Published online by Cambridge University Press: 27 June 2019
Electroconvulsive therapy (ECT) possesses several key therapeutic actions, having antidepressant, anti-manic and antipsychotic effects. The adverse effects of ECT, particularly loss of autobiographical memories, are also of great clinical importance. Whether the same ‘mechanism’ underpins all these properties is unknown. Most information about the mechanistic effects of ECT has been obtained in relation to the treatment of depression and the current review will focus on this area.
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