Since manipulation is a relation involving power over another, it is alleged that it necessarily manifests disrespect toward persons. The analysis in the chapter explores this claim and rejects it. The following broad arguments are advanced: (1) The essence of manipulation is treating others as if they are machines (mechanification); it is therefore natural to examine whether manipulation manifests the same disrespect involved in objectification. The analysis rejects this possibility. (2) The dichotomy between “respectful influence through rational persuasion” and “disrespectful influence via (soft) power” is deconstructed. It is important to treat others “as rational,” but this can involve various elements of soft power, and thus manipulation need not be disrespectful. (3) Even “treating as rational” is not necessary for respect – there are other modes of interaction and influence which manipulations can exhibit that are not disrespectful. Play is analyzed in this regard. (4) Manipulation is often essential for promoting respect for persons through politeness and shielding privacy. The chapter ends by considering the virtuous person as regards the use of manipulation.