After considering On Breaths’ “Gorgianic” style and the disputed attribution of this text to Hippocrates, this chapter argues that the author’s attribution of all diseases to pneuma is not as revolutionary as it initially appears. By relying on widely attested views about what pneuma tends to do within the body, this author is in fact remarkably conservative when constructing his own theories of pathogenesis. This chapter then turns to the more important question of why this author felt compelled to identify a single cause of all diseases. On the one hand, we can point to the same interest in remote and proximate causes that we see in On the Nature of the Human Being. At the same time, this author seems to be driven by a separate “cosmological impulse,” the belief that high-level commonalities, whatever their applicability, are inherently desirable and directly relevant to the medical art.