Management of Infectious Diseases
  • Online publication: 15 December 2009
  • Chapter DOI: https://doi.org/10.1017/CBO9780511547454.010
Available formats
×