The final chapter focuses on many of the common obstacles that may surface and impede ComB therapy. A range of possible solutions are provided to address issues such as when a BFRB is comorbid with attention deficit hyperactivity disorder, depression, obsessive compulsive disorder, and anxiety, as well as with features such as perfectionism, low motivation, ambivalence, readiness for treatment, and lack of adherence to therapy recommendations. Also covered in this chapter are common mistakes made by therapists, issues of relapse prevention and possible future directions for maximizing the effectiveness and efficiency of ComB treatment.