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Chapter 36 - Haematology

from Section 8 - Miscellaneous Topics

Published online by Cambridge University Press:  12 May 2020

By
Martin W. Besser  and
Kiran M. P. Salaunkey
Edited by
Joseph Arrowsmith ,
Andrew Roscoe  and
Jonathan Mackay
Joseph Arrowsmith
Affiliation:
Royal Papworth Hospital, Cambridge
Andrew Roscoe
Affiliation:
Singapore General Hospital
Jonathan Mackay
Affiliation:
Royal Papworth Hospital, Cambridge
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Summary

Over the last decade, there have been three major developments in perioperative blood management. Firstly, the recognition of preoperative anaemia and perioperative transfusion as risk factors for perioperative morbidity and mortality. Secondly, there is much greater involvement of haematologists in preoperative planning and perioperative care. Thirdly, there has been a widespread introduction of point-of-care testing and aggressive, protocol-driven blood component use in the management of perioperative bleeding.

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Chapter
Information
Core Topics in Cardiac Anaesthesia , pp. 261 - 268
Publisher: Cambridge University Press
Print publication year: 2020

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References

Further Reading

Besser, MW, Klein, AA. The coagulopathy of cardiopulmonary bypass. Crit Rev Clin Lab Sci 2010; 47: 197–212.CrossRefGoogle ScholarPubMed
Besser, MW, Ortmann, E, Klein, AA. Haemostatic management of cardiac surgical haemorrhage. Anaesthesia 2015; 70 Suppl 1: 87–95.Google Scholar
Choxi, AA, Patel, PA, Augoustides, JG, et al. Bivalirudin for cardiopulmonary bypass in the setting of heparin-induced thrombocytopenia and combined heart and kidney transplantation – diagnostic and therapeutic challenges. J Cardiothorac Vasc Anesth 2017; 31: 354–64.CrossRefGoogle ScholarPubMed
Edwin, F, Aniteye, E, Tettey, M, et al. Hypothermic cardiopulmonary bypass without exchange transfusion in sickle-cell patients: a matched-pair analysis. Interact Cardiovasc Thorac Surg 2014; 19: 771–6.CrossRefGoogle ScholarPubMed
Estcourt, LJ, Birchall, J, Allard, S, et al. Guidelines for the use of platelet transfusions. Br J Haematol 2017; 176: 365–94.CrossRefGoogle ScholarPubMed
Hung, M, Ortmann, E, Besser, M et al. A prospective observational cohort study to identify the causes of anaemia and association with outcome in cardiac surgical patients. Heart 2015; 101: 107–12.CrossRefGoogle ScholarPubMed
Nickel, KF, Long, AT, Fuchs, TA, Butler, LM, Renne, T. Factor XII as a therapeutic target in thromboembolic and inflammatory diseases. Arterioscler Thromb Vasc Biol 2017; 37: 13–20.CrossRefGoogle ScholarPubMed
Ortmann, E, Besser, MW, Klein, AA. Antifibrinolytic agents in current anaesthetic practice. Br J Anaesth 2013; 111: 549–63.CrossRefGoogle ScholarPubMed
Rodeghiero, F, Tosetto, A, Abshire, T, et al. ISTH/SSC bleeding assessment tool: a standardized questionnaire and a proposal for a new bleeding score for inherited bleeding disorders. J Thromb Haemost 2010; 8: 2063–5.CrossRefGoogle Scholar
Royston, D. Aprotinin; an economy of truth? J Thorac Cardiovasc Surg 2008; 136: 798-9.CrossRefGoogle ScholarPubMed
Staibano, P, Arnold, DM, Bowdish, DM, Nazy, I. The unique immunological features of heparin-induced thrombocytopenia. Br J Haematol 2017; 177: 198–207.CrossRefGoogle ScholarPubMed
Thachil, J, Warkentin, TE. How do we approach thrombocytopenia in critically ill patients? Br J Haematol 2017; 177: 27–38.CrossRefGoogle ScholarPubMed

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