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Chapter 41 - Treatment of Epithelial Ovarian Cancers, Fallopian Tube Cancers and Peritoneal Surface Cancers

from Section 9 - Ovary and Fallopian Tubes

Published online by Cambridge University Press:  24 November 2021

By
Céline Montavon Sartorius  and
Viola Heinzelmann-Schwarz
Edited by
Tahir Mahmood ,
Charles Savona-Ventura ,
Ioannis Messinis  and
Sambit Mukhopadhyay
Tahir Mahmood
Affiliation:
Victoria Hospital, Kirkcaldy
Charles Savona-Ventura
Affiliation:
University of Malta, Malta
Ioannis Messinis
Affiliation:
University of Thessaly, Greece
Sambit Mukhopadhyay
Affiliation:
Norfolk & Norwich University Hospital, UK
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Summary

Epithelial ovarian cancer is currently still treated with chemotherapy using carboplatin and paclitaxel in a 3-weekly regimen. Maintenance treatment is started, using targeted therapy with anti-VEGF bevacizumab or PARP inhibitor olaparib. In the recurrent setting the classical platinum-resistant or -sensitive cut-off has loosened and these days time to next subsequent treatment is increasingly used. New drugs are being investigated in ovarian cancer, mainly CDK4/5 inhibitors and checkpoint inhibitors.

Keywords

cancerepithelialfallopianperitonealtreatmentsurgerychemotherapy
Type
Chapter
Information
The EBCOG Postgraduate Textbook of Obstetrics & Gynaecology
Gynaecology
 , pp. 357 - 365
Publisher: Cambridge University Press
Print publication year: 2021

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References

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