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Chapter 5 - Personalized Network Modeling in Epilepsy

Published online by Cambridge University Press:  06 January 2023

By
Yujiang Wang ,
Gabrielle Marie Schroeder ,
Nishant Sinha  and
Peter Neal Taylor
Edited by
Rod C. Scott  and
J. Matthew Mahoney
Rod C. Scott
Affiliation:
University of Vermont
J. Matthew Mahoney
Affiliation:
University of Vermont
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Summary

Epilepsy is a family of neurological disorders in which patients experience unprovoked spontaneous seizures. Unfortunately, there is currently no cure for epilepsy, and seizure management is the target of most therapies. The first-line treatment of epilepsy is usually antiepileptic drugs. However, depending on the subtype of epilepsy and the individual, drug treatments fail to control the seizures in around one-third of patients. One challenge in the treatment of epilepsy is its heterogeneity. In each patient, seizures are thought to be generated by different mechanisms, processes, and parameters, and treatment outcomes will also depend on these.

Type
Chapter
Information
A Complex Systems Approach to Epilepsy
Concept, Practice, and Therapy
 , pp. 61 - 71
Publisher: Cambridge University Press
Print publication year: 2023

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