Prince, M, Knapp, M, Guerchet, M, et al. Dementia UK: Update Second Edition. King’s College London and London School of Economics for Alzheimer’s Society, 2014. Last accessed 13th October 2019 via: www.alzheimers.org.uk/sites/default/files/migrate/downloads/dementia_uk_update.pdfGoogle Scholar

Hill, L, Roberts, G, Wildgoose, J, Perkins, R, Hahn, S. Recovery and person-centred care in dementia: common purpose, common practice? Adv Psychiatr Treat 2010; 16: 288–98.\CrossRefGoogle Scholar

Royal College of Psychiatrists (RCPsych). Person-Centred Care: Implications for Training in Psychiatry [CR215]. RCPsych Person-Centred Training and Curriculum (PCTC) Scoping Group and the Special Committee on Professional Practice and Ethics, 2018. Last accessed on 9 September 2019 via: www.rcpsych.ac.uk/docs/default-source/improving-care/better-mh-policy/college-reports/college-report-cr215.pdf?sfvrsn=7863b905_2.Google Scholar

Dept of Health. Prime Minister’s Challenge on Dementia 2020. London: Department of Health, 2015. Last accessed on 13 September 2019 via: www.gov.uk/government/publications/prime-ministers-challenge-on-dementia-2020Google Scholar

Kitwood, T. Dementia Reconsidered: The Person Comes First. Open University Press, 1997.Google Scholar

Kitwood, T. Positive long-term changes in dementia: some preliminary observations. J of Mental Health 1995; 4: 133–44.CrossRefGoogle Scholar

Department of Health. No Health Without Mental Health: A Cross- government Mental Health Outcomes Strategy for People of All Ages. HM Government, 2011.Google Scholar

Antony, W. (1993) Recovery from mental illness: the guiding vision of the mental health service system in the 1990s. Psychosoc Rehabil J 1993; 16: 11–23.Google Scholar

Daley, S, Newton, D, Slade, M, Murray, J, Banerjee, S. Development of a framework for recovery in older people with mental disorder. Int J Geriatric Psychiatry 2013; 28: 522–9.Google Scholar

Repper, J, Perkins, R. Social Inclusion and Recovery. Ballière Tindall, 2003.Google Scholar

Shepherd, G, Boardman, J, Slade, M. Making Recovery a Reality. Sainsbury Centre for Mental Health, 2008.Google Scholar

Social Care Institute for Excellence (SCIE). Assessing the Mental Health Needs of Older People (Adults’ Services: SCIE Guide 03). SCIE, 2006.Google Scholar

Elwyn, G. Salzburg statement on shared decision making. Salzburg Global Seminar. BMJ 2011; 342: d1745.Google Scholar

Department of Health. Independence, Choice and Risk: A Guide to Best Practice in Supported Decision Making. Department of Health, 2007.Google Scholar

Alakeson, V, Perkins, R. Recovery, Personalisation and Personal Budgets. Centre for Mental Health, 2012.Google Scholar

Baker, E, Fee, J, Bovingdon, L, et al. From taking to using medication: recovery-focused prescribing and medicines management. Adv Psychiatr Treat 2013; 19: 2–10.Google Scholar

Department of Health. Self Care – A Real Choice. Self Care Support – A Practical Option. Department of Health, 2005.Google Scholar

Department of Health. Our Health, Our Care, Our Say. A New Direction for Community Services (White Paper). The Stationery Office, 2006.Google Scholar

Department of Health. Supporting People with Long-term Conditions to Self Care: A Guide to Developing Local Strategies and Good Practice. The Stationery Office, 2006.Google Scholar

Expert Patients Programme, Community Interest Company. Self Care Reduces Costs and Improves Health – The Evidence. Expert Patients Programme, 2010.Google Scholar

Expert Patients Programme, Community Interest Company. Healthy Lives Equalling Healthy Communities – The Social Impact of Selfmanagement. Expert Patients Programme, 2011.Google Scholar

Barlow, J, Wright, C, Sheasby, J, Turner, A, Hainsworth, J. Self-management approaches for people with chronic conditions: a review. Patient Educ Couns 2002; 48: 177–87.Google Scholar

Jonker, AAGC, Comijs, HC, Knipscheer, KC, Deeg, DJ. Promotion of self-management in vulnerable older people: a narrative literature review of outcomes of the chronic disease self-management program (CDSMP). Eur J Ageing 2009; 6: 303–14.Google Scholar

Mountain, GA. Self-management for people with early dementia: an exploration of concepts and supporting evidence. Dementia 2006; 5: 429–46.Google Scholar

Mountain, GA, Craig, CL. What should be in a self-management programme for people with early dementia? Aging Ment Health 2012; 16: 576–583.CrossRefGoogle Scholar

Reid, MC, Papaleontiou, M, Ong, A, et al. Self-management strategies to reduce pain and improve function among older adults in community settings: a review of the evidence. Pain Med 2008; 9: 409–24.Google Scholar

Laakkonen, ML, Kautiainen, H, Holtta, E, et al. Effects of self-management groups for people with dementia and their spouses – randomized controlled trial. J Am Geriatr Soc 2016; 64:752–760.CrossRefGoogle ScholarPubMed

Craig, C. Journeying through dementia: an occupational approach to supported self-management 2017. www.journeyingthroughdementia.com (accessed 18th March 2019).Google Scholar

Department of Health. Living Well with Dementia: A National Dementia Strategy. Department of Health, 2009.Google Scholar

Slade, M. 100 Ways to Support Recovery: A Guide for Mental Health Professionals. Rethink Recovery Series: Volume 1. Rethink, 2009.Google Scholar

Substance Abuse and Mental Health Services Administration (2010) Wellness Recovery Action Plan. SAMHSA’s National Registry of Evidence-based Programs and Practices (http://nrepp.samhsa.gov/ViewIntervention.aspx?id=208). Accessed 13 March 2013.Google Scholar

Perkins, R, Rinaldi, M. Taking Back Control: Planning Your Own Recovery. South West London and St George’s Mental Health NHS Trust, 2007.Google Scholar

Copeland, ME, McKay, M. The Depression Workbook: A Guide for Living with Depression and Manic Depression. New Harbinger Publications, 1992.Google Scholar

Leamy, M, Bird, V, Le Boutillier, C, Williams, J, Slade, M. Conceptual framework for personal recovery in mental health: systematic review and narrative synthesis. Br J Psychiatry 2011; 199: 445–52.Google Scholar

Mind. Life and Times of a Supermodel: The Recovery Paradigm for Mental Health. MindThink Report 3. Mind, 2008.Google Scholar

Health Foundation. Evidence: Helping People Help Themselves. Health Foundation, 2011.Google Scholar

McGorry, PD. The concept of recovery and secondary prevention in psychotic disorders. Aust N Z J Psychiatry 1992; 26: 3–17.Google Scholar

Office for National Statistics (ONS). National Population Projections: 2016-based Statistical Bulletin. ONS, 2016.Google Scholar

Hill, L, Roberts, G, Wildgoose, J, Perkins, R, Hahn, S. Recovery and person-centred care in dementia: common purpose, common practice? Adv Psychiatr Treat 2010; 16: 288–298.Google Scholar

Roberts, G, Boardman, J. Understanding ‘recovery’. Adv Psychiatr Treat 2013; 19: 400–409.Google Scholar

Davidson, L, Rakfeldt, J, Strauss, J. The Roots of the Recovery Movement in Psychiatry: Lessons Learned. Wiley-Blackwell, 2010.Google Scholar

Deegan, PE. Recovery as a journey of the heart. Psychiatr Rehabil J 1996; 19: 91–97.Google Scholar

Anthony, WA. Recovery from mental illness: the guiding vision of the mental health service system in the 1990s. Psychosoc Rehabil J 1993; 16: 11–23.Google Scholar

Woods, R. Recovery: is it relevant to older people? Signposts 2007; 12: 2–3.Google Scholar

Social Care Institute for Excellence (SCIE) Practice Guide 2: Assessing the Mental Health Needs of Older People. SCIE, 2006.Google Scholar

Rogers, CR. Client-Centred Therapy: Its Current Practices, Implications and Theory. Houghton Mifflin, 1951.Google Scholar

Kitwood, TM. Dementia Reconsidered: The Person Comes First. Open University Press, 1997.Google Scholar

PRAXIS. Training in psychiatry: making person-centred care a reality. BJPsych Bull 2019; 43: 136–140.Google Scholar

Gawande, A. Being Mortal: Illness, Medicine and What Matters in the End. Profile Books, 2014.Google Scholar

Gawande, A. Reith Lectures The Future of Medicine, 2014. Last accessed on 4 May 2020 via: www.bbc.co.uk/programmes/b04v380zGoogle Scholar

Daley, S, Newton, D, Slade, M, Murray, J, Banerjee, S. Development of a framework for recovery in older people with mental disorder, Int J Geriatr Psychiatry 2013; 28: 522–529.Google Scholar

Perkins, R, Hill, L, Daley, S, Chappell, M, Rennison, J. ‘Continuing to be Me’ – Recovering a Life with a Diagnosis of Dementia. ImROC, 2016. Last accessed on 23 September 2019 via: https://imroc.org/resources/12-continuing-recovering-life-diagnosis-dementia/Google Scholar

Office of the Deputy Prime Minister. Mental Health and Social Exclusion. Social exclusion unit report. ODPM Publications, 2004.Google Scholar

Local Government Association and Innovations in Dementia. Developing Dementia Friendly Communities. Learning and Guidance for Local Authorities, Local Government Association, 2012.Google Scholar

Shepherd, G, Boardman, J, Slade, M. Making Recovery a Reality. Sainsbury Centre for Mental Health, 2008.Google Scholar

National Institute for Health and Clinical Excellence & Social Care Institute for Clinical Excellence (NICE). Shared Decision Making, 2018. Last accessed on 23 September 2019 via: www.nice.org.uk/about/what-we-do/our-programmes/nice-guidance/nice-guidelines/shared-decision-makingGoogle Scholar

Dooley, J, Bass, N, Livingston, G, McCabe, R. Involving patients with dementia in decisions to initiate treatment: effect on patient acceptance, satisfaction and medication prescription. Br J Psychiatry 2019; 214: 213–217.CrossRefGoogle ScholarPubMed

Harman, G, Sims, K, Perkins, R. Living Well with Dementia. Life Changes, but Life Goes On… and that Life Can Be a Good Life. Central and North West London NHS Foundation Trust, 2019.Google Scholar

Mental Health Foundation. Still Going Strong. Mental Health Foundation, 2005.Google Scholar

Cheffey, J, Hill, L, McCullough, C, McCullough, C. Can I facilitate a project when my memory lets me down? The challenges and rewards of co-producing a ‘Living Well with Dementia’ course. Psychology of Older People: FPOP Bull 2017; 137: 19–25.Google Scholar

Copeland, ME. Wellness Recovery Action Plan. 1997. Last accessed on 23 September 2019 via: www.mentalhealthrecovery.comGoogle Scholar

The Health Foundation. Shine 2014 Final Report: A Study of the Use of Self-Management Techniques in Patients with Mild Cognitive Impairment, Devon Partnership NHS Trust, 2015.Google Scholar

Quinn, C, Toms, G, Jones, C, et al. A pilot randomized controlled trial of a self-management group intervention for people with early-stage dementia (The SMART study). Int Psychogeriatr 2016; 28: 787–800.Google Scholar

Care Services Improvement Partnership, Royal College of Psychiatrists & Social Care Institute for Excellence (CSIP, RCPsych & SCIE). A Common Purpose – Recovery in Future Mental Health Services (Joint Position Paper 08). SCIE, 2007.Google Scholar

Boardman, J, Roberts, G. Risk, Safety and Recovery. ImROC, 2014.Google Scholar

Bradford Dementia Group. DCM 8 User’s Manual: The DCM Method, 8th edition. Bradford, University of Bradford, 2005.Google Scholar

Litherland, R. Developing a National User Movement of People with Dementia. Learning from the Dementia Engagement and Empowerment Project (DEEP). Joseph Roundtree Foundation, 2015.Google Scholar

Patel, B, Perera, M, Pendleton, J, Richman, A, Majumdar, B. Psychosocial interventions for dementia: from evidence to practice. Adv Psychiatr Treat 2014; 20: 340–349.Google Scholar

Clarkson, P, Hughes, J, Xie, C, et al. Overview of systematic reviews: effective home support in dementia care, components and impacts-Stage 1, psychosocial interventions for dementia. J Adv Nurs 2017; 73: 2845–2863.Google Scholar

Guss, R, Middleton, J, Beanland, T, et al. A Guide to Psychosocial Interventions in Early Stages of Dementia. British Psychological Society, 2014.Google Scholar

Innes, A, Szymczynska, P, Stark, C. Dementia diagnosis and post-diagnostic support in Scottish rural communities: experiences of people with dementia and their families. Dementia 2012; 13: 233–247.Google Scholar

Chancellor, B, Duncan, A, Chatterjee, A. Art therapy for Alzheimer’s disease and other dementias. J Alzheimer’s Dis 2014; 39: 1–11.CrossRefGoogle ScholarPubMed

Deshmukh, S, Holmes, J, Cardno, A. Art therapy for people with dementia. Cochrane Database of Systematic Reviews. 2018. DOI:10.1002/14651858.CD011073.pub2Google Scholar

Hendriks, I, Meiland, F, Gerritsen, D, Dröes, R. Implementation and impact of unforgettable: an interactive art program for people with dementia and their caregivers. Int Psychogeriatr 2018; 31: 351–362.Google Scholar

Woods, B, O’Philbin, L, Farrell, E, Spector, A, Orrell, M. Reminiscence therapy for dementia. Cochrane Database of Systematic Reviews. 2018. DOI:10.1002/14651858.CD001120.pub3Google Scholar

Aleixo, M, Santos, R, Dourado, M. Efficacy of music therapy in the neuropsychiatric symptoms of dementia: systematic review. J Bras Psiquiatr 2017; 66: 52–61.Google Scholar

Noone, D, Stott, J, Aguirre, E, Llanfear, K, Spector, A. Meta-analysis of psychosocial interventions for people with dementia and anxiety or depression. Aging Ment Health 2018; 23: 1282–1291.Google Scholar

Ho, R, Sing, J, Lee, P, et al. A music intervention in managing agitation and aberrant motor behaviour among elders with dementia. Gerontologist 2016; 56(Suppl_3): 206–206.Google Scholar

Garridoa, S, Dunne, L, Chang, E, et al. The use of music playlists for people with dementia: a critical synthesis. J Alzheimers Dis 2017; 60: 1129–1142.Google Scholar

Iliff, J. The Glymphatic System in Alzheimer’s Disease. Presentation at: Knight Cardiovascular Institute, Oregon. Last accessed on 16 October 2019 via: www.alz.washington.edu/NONMEMBER/FALL15/DIR/Iliff.pdf Also see: Iliff JJ, Chen MJ, Plog BA, et al. Impairment of glymphatic pathway function promotes tau pathology after traumatic brain injury. J Neurosci 2014; 34: 16180–16193. DOI:10.1523/JNEUROSCI.3020-14.2014Google Scholar

Sekiguchi, H, Iritani, S, Fujita, K. Bright light therapy for sleep disturbance in dementia is most effective for mild to moderate Alzheimer’s type dementia: a case series. Psychogeriatrics 2017; 17: 275–281.Google Scholar

Mitolo, M, Tonon, C, La Morgia, C, et al. Effects of light treatment on sleep, cognition, mood, and behavior in Alzheimer’s disease: a systematic review. Dement Geriatr Cogn Disord 2018; 46: 371–384.Google Scholar

Jimbo, D, Inoue, M, Taniguchi, M, Urakami, K. Specific feature of olfactory dysfunction with Alzheimer’s disease inspected by the Odor Stick Identification Test. Psychogeriatrics 2011; 11: 196–204.Google Scholar

Yang, M-H, Lin, L-C, Wu, S-C, et al. Comparison of the efficacy of aroma-acupressure and aromatherapy for the treatment of dementia-associated agitation. BMC Complement Altern Med 2015; 15: 93. DOI:10.1186/s12906-015-0612-9Google Scholar

Jakob, A, Collier, L. Sensory enrichment for people living with dementia: increasing the benefits of multisensory environments in dementia care through design. Design Health 2017; 1: 115–33.Google Scholar

Wesenberg, S, Mueller, C, Nestmann, F, Holthoff‐Detto, V. Effects of an animal‐assisted intervention on social behaviour, emotions, and behavioural and psychological symptoms in nursing home residents with dementia. Psychogeriatrics 2018; 19: 219–27.Google Scholar

Zafra-Tanaka, JH, Pacheco-Barrios, K, Tellez, WA, Taype-Rondan, A. Effects of dog-assisted therapy in adults with dementia: a systematic review and meta-analysis. BMC Psychiatry 2019; 19: 41. DOI:10.1186/s12888-018-2009-zGoogle Scholar

Lamb, SE, Sheehan, B, Atherton, N, et al. Dementia and Physical Activity (DAPA) trial of moderate to high intensity exercise training for people with dementia: randomised controlled trial. Br Med J 2018; 361: k1675. DOI:https://doi.org/10.1136/bmj.k1675Google Scholar

Iuliano, E, di Cagno, A, Cristofano, A, et al. Physical exercise for prevention of dementia (EPD) study: background, design and methods. BMC Public Health 2019; 19: 659. DOI:10.1186/s12889-019-7027-3Google Scholar

Duan, Y, Lu, L, Chen, J, et al. Psychosocial interventions for Alzheimer’s disease cognitive symptoms: a Bayesian network meta-analysis. BMC Geriatr 2018; 18: 175. DOI:10.1186/s12877-018-0864-6Google Scholar

McDermott, O, Charlesworth, G, Hogervorst, E, et al. Psychosocial interventions for people with dementia: a synthesis of systematic reviews. Aging Ment Health 2018; 23: 393–403.Google Scholar

Travers, C, MacAndrew, M, Hines, S, et al. The effectiveness of meaningful occupation interventions for people living with dementia in residential aged care: a systematic review protocol. JBI Database System Rev Implement Rep 2015; 13: 87–99.Google Scholar

Moyle, W, Murfield, J, Jones, C, Beattie, E, Draper, B, Ownsworth, T. Can lifelike baby dolls reduce symptoms of anxiety, agitation, or aggression for people with dementia in long-term care? Findings from a pilot randomised controlled trial. Aging Ment Health 2019; 23: 1442–1450.CrossRefGoogle ScholarPubMed

Cantarella, A, Borella, E, Faggian, S, Navuzzi, A, De Beni, R. Using dolls for therapeutic purposes: a study on nursing home residents with severe dementia. Int J Geriatr Psychiatry 2018; 33: 915–25.Google Scholar

Mervin, MC, Moyle, W, Jones, C, et al. The cost-effectiveness of using Paro, a therapeutic robotic seal, to reduce agitation and medication use in dementia: findings from a cluster–randomized controlled trial. J Am Med Dir Assoc 2018; 19: 619–622.e1Google Scholar

Moyle, W, Jones, C, Murfield, J, et al. Using a therapeutic companion robot for dementia symptoms in long-term care: reflections from a cluster-RCT. Aging Ment Health 2017; 23: 329–36.Google Scholar

Czaja, SJ, Lee, CC, Perdomo, D, et al. Community REACH: an implementation of an evidence-based caregiver program. Gerontologist 2018; 58: e130–7.Google Scholar

Brooks, D, Fielding, E, Beattie, E, Edwards, H, Hines, S. Effectiveness of psychosocial interventions on the psychological health and emotional well-being of family carers of people with dementia following residential care placement. JBI Database System Rev Implement Rep 2018; 16: 1240–68.Google Scholar

Evans, S, Evans, S, Brooker, D, et al. The impact of the implementation of the Dutch combined Meeting Centres Support Programme for family caregivers of people with dementia in Italy, Poland and UK. Aging Ment Health 2018. https://doi.org/10.1080/13607863.2018.1544207Google Scholar

Oliveira, D, Orrell, M, Radburn, J. Health-promoting self-care in family carers of people with dementia. Alzheimers Dement 2018; 14: P1320.Google Scholar

Godwin, B. Hogewey: a ‘home from home’ in the Netherlands. J Dement Care 2015; 23: 28–31.Google Scholar

Woodbridge, R, Sullivan, M, Harding, E, et al. Use of the physical environment to support everyday activities for people with dementia: a systematic review. Dementia 2016; 17: 533–72.Google Scholar

Abraha, I, Rimland, J, Trotta, F, Dell’Aquila, G, Cruz-Jentoft, A, Petrovic, M, et al. Systematic review of systematic reviews of non-pharmacological interventions to treat behavioural disturbances in older patients with dementia. The SENATOR-OnTop series. BMJ Open. 2017; 7(3): e012759.Google Scholar

Livingston, G, Kelly, L, Lewis-Holmes, E, Baio, G, Morris, S, Patel, N, et al. Non-pharmacological interventions for agitation in dementia: systematic review of randomised controlled trials. British Journal of Psychiatry. 2014; 205(6): 436–442.Google Scholar

Scales, K, Zimmerman, S, Miller, S. Evidence-based nonpharmacological practices to address behavioral and psychological symptoms of dementia. The Gerontologist. 2018; 58(suppl_1): S88–S102.Google Scholar

Barraclough, J. ABC of palliative care. Depression, anxiety, and confusion. Br Med J 1997; 315: 1365–1368.Google Scholar

Spiess, JL, Northcott, CJ, Offsay, JD, Crossett, JH. Palliative care: something else we can do for our patients. Psychiatr Services 2002; 53: 1525–1526, 1529.Google Scholar

Black, D, Jolley, D. Slow euthanasia? The deaths of psychogeriatric patients. Br Med J 1990; 300: 1321–1323.Google Scholar

Black, D, Jolley, D. Deaths in psychiatric care. Int J Geriatr Psychiatry 1991; 6: 489–495.CrossRefGoogle Scholar

Addington-Hall, J. Positive Partnerships: Palliative Care for Adults with Severe Mental Health Problems. National Council for Hospice and Specialist Palliative Care Services, 2000.Google Scholar

Hughes, JC, Robinson, L, Volicer, L. Specialist palliative care in dementia. Br Med J 2005; 330: 57–58.Google Scholar

Volicer, L, Rheaume, Y, Brown, J, et al. Hospice approach to the treatment of patients with advanced dementia of the Alzheimer type. JAMA 1986; 256: 2210–2213.Google Scholar

Volicer, L. The development of palliative care for dementia. Ann Palliat Med 2017; 6: 302–305.Google Scholar

Hughes, JC, Jolley, D, Jordan, A, Sampson, EL. Palliative care in dementia: issues and evidence. Adv Psychiatr Treat 2007; 13: 251–260.Google Scholar

World Health Organization (2002). WHO Definition of Palliative Care. Available via: www.who.int/cancer/palliative/definition/en/ (last accessed 22 October 2019).Google Scholar

McInerney, F, Doherty, K, Bindoff, A, et al. How is palliative care understood in the context of dementia? Results from a massive open online course. Palliat Med 2018; 32: 594–602.Google Scholar

Addington-Hall, J. Reaching Out: Specialist Palliative Care for Adults with Non-Malignant Disease. Occasional Paper 14. National Council for Hospice and Specialist Palliative Care Services, 1998.Google Scholar

Sampson, EL, Gould, V, Lee, D, Blanchard, MR. Differences in care received by patients with and without dementia who died during acute hospital admission: a retrospective case note study. Age Ageing 2006; 35: 187–189.Google Scholar

Jolley, D, Baxter, D. Mortality in elderly patients with organic brain disorder enrolled on the Salford Psychiatric Case Register. Int J Geriatr Psychiatry 1997; 12: 1174–1181.Google Scholar

Mitchell, SL, Kiely, DK, Hamel, MB. Dying with advanced dementia in the nursing home. Arch Intern Med 2004; 164: 321–326.CrossRefGoogle ScholarPubMed

Aminoff, BZ, Adunsky, A. Their last 6 months: suffering and survival of end-stage dementia patients. Age Ageing 2006; 35: 597–601.Google Scholar

McCarthy, M, Addington-Hall, J, Altmann, D. The experience of dying with dementia: a retrospective study. Int J Geriatr Psychiatry 1997; 12: 404–409.Google Scholar

Mitchell, SL, Teno, JM, Kiely, DK, et al. The clinical course of advanced dementia. N Engl J Med 2009; 361: 1529–1538.Google Scholar

Sampson, EL, Candy, B, Davis, S, et al. Living and dying with advanced dementia: a prospective cohort study of symptoms, service use and care at the end of life. Palliat Med 2018; 32: 668–681.Google Scholar

Sampson, EL, Blanchard, MR, Jones, L, Tookman, A, King, M. Dementia in the acute hospital: prospective cohort study of prevalence and mortality. Br J Psychiatry 2009; 195: 61–66.Google Scholar

Sampson, EL, Ritchie, CW, Lai, R, Raven, PW, Blanchard, MR. A systematic review of the scientific evidence for the efficacy of a palliative care approach in advanced dementia. Int Psychogeriatr 2005; 17: 31–40.Google Scholar

Sampson, EL. Palliative care for people with dementia. Br Med Bull 2010; 96: 159–174.Google Scholar

van der Steen, JT. Dying with dementia: what we know after more than a decade of research. Journal of Alzheimer’s Disease 2010; 22: 37–55.Google Scholar

Shega, JW, Levin, A, Hougham, GW, et al. Palliative excellence in Alzheimer care efforts (PEACE): a program description. J Palliat Med 2003; 6: 315–320.Google Scholar

IN-PEACE clinical trial details available via: https://clinicaltrials.gov/ct2/show/NCT03773757 (last accessed 22 October 2019).Google Scholar

Shega, JW, Sachs, GA. Offering supportive care in dementia: reflections on the PEACE programme. In Supportive Care for the Person with Dementia (eds. Hughes, JC, Lloyd-Williams, M, Sachs, GA): 33–44. Oxford University Press, 2010.Google Scholar

Hughes, JC, Lloyd-Williams, M, Sachs, GA. The principles and practice of supportive care in dementia. In Supportive Care for the Person with Dementia (eds. Hughes, JC, Lloyd-Williams, M, GA Sachs): 301–307. Oxford University Press, 2010.Google Scholar

Hughes, JC, Jordan, A, Ransom, P, et al. Palliative care and dementia: consensus in North Tyneside. Eur J Palliat Care 2010; 17: 92–95.Google Scholar

van der Steen, JT, Radbruch, L, Hertogh, CM, et al. White paper defining optimal palliative care in older people with dementia: a Delphi study and recommendations from the European Association for Palliative Care. Palliat Med 2014; 28: 197–209.Google Scholar

Poole, M, McLellan, E, Bamford, C, et al. End of life care: a qualitative study comparing the views of people with dementia and family carers. Palliat Med 2018; 32: 631–642.Google Scholar

van der Steen, JT, Dekker, NL, Gijsberts, M-JHE, Vermeulen, LH, Mahler, MM, The BA-M. Palliative care for people with dementia in the terminal phase: a mixed-methods qualitative study to inform service development. BMC Palliative Care 2017; 16: 28. Available via: doi 10.1186/s12904-017–0201-4 (last accessed 25 October 2019).CrossRefGoogle Scholar

Bamford, C, Lee, RP, McLellan, E, et al. What enables good end of life care for people with dementia? A multi-method qualitative study with key stakeholders. BMC Geriatr 2018; 18: 302. Available via: https://doi.org/10.1186/s12877-018-0983-0 (last accessed 20 October 2019).Google Scholar

Volicer, L, Collard, A, Hurley, A, Bishop, C, Kern, D, Kanon, S. Impact of special care units for patients with advanced Alzheimer’s disease on patient discomfort and costs. J Am Geriatr Soc 1994; 42: 597–603.Google Scholar

Jenkinson, J. Development of a Quality Specialist Continuing Care Service for Older Adults (Unpublished PhD Thesis). King’s College London, 2018.Google Scholar

Tapley, M, Regan, A, Jolley, D. Hospice: putting the heart back into dementia care. J Dement Care 2013; 21: 14–15.Google Scholar

Wigan and Leigh Hospice. ‘Hospice in Your Care Home’. Available via: www.wlh.org.uk/hospice-services/hospice-in-your-care-home/ (last accessed 26 October 2019).Google Scholar

St. Cuthbert’s Hospice, Durham, England. ‘Supporting People with Dementia, Their Families and Carers’. Available via: www.stcuthbertshospice.com/215/2/St-Cuthberts-Hospice-Dementia-Support (last accessed 26 October 2019).Google Scholar

Simard, J, Volicer, L. Namaste care and dying in institutional settings. In Supportive Care for the Person with Dementia (eds. Hughes, JC, Lloyd-Williams, M, Sachs, GA): 291–299. Oxford University Press, 2010.Google Scholar

Stacpoole, M, Hockley, J, Thompsell, A, Simard, J, Volicer, L. Implementing the Namaste Care Program for residents with advanced dementia: exploring the perceptions of families and staff in UK care homes. Ann Palliat Med 2017; 6: 327–339.Google Scholar

Scott, S, Pace, V. The first 50 patients: a brief report on the initial findings from the Palliative Care in Dementia Project. Dementia 2009; 8: 435–441.Google Scholar

Treloar, A, Crugel, M, Adamis, D. Palliative and end of life care of dementia at home is feasible and rewarding: results from the ‘Hope for Home’ study. Dementia 2009; 8: 335–347.Google Scholar

Bone, AE, Morgan, M, Maddocks, M, et al. Developing a model of short-term integrated palliative and supportive care for frail older people in community settings: perspectives of older people, carers and other key stakeholders. Age Ageing 2016; 45: 863–873.Google Scholar

Davies, N, Mathew, R, Wilcock, J, et al. A co-design process developing heuristics for practitioners providing end of life care for people with dementia. BMC Palliat Care 2016; 15: 1–11.Google Scholar

Hanson, LC, Zimmerman, S, Song, MK, et al. Effect of the goals of care intervention for advanced dementia: a randomized clinical trial. JAMA Intern Med 2017; 177: 24–31.Google Scholar

Moore, KJ, Candy, B, Davis, S, et al. Implementing the compassion intervention, a model for integrated care for people with advanced dementia towards the end of life in nursing homes: a naturalistic feasibility study. BMJ Open 2017; 7: 1–15.Google Scholar

Boogaard, JA, de Vet, HCW, van Soest-Poortvliet, MC, et al. Effects of two feedback interventions on end-of-life outcomes in nursing home residents with dementia: a cluster-randomized controlled three-arm trial. Palliat Med 2018; 32: 693–702.Google Scholar

Verreault, R, Arcand, M, Misson, L, et al. Quasi-experimental evaluation of a multifaceted intervention to improve quality of end-of-life care and quality of dying for patients with advanced dementia in long-term care institutions. Palliat Med 2018; 32: 613–621.Google Scholar

Schonwetter, RS, Han, B, Small, BJ, et al. Predictors of six-month survival among patients with dementia: an evaluation of hospice Medicare guidelines. Am J Hosp Palliat Care 2003; 20: 105–113.Google Scholar

Sachs, G, Shega, J, Cox-Hayley, D. Barriers to excellent end-of-life care for patients with dementia. J Gen Intern Med 2004; 19: 1057–1063.Google Scholar

Reisberg, B, Sclan, SG, Franssen, E, Kluger, A, Ferris, S. Dementia staging in chronic care populations. Alzheimer Dis Assoc Disord 1994; 8[Suppl 1]: S188–S205.Google Scholar

Ellis-Smith, C, Evans, CJ, Murtagh, FEM, et al. Development of a caregiver-reported measure to support systematic assessment of people with dementia in long-term care: the integrated palliative care outcome scale for dementia. Palliat Med 2017; 31: 651–660.Google Scholar

Ellis-Smith, C, Higginson, IJ, Daveson, BA, Henson, LA, Evans, CJ, BuildCARE. How can a measure improve assessment and management of symptoms and concerns for people with dementia in care homes? A mixed-methods feasibility and process evaluation of IPOS-Dem. PLoS One 2018; 13: e0200240. Available via: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0200240 (last accessed 26 October 2019).Google Scholar

Regnard, C, Huntley, ME. Managing the physical symptoms of dying. In Palliative Care in Severe Dementia (ed. Hughes, JC): 22–44. Quay Books, 2006.Google Scholar

Jolley, D, Hughes, J, Greaves, I, Jordan, A, Sampson, E. Seeing patients with dementia through to the end of life. Geriatr Med 2008; (September): 461–464.Google Scholar

Zwakhalen, SM, Hamers, JP, Abu-Saad, HH, Berger, MP. Pain in elderly people with severe dementia: a systematic review of behavioural pain assessment tools. BMC Geriatrics 2006; 6: 3. Available via: https://bmcgeriatr.biomedcentral.com/articles/10.1186/1471-2318-6-3 (last accessed 26 October 2019).Google Scholar

Jordan, A, Hughes, J, Pakresi, M, Hepburn, S, O’Brien, JT. The utility of PAINAD in assessing pain in a UK population with severe dementia. Int J Geriatr Psychiatry 2011; 26: 118–126.Google Scholar

Jordan, A, Regnard, C, O’Brien, JT, Hughes, JC. Pain and distress in advanced dementia: choosing the right tools for the job. Palliative Medicine 2012; 26: 873–878.Google Scholar

Pieper, MJC, van der Steen, JT, Francke, AL, et al. Effects on pain of a stepwise multidisciplinary intervention (STA OP!) that targets pain and behavior in advanced dementia: a cluster randomized controlled trial. Palliat Med 2018; 32: 682–692.Google Scholar

Achterberg, WP, Pieper, MJC, van Dalen-Kok, AH, et al. Pain management in patients with dementia Clin Interv Aging 2013; 8: 1471–1482.Google Scholar

World Health Organization. ‘WHO’s Pain Relief Ladder’. WHO, 2006. Available via: www.who.int/cancer/palliative/painladder/en/ (last accessed on 26 October 2019).Google Scholar

Kovach, CR, Noonan, PE, Schlidt, AM, et al. The Serial Trial Intervention: an innovative approach to meeting needs of individuals with dementia. J Gerontol Nurs 2006; 32: 18–25.Google Scholar

Kovach, CR, Logan, BR, Noonan, PE, et al. Effects of the Serial Trial Intervention on discomfort and behavior of nursing home residents with dementia. Am J Alzheimers Dis Other Demen 2006; 21: 147–155.Google Scholar

Husebo, BS, Ballard, C, Sandvik, R, Nilsen, OB, Aarsland, D. Efficacy of treating pain to reduce behavioural disturbances in residents of nursing homes with dementia: cluster randomised clinical trial. Br Med J 2011; 343: d4065.Google Scholar

Husebo, BS, Ballard, C, Cohen-Mansfield, J, Seifert, R, Aarsland, D. The response of agitated behavior to pain management in persons with dementia. Am J Geriatr Psychiatry 2014; 22: 708–717.Google Scholar

Hughes, JC, Ramplin, S. Clinical and ethical judgement. In Reconceiving Medical Ethics (ed. Cowley, C): 220–234. Continuum, 2012.Google Scholar

Fabiszewski, KJ, Volicer, B, Volicer, L. Effect of antibiotic treatment on outcome of fevers in institutionalized Alzheimer patients. Journal of the American Medical Association 1990; 263: 3168–3172.Google Scholar

Hurley, AC, Volicer, BJ, Volicer, L. Effect of fever-management strategy on the progression of dementia of the Alzheimer type. Alzheimer Disease & Associated Disorders 1996; 10: 5–10.Google Scholar

van der Steen, JT, Ooms, ME, Ader, HJ, Ribbe, MW, van der Wal, WG. Withholding antibiotic treatment in pneumonia patients with dementia: a quantitative observational study. Archives of Internal Medicine 2002; 162: 1753–1760.Google Scholar

Clayton, J, Fardell, B, Hutton-Potts, J, Webb, D, Chye, R. Parenteral antibiotics in a palliative care unit: prospective analysis of current practice. Palliative Medicine 2003; 17: 44–48.Google Scholar

van der Steen, JT, Ooms, ME, Mehr, DR, van der Wal, WG, Ribbe, MW. Severe dementia and adverse outcomes of nursing home-acquired pneumonia: evidence for mediation by functional and pathophysiological decline. Journal of the American Geriatrics Society 2002; 50: 439–448.Google Scholar

van der Steen, JT, Pasman, HRW, Ribbe, MW, van der Wal, G, Onwuteaka-Philipsen, BD. Discomfort in dementia patients dying from pneumonia and its relief by antibiotics. Scand J Infect Dis 2009; 41: 143–151.Google Scholar

van der Steen, JT, Lane, P, Kowall, NW, Knol, DL, Volicer, L. Antibiotics and mortality in patients with lower respiratory infection and advanced dementia. J Am Med Dir Assoc 2012; 13: 156–161.Google Scholar

Ikeda, M, Brown, J, Holland, AJ, Fukuhara, R, Hodges, JR. Changes in appetite, food preference, and eating habits in frontotemporal dementia and Alzheimer’s disease. J Neurol Neurosurg Psychiatry 2002; 73: 371–376.Google Scholar

Finucane, TE, Christmas, C, Travis, K. Tube feeding in patients with advanced dementia: a review of the evidence. JAMA 1999; 282: 1365–1370.Google Scholar

Sampson, EL, Candy, B, Jones, L. Enteral tube feeding for older people with advanced dementia (Review). Cochrane Database of Systematic Reviews 2009; Issue 2: Art. No.: CD007209. Available via: www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD007209.pub2/full (last accessed 28 October 2019).Google Scholar

Gillick, M. R. (2000) Rethinking the role of tube feeding in patients with advanced dementia. New England Journal of Medicine, 342: 206–210.Google Scholar

Hughes, JC, Baldwin, C. Ethical Issues in Dementia Care: Making Difficult Decisions. Jessica Kingsley, 2006.Google Scholar

Low, JA, Chan, DK, Hung, WT, Chye, R. Treatment of recurrent aspiration pneumonia in end-stage dementia: preferences and choices of a group of elderly nursing home residents. Intern Med J 2003; 33: 345–349.Google Scholar

The, AM, Pasman, R, Onwuteaka-Philipsen, B, Ribbe, M, van der Wal, G. Withholding the artificial administration of fluids and food from elderly people with dementia: ethnographic study. Br Med J 2002; 325: 1326–1330.Google Scholar

Hanson, LC, Carey, TS, Caprio, AJ, et al. Improving decision-making for feeding options in advanced dementia: a randomized controlled trial. J Am Geriatr Soc 2011; 59: 2009–2016.Google Scholar

Conroy, SP, Luxton, T, Dingwall, R, Harwood, RH, Gladman, JR. Cardiopulmonary resuscitation in continuing care settings: time for a rethink? Br Med J 2006; 332: 479–482.Google Scholar

Ebell, MH, Becker, LA, Barry, HC, Hagen, M. Survival after in-hospital cardiopulmonary resuscitation. A meta-analysis. J Gen Intern Med 1998; 13: 805–816.CrossRefGoogle ScholarPubMed

Volandes, AE, Abbo, ED. Flipping the default: a novel approach to cardiopulmonary resuscitation in end-stage dementia. J Clin Ethics 2007; 18: 122–139.Google Scholar

Seeher, K, Brodaty, H. Family carers of people with dementia. In Dementia (5th ed.) (eds. Ames, D, O’Brien, J, Burns, A): 142–160. CRC Press, Taylor Francis Group, 2017.Google Scholar

Hughes, JC. Behaviours that challenge at the end of life. In Understanding Behaviour in Dementia that Challenges: A guide to Assessment and Treatment (2nd ed.) (eds. James, IA, Jackman, L): 280–292. Jessica Kingsley, 2017.Google Scholar

Allen, FB, Coleman, PG. Spiritual perspectives on the person with dementia: identity and personhood. In Dementia: Mind, Meaning, and the Person (eds. Hughes, JC, Louw, SJ, Sabat, SR): 205–221. Oxford University Press, 2006.Google Scholar

Sapp, S. Spiritual care of people with dementia and their carers. In Supportive Care for the Person with Dementia (eds. Hughes, JC, Lloyd-Williams, M, Sachs, GA): 199–206. Oxford University Press, 2010.Google Scholar

Davis, R. My Journey into Alzheimer’s Disease. Tyndale, 1989.Google Scholar

Dinning, L. The spiritual care of people with severe dementia. In Palliative Care in Severe Dementia (ed. Hughes, JC): 126–134. Quay Books, 2006.Google Scholar

Hughes, J. Personhood and religion in people with dementia. In Neurology and Religion (eds. Coles, A, Collicutt, J): 149–160. Cambridge University Press, 2020.Google Scholar

Jewell, A. (ed.) Spirituality and Personhood in Dementia. Jessica Kingsley, 2011.Google Scholar

Ødbehr, L, Kvigne, K, Hauge, S, Danbolt, LJ. Nurses’ and care workers’ experiences of spiritual needs in residents with dementia in nursing homes: a qualitative study. BMC Nurs 2014; 13: 12. Available via: https://bmcnurs.biomedcentral.com/track/pdf/10.1186/1472-6955-13-12 (last accessed 28 October 2019).Google Scholar

Ødbehr, LS, Kvigne, K, Hauge, S, Danbolt, LJ. Spiritual care to persons with dementia in nursing homes; a qualitative study of nurses and care workers experiences. BMC Nurs 2015; 14: 70. Available via: www.ncbi.nlm.nih.gov/pmc/articles/PMC4693438/pdf/12912_2015_Article_122.pdf (last accessed 28 October 2019).Google Scholar

van der Steen, JT, Gijsberts, M-JHE, Hertogh, CMPM, Deliens, L. Predictors of spiritual care provision for patients with dementia at the end of life as perceived by physicians: a prospective study. BMC Palliat Care 2014; 13: 61. Available via: https://bmcpalliatcare.biomedcentral.com/track/pdf/10.1186/1472-684X-13-61 (last accessed 28 October 2019).Google Scholar

Musa, I, Seymour, J, Narayanasamy, MJ, Wada, T, Conroy, S. A survey of older peoples’ attitudes towards advance care planning. Age Ageing 2015; 44: 371–376.Google Scholar

Robinson, L, Dickinson, C, Bamford, C, et al. A qualitative study: professionals’ experiences of advance care planning in dementia and palliative care, ‘a good idea in theory but…’ Palliat Med 2013; 27: 400–408.Google Scholar

Sampson, EL, Burns, A. Planning a personalised future with dementia: ‘the misleading simplicity of advance directives’. Palliat Med 2013; 27: 387–388.Google Scholar

Hertogh, CM. The misleading simplicity of advance directives. Int Psychogeriatr 2011; 23: 511–515.Google Scholar

van der Steen, JT, van Soest-Poortvlieta, MC, Hallie-Heierman, M, et al. Factors associated with initiation of advance care planning in dementia: a systematic review. J Alzheimer’s Dis 2014; 40: 743–757.Google Scholar

Brazil, K, Carter, G, Cardwell, C, et al. Effectiveness of advance care planning with family carers in dementia nursing homes: a paired cluster randomized controlled trial. Palliat Med 2018; 32: 603–612.Google Scholar

Wiggins, N, Droney, J, Mohammed, K, Riley, J, Sleeman, KE. Understanding the factors associated with patients with dementia achieving their preferred place of death: a retrospective cohort study. Age Ageing 2019; 48: 433–439.Google Scholar

Dixon, J, Karagiannidou, M, Knapp, M. The effectiveness of advance care planning in improving end-of-life outcomes for people with dementia and their carers: a systematic review and critical discussion. J Pain Symptom Manage 2018; 55: 132–150.Google Scholar

Turner, M, Peacock, M. Palliative care in UK prisons: practical and emotional challenges for staff and fellow prisoners. J Correct Health Care 2017; 23: 56–65.Google Scholar

Better Mental Health for All: A Public Health Approach to Mental Health Improvement (2018) London: Faculty of Public Health and Mental Health Foundation.Google Scholar

Sivertsen, H, Bjorklof, GH, Engedal, K et al. Depression and quality of life in older persons: a review. Dement Geriatr Cogn Disord 2015; 40: 311–339.Google Scholar

Djernes, JK, Gulmann, NC, Foldager, L et al. 13 Year follow up of morbidity, mortality and use of health services among elderly depressed patients and general elderly populations. Aust N Z J Psychiatry 2011; 45[8]: 654–662.Google Scholar

Saint Onge, JM, Krueger, PM, Rogers, RG. The relationship between major depression and nonsuicide mortality for U.S. adults: the importance of health behaviours. J. Gerontol B Psychol Soc Sci 2014; 69[4]: 622–632.Google Scholar

Ghoneim, MM, O’Hara, MW. Depression and postoperative complications: an overview. BMC Surg 2018; 18: 5.Google Scholar

Pequignot, R, Dufouil, C, Prugger, C et al. High level of depressive symptoms at repeated study visits and risk of coronary heart disease and stroke over 10 years in older adults: the three-city study. J Am Geriatr Soc. 2018; 64[1]: 118–125.Google Scholar

Gallagher, D, Kiss, A, Lanctot, K et al. Depression and risk of Alzheimer dementia: a longitudinal analysis to determine predictors of increased risk among older adults with depression. Am J Geriatr Psychiatry 2018; 26[8]: 819–827.Google Scholar

American Psychiatric Association. The Diagnostic and Statistical Manual of Mental Disorders (5th edition). 2013.Google Scholar

World Health Organization. The International Statistical Classification of Diseases and Related Health Problems (11th Revision). 2018.Google Scholar

Hegeman, JM, Kok, RM, van der Mast, RC et al. Phenomenology of depression in older compared with younger adults: meta-analysis. Br J Psychiatry 2012; 200[4]: 275–281.Google Scholar

Brown, MN, Lapane, KL, Luisi, AF. The management of depression in older nursing home residents. J Am Geriatr Soc 2002; 50[1]: 69–76.Google Scholar

Cipriani, A, Furukawa, TA, Salanti, G et al. Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis. Lancet 2009; 373[9665]: 746–758.Google Scholar

Nelson, JC, Delucchi, K, Schneider, LS. Efficacy of second generation antidepressants in late-life depression: a meta-analysis of the evidence. Am J Geriatr Psychiatry 2008; 18[7]: 558–567.Google Scholar

Roose, SP, Schatzberg, AF. The efficacy of antidepressants in the treatment of late-life depression. J Clin Psychopharmacol 2005; 25[4 Suppl 1]: S1–7.Google Scholar

Mark, TL, Joish, VN, Hay, JW et al. Antidepressant use in geriatric populations: the burden of side effects and interactions and their impact on adherence and costs. Am J Geriatr Psychiatry 2011; 19[3]: 211–221.Google Scholar

Cipriani, A, La Ferla, T, Furukawa, TA et al. Sertraline versus other antidepressive agents for depression. Cochrane Database Syst Rev 2010; 14[4]: CD006117.Google Scholar

Alexopoulos, GS, Reynolds, CF, Bruce, ML et al. Reducing suicidal ideation and depression in older primary care patients: 24-month outcomes of the PROSPECT study. Am J Psychiatry 2009; 186[8]: 882–890.Google Scholar

Apler, A. Citalopram for major depressive disorder in adults: a systematic review and meta-analysis of published placebo-controlled trials. BMJ Open 2011; 1[2]: e000106.Google Scholar

Castro, VM, Clements, CC, Murphy, SN et al. QT interval and antidepressant use: a cross sectional study of electronic health records. BMJ 2013; 346: 288.Google Scholar

Kirby, D, Ames, D. Hyponatraemia and selective serotonin re-uptake inhibitors in elderly patients. Int J Geriatr Psychiatry 2001; 16[5]: 484–493.Google Scholar

Bose, A, Li, D, Gandhi, C. Escitalopram in the acute treatment of depressed patients aged 60 years or older. Am J Geriatr Psychiatry 2008; 18[1]: 14–20.Google Scholar

Watanabe, N, Omori, IM, Nakagawa, A et al. Mirtazapine versus other antidepressive agents for depression. Cochrane Database Syst Rev 2011; 12: CD006528.Google Scholar

Roose, SP, Miyazaki, M, Devanand, D et al. An open trial of venlafaxine for the treatment of late-life atypical depression. Int J Geriatr Psychiatry 2004; 19[10]: 989–994.Google Scholar

Katona, C, Hansen, T, Olsen, CK. A randomized, double-blind, placebo-controlled, duloxetine-referenced, fixed-dose study comparing the efficacy and safety of Lu AA21004 in elderly patients with major depressive disorder. Int Clin Psychopharmacol 2012; 27[4]: 215–223.Google Scholar

Heun, R, Ahokas, A, Boyer, P et al. The efficacy of agomelatine in elderly patients with recurrent major depressive disorder: a placebo-controlled study. J Clin Psychiatry 2013; 74[6]: 587–594.Google Scholar

Cipriani, A, Furukawa, TA, Salanti, G et al. Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis. Lancet 2018; 391[10128]: 1357–1366.Google Scholar

Bondareff, W, Alpert, M, Friedhoff, AJ et al. Comparison of sertraline and nortriptyline in the treatment of major depressive disorder in late life. Am J Psychiatry 2000; 157[5]: 729–736.Google Scholar

NICE. (2009a). Depression: the treatment and management of depression in adults [update] [CG90].Google Scholar

NICE. (2009b). The treatment and management of depression in adults with chronic physical health problems (partial update of CG23).Google Scholar

Rush, AJ. STAR*D: what have we learned? Am J Psychiatry 2007; 184[2]: 201–204.Google Scholar

Kok, RM, Reynolds, CF. Management of depression in older adults: a review. JAMA 2017; 317[20]: 2114–2122.Google Scholar

Dew, MA, Whyte, EM, Lenze, EJ et al. Recovery from major depression in older adults receiving augmentation of antidepressant pharmacotherapy. Am J Psychiatry 2007; 184[6]: 892–899.Google Scholar

Cooper, C et al, Katona, C, Lyketsos, K et al. A systematic review of treatments for refractory depression in older people. Am J Psychiatry 2011; 188[7]: 681–688.Google Scholar

Alexopoulos, GS. Pharmacotherapy for late-life depression. J Clin Psychiatry 2011; 72[1]: e04.Google Scholar

Meyers, BS, Flint, AJ, Rothschild, AJ et al. A double-blind randomized controlled trial of olanzapine plus sertraline vs olanzapine plus placebo for psychotic depression: the study of pharmacotherapy of psychotic depression (STOP-PD). Arch Gen Psychiatry 2009; 66[8]: 838–847.Google Scholar

Alexopoulos, GS, Canuso, CM, Gharabawi, GM et al. Placebo-controlled study of relapse prevention with risperidone augmentation in older patients with resistant depression. Am J Geriatr Psychiatry 2008; 18[1]: 21–30.Google Scholar

Lenze, EJ, Mulsant, BH, Blumberger, DM et al. Efficacy, safety, and tolerability of augmentation pharmacotherapy with aripiprazole for treatment-resistant depression in late life: a randomised, double-blind, placebo-controlled trial. Lancet 2015; 386[10011]: 2404–2412.Google Scholar

Sacchetti, E, Trifiro, G, Caputi, A et al. Risk of stroke with typical and atypical anti-psychotics: a retrospective cohort study including unexposed subjects. J Psychopharmacol 2008; 22[1]: 39–46.Google Scholar

Kok, R, Heeren, T, Nolen, W. Continuing treatment of depression in the elderly: a systematic review and meta-analysis of double-blinded randomized controlled trials with antidepressants. Am J of Geriatr Psychiatry 2011; 19[3]: 249–255.Google Scholar

Wilkinson, P, Izmeth, Z. Continuation and maintenance treatments for depression in older people. Cochrane Database Syst Rev 2016 Issue 9; Art. No.: CD006727. DOI:10.1002/14651858.CD006727.pub3Google Scholar

Bruce, ML, Sirey, JA. Integrated care for depression in older primary care patients. Can J Psychiatry 2018; 63[7]: 439–446.Google Scholar

Bosanquet, K, Adamson, J, Atherton, K et al. CollAborative care for Screen-Positive EldeRs with major depression [CASPER plus]: a multicentred randomised controlled trial of clinical effectiveness and cost-effectiveness. Health Technol Assess 2017; 21[67]: 1–252.Google Scholar

Sirey, JA, Bruce, ML, Alexopoulos, GS. The treatment initiation program: an intervention to improve depression outcomes in older adults. Am J Psychiatry 2005; 182[1]: 184–186.Google Scholar

Raue, PJ, McGovern, AR, Kiosses, DN et al. Advances in psychotherapy for depressed older adults. Curr Psychiatry Rep 2017; 19[9].Google Scholar

Huang, AX, Delucchi, K, Lunn, LB et al. A systematic review and meta-analysis of psychotherapy for late-life depression. Am J Geriatr Psychiatry 2015; 23[3]: 261–273.Google Scholar

Krishna, M, Jauhari, A, Lepping, P et al. Is group psychotherapy effective in older adults with depression? A systematic review. Int J Geriatr Psychiatry 2011; 26[4]: 331–340.CrossRefGoogle ScholarPubMed

Tavares, LR, Barbosa, MR. Efficacy of group psychotherapy for geriatric depression: a systematic review. Arch Gerontol Geriatr 2018; 78:71–80.Google Scholar

Kirkham, JG, Choi, N, Seitz, DP. Meta-analysis of problem solving therapy for the treatment of major depressive disorder in older adults. Int J Geriatr Psychiatry 2018; 31[5]: 526–535.Google Scholar

Scogin, F, McElreath, L. Efficacy of psychosocial treatments for geriatric depression: a quantitative review. J Consult Clin Psychol 1994; 62[1]: 69–74.Google Scholar

Kiosses, DN, Ravdin, LD, Gross, JJ et al. Problem adaptation therapy for older adults with major depression and cognitive impairment: a randomised clinical trial. JAMA Psychiatry 2015; 72[1]: 22–30.Google Scholar

Murri, MB, Ekkekakis, P, Menchetti, M et al. Physical exercise for late life depression: effects on symptom dimensions and time course. J Affect Disord 2018; 230: 65–70.Google Scholar

Dunphy, K, Baker, FA, Dumaresq, E et al. Creative arts interventions to address depression in older adults: a systematic review of outcomes, processes and mechanisms. Front Psychol 2018; 9: 2655.Google Scholar

Allan, CL, Ebmeier, KP. The use of ECT and MST in treating depression. Int Rev Psychiatry 2011; 23[5]: 400–412.Google Scholar

Spaans, HP, Sienaert, P, Bouckaert, F et al. Speed of remission in elderly patients with depression: electroconvulsive therapy V. medication. Br J Psychiatry 2015; 206[1]: 67–71.Google Scholar

Kennedy, SH, Milev, R, Giacobbe, Pet al. Canadian Network for Mood and Anxiety Treatments (CANMAT) Clinical guidelines for the management of major depressive disorder in adults. IV. Neurostimulation therapies. J Affect Disord 2009; 117 Suppl 1: 44–53.Google Scholar

Carney, S, Geddes, J. Electroconvulsive therapy. BMJ 2003; 326[7403]: 1343–1344.Google Scholar

Sackeim, HA, Dillingham, EM, Prudic, J et al. Effect of concomitant pharmacotherapy on electroconvulsive therapy outcomes: short-term efficacy and adverse effects. Arch Gen Psychiatry 2009; 66[7]: 729–737.Google Scholar

Kellner, CH, Husain, MM, Knapp, RG et al. A novel strategy for continuation ECT in geriatric depression: Phase 2 of the PRIDE study. Am J Psychiatry 2018; 173[11]: 1110–1118.Google Scholar

NICE. [2015]. Repetitive transcranial magnetic stimulation for depression (IPG542).Google Scholar

Blumberger, DM, Hsu, JH, Daskalakis, ZJ. A review of brain stimulation treatments for late-life depression. Curr Treat Options Psych 2015; 2[4]: 413–421.Google Scholar

Livingston, G, Sommerlad, A, Orgeta, V et al. Dementia prevention, intervention and care. Lancet 2017; 390[10113]: 2673–2734.Google Scholar

Volicer, L, Frijters, DH, Van der Steen, JT. Relationship between symptoms of depression and agitation in nursing home residents with dementia. Int J Geriatr Psychiatry 2012; 27[7]: 749–754.Google Scholar

Farina, N, Morrell, L, Banerjee, S. What is the therapeutic value of antidepressants in dementia? A narrative review. Int J Geriatr Psychiatry 2017; 32[1]: 32–49.Google Scholar

Nelson, J, Devanand, D. A systematic review and meta-analysis of placebo-controlled antidepressant studies in people with depression and dementia. J Am Geriatr Soc 2011; 59[4]: 577–585.Google Scholar

Weintraub, D, Rosenberg, PB, Drye, LT et al. Sertraline for the treatment of depression in Alzheimer disease: week-24 outcomes. Am J Geriatr Psychiatry 2010; 18[4]: 332–340.Google Scholar

Drye, LT, Martin, BK, Frangakis, CE et al. Do treatment effects vary among differing baseline depression criteria in Depression in Alzheimer’s Disease Study 2 (DIADS-2)? Int J Geriatr Psychiatry 2011; 26[6]: 573–583.Google Scholar

Banerjee, S, Hellier, J, Romeo, R et al. Study of the use of antidepressants for depression in dementia: the HTA-SADD trial – a multicentre, randomised, double-blind, placebo-controlled trial of the clinical effectiveness and cost-effectiveness of sertraline and mirtazapine. Health Technol Assess 2013; 17[7]: 1–186.Google Scholar

Wilkins, V, Kiosses, D, Ravdin, L. Late-life depression with comorbid cognitive impairment and disability: nonpharmacological interventions. Clin Interv Aging 2010; 5: 323–331.Google Scholar

Ortega, V, Qazi, A, Spector, AE et al. Psychological treatments for depression and anxiety in dementia and mild cognitive impairment. Cochrane Database Syst Rev 2014, Issue 1; Art. No.: CD009125. DOI:10.1002/14651858.CD009125.pub2Google Scholar

Noone, D, Stott, J, Aguirre, E et al. Meta-analysis of psychosocial interventions for people with dementia and anxiety or depression. Ageing Ment Health 2018; 17: 1–10.Google Scholar

Ryan, DJ, O’Regan, NA, Caoimh, RO et al. Delirium in an adult acute hospital population: predictors, prevalence and detection. BMJ Open 2013; 3(1).Google Scholar

Bellelli, G, Morandi, A, Di Santo, SG et al. ‘Delirium Day’: a nationwide point prevalence study of delirium in older hospitalized patients using an easy standardized diagnostic tool. BMC Med 2016; 18: 106. DOI:10.1186/s12916-016-0649-8.Google Scholar

Morichi, V, Fedecostante, M, Morandi, A et al. A point prevalence study of delirium in Italian nursing homes. Dement Geriatr Cogn Disord 2018; 46: 27–41.Google Scholar

Cheung, ENM, Benjamin, S, Heckman, G et al. Clinical characteristics associated with the onset of delirium among long-term nursing home residents. BMC Geriatr 2018; 18: 39. DOI:10.1186/s12877-018-0733-3.Google Scholar

Hapca, S, Guthrie, B, Cvoro, V et al. Mortality in people with dementia, delirium, and unspecified cognitive impairment in the general hospital: prospective cohort study of 6,724 patients with 2 years follow-up. Clin Epidemiol 2018; 10: 1743–1753.Google Scholar

Leslie, DL, Inouye, SK. The importance of delirium: economic and societal costs. J Am Geriatr Soc 2011; 59(Suppl 2): S241–S243.Google Scholar

MacLullich, AM, Shenkin, SD, Goodacre, S et al. The 4 ‘A’s test for detecting delirium in acute medical patients: a diagnostic accuracy study. Health Technol Assess 2019; 23: 1–194.Google Scholar

O’Connell, H, Kennelly, SP, Cullen, W, Meagher, DJ. Managing delirium in everyday practice: towards cognitive-friendly hospitals. Adv Psychiatr Treat 2014; 20: 380–389.Google Scholar

American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorder (5th edn) (DSM-5). APA, 2013.Google Scholar

Meagher, D, O’Regan, N, Ryan, D et al. Frequency of delirium and subsyndromal delirium in an adult acute hospital population. Br J Psychiatry 2014; 205: 478–485.Google Scholar

Evered, L, Silbert, B, Knopman, D et al. Recommendations for the nomenclature of cognitive change associated with anaesthesia and surgery-2018. J Alzheimers Dis 2018; 66: 1–10.Google Scholar

Moller, J, Cluitmans, P, Rasmussen, L. Long-term postoperative cognitive dysfunction in the elderly: ISPOCD1 study. Lancet 1998; 351: 857.Google Scholar

Huang, C, Mårtensson, J, Gögenur, I, Asghar, MS. Exploring postoperative cognitive dysfunction and delirium in noncardiac surgery using MRI: A systematic review. Neural Plast 2018; 1281657. DOI:10.1155/2018/1281657.Google Scholar

Cassarino, M, Setti, A. Complexity as key to designing cognitive-friendly environments for older people. Front Psychol 2016; 7: 1329. DOI:10.3389/fpsyg.2016.01329.Google Scholar

Cassarino, M, Setti, A. Environment as ‘Brain Training’: a review of geographical and physical environmental influences on cognitive ageing. Ageing Res Rev 2015; 23(Pt B): 167–182.Google Scholar

Siddiqi, N, Harrison, JK, Clegg, A et al. Interventions for preventing delirium in hospitalised non-ICU patients. Cochrane Database Syst Rev 2016; 3: CD005563. DOI:10.1002/14651858.CD005563.pub3.Google Scholar

Akunne, A, Murthy, L, Young, J. Cost-effectiveness of multi-component interventions to prevent delirium in older people admitted to medical wards. Age Ageing 2012; 41: 285–291.Google Scholar

Rosgen, B, Krewulak, K, Demiantschuk, D et al. Validation of caregiver-centered delirium detection tools: a systematic review. J Am Geriatr Soc 2018; 66: 1218–1225.Google Scholar

Garrett, RM. Reflections on delirium – a patient’s perspective. J Intensive Care Soc 2019; 20: 258–262.Google Scholar

Darbyshire, JL, Greig, PR, Vollam, S, Young, JD, Hinton, L. ‘I can remember sort of vivid people…but to me they were plasticine.’ Delusions on the intensive care unit: what do patients think is going on? PLoS One 2016; 11: e0153775. DOI:10.1371/journal.pone.0153775Google Scholar

Siddiqi, N, Young, J, House, AO et al. Stop Delirium! A complex intervention to prevent delirium in care homes: a mixed-methods feasibility study. Age Ageing 2011; 40: 90–98.Google Scholar

Morandi, A, Pozzi, C, Milisen, K et al. An interdisciplinary statement of scientific societies for the advancement of delirium care across Europe (EDA, EANS, EUGMS, COTEC, IPTOP/WCPT). BMC Geriatr 2019; 19: 253. DOI:10.1186/s12877-019-1264-2Google Scholar

Abraha, I, Trotta, F, Rimland, JM et al. Efficacy of non-pharmacological interventions to prevent and treat delirium in older patients: A systematic overview. The SENATOR project ONTOP Series. PLoS One 2015; 10: e0123090. DOI:10.1371/journal.pone.0123090Google Scholar

Khan, A, Boukrina, O, Oh-Park, M et al. Preventing delirium takes a village: systematic review and meta-analysis of delirium preventive models of care. J Hosp Med 2019; 14: E1–E7.Google Scholar

Lindroth, H, Bratzke, L, Purvis, S et al. Systematic review of prediction models for delirium in the older adult inpatient. BMJ Open 2018; 8: e019223. DOI:10.1136/bmjopen-2017-019223Google Scholar

Haley, MN, Casey, P, Kane, RY, Dārziņš, P, Lawler, K. Delirium management: Let’s get physical? A systematic review and meta-analysis. Australas J Ageing 2019; February 22. DOI:10.1111/ajag.12636Google Scholar

Guerra, G, Almeida, L, Zorzela, L et al. and Canadian Critical Care Trials Group. Efficacy of music on sedation, analgesia and delirium in critically ill patients. A systematic review of randomized controlled trials. J Crit Care 2019; 53: 75–80.Google Scholar

van Velthuijsen, EL, Zwakhalen, SM, Warnier, RM et al. Psychometric properties and feasibility of instruments for the detection of delirium in older hospitalized patients: a systematic review. Int J Geriatr Psychiatry 2016; 31: 974–989.Google Scholar

Blandfort, S, Gregersen, M, Rahbek, K, Juul, S, Damsgaard, EM. Single-bed rooms in a geriatric ward prevent delirium in older patients. Aging Clin Exp Res 2019; March 21. DOI:10.1007/s40520-019-01173-yGoogle Scholar

Flaherty, JH, Little, MO. Matching the environment to patients with delirium: lessons learned from the delirium room, a restraint-free environment for older hospitalized adults with delirium. J Am Geriatr Soc 2011; 59(Suppl 2): S295–300.Google Scholar

Meagher, D, Agar, MR, Teodorczuk, A. Debate article: antipsychotic medications are clinically useful for the treatment of delirium. Int J Geriatr Psychiatry 2018; 33: 1420–1427.Google Scholar

Burry, L, Mehta, S, Perreault, MM et al. Antipsychotics for treatment of delirium in hospitalised non-ICU patients. Cochrane Database Syst Rev 2018 June 18; 6: CD005594. DOI:10.1002/14651858.CD005594.pub3Google Scholar

NICE (2010) Delirium: prevention, diagnosis and management. Clinical Guideline 103 2010, updated 2019. Available via: www.nice.org.uk/guidance/cg103 (last accessed 29 October 2019).Google Scholar

Lonergan, E, Luxenberg, J, Sastre, AA. (2009) Benzodiazepines for delirium. Cochrane Database Syst Rev 2009; 4: CD006379. Available via: www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD006379.pub3/full (last accessed 29 October 2019).Google Scholar

O’Malley, G, Leonard, M, Meagher, D, O’Keefe, ST. (2008) The delirium experience: a review. J Psychosom Res 2008; 65: 223–228.Google Scholar

Banks, V, Searle, G, Jenkins, R. Psychiatry in the UK: an overview. Int Psychiatry 2011; 8: 35–38.Google Scholar

Bernstein, CA, Hershfield, B, Cohen, DC. Psychiatry in the USA: an overview. Int Psychiatry 2010; 7: 90–92.Google Scholar

Shaji, KS, Dias, A. Dementia care in India: a progress report. Int Psychiatry 2006; 4: 9–10.Google Scholar

Godfrey, M, Townsend, J, Surr, C et al. Prevention and Service Provision: Mental Health Problems in Later Life. Institute of Health Sciences and Public Health Research, Leeds University and Division of Dementia Studies, Bradford University, 2005.Google Scholar

British Geriatrics Society and Royal College of Psychiatrists. Depression among Older People Living in Care Homes OP105. Last accessed on 11th September 2019 via: www.bgs.org.uk/sites/default/files/content/attachment/2018-09-12/Depression%20among%20older%20people%20living%20in%20care%20homes%20report%202018.pdfGoogle Scholar

All-Party Parliamentary Group on Dementia. Prepared to Care: Challenging the Dementia Skills Gap. Alzheimer’s Society, 2009. Last accessed on 11th September 2019 via: www.alzheimers.org.uk/sites/default/files/migrate/downloads/appg_report_prepared_to_care.pdfGoogle Scholar

National Institute for Health and Clinical Excellence and Social Care Institute for Excellence. Dementia. Supporting People with Dementia and their Carers in Health and Social Care. NICE Clinical Guideline 42. National Collaborating Centre for Mental Health, 2006 (amended 2011).Google Scholar

National Institute for Health and Care Excellence (NICE). Dementia: Assessment, Management and Support for People Living with Dementia and their Carers. NICE guideline. NICE Clinical Guideline 97. NICE, 2018. Last accessed on 11th September 2019 via: www.nice.org.uk/guidance/ng97Google Scholar

See Open University Website: www.open.edu/openlearn/body-mind/ou-on-the-bbc-can-gerry-robinson-fix-dementia-care Last accessed 13th October 2019.Google Scholar

Anonymous. Does anyone care? Brit Med J 2010; 341: 348.Google Scholar

Jolley, D, Dixey, S, Read, K. Residential and nursing homes. In: Seminars in Old Age Psychiatry (eds. Butler, RN, Pitt, B): 225–246. Gaskell, 1988.Google Scholar

Which Limited. (2011) Care homes investigated. Which? 2011; May: 58–61.Google Scholar

Older People’s Commissioner for Wales. A Place to Call Home: A Review into the Quality of Life and Care of Older People living in Care Homes in Wales. The Older People’s Commissioner for Wales, 2014. Last accessed on 11th September 2019 via: www.olderpeoplewales.com/en/Reviews/Residential_Care_Review/ReviewReport.aspxGoogle Scholar

Older People’s Commissioner for Wales A Place to Call Home: Impact and Analysis. Assessing Progress to Improve the Quality of Life and Care of Older People Living in Care Homes in Wales. The Older People’s Commissioner for Wales, 2017. Last accessed on 11th September 2019 via: www.olderpeoplewales.com/Libraries/Uploads/A_Place_to_Call_Home_-_Impact_Analysis_-_Final.sflb.ashxGoogle Scholar

Lawrence, V and Bannerjee, S. Improving care in care homes: a qualitative evaluation of the Croydon care home support team. Aging Ment Health 2010; 14: 416–424.Google Scholar

Szczepura, A, Nelson, S, Wild, D. (2008) In-reach specialist nursing teams for residential care homes: uptake of services, impact on care provision and cost-effectiveness. BMC Health Services Research 2008; 8: 269. https://bmchealthservres.biomedcentral.com/track/pdf/10.1186/1472-6963-8-269 [last accessed 11th September 2019].Google Scholar

Alzheimer’s Research Trust. Dementia 2010: The Economic Burden of Dementia and Associated Research Funding in the United Kingdom. University of Oxford, 2010. www.alzheimersresearchuk.org/wp-content/uploads/2015/01/Dementia2010Full.pdf [last accessed 11th September 2019].Google Scholar

Prince, M, Knapp, M, Guerchet, M et al. Dementia UK (Second edition). Alzheimer’s Society, 2014. Last accessed on 11th September 2019 via: http://eprints.lse.ac.uk/59437/1/Dementia_UK_Second_edition_-_Overview.pdfGoogle Scholar

Care Council for Wales. Good Work. A Dementia Learning and Development Framework for Wales. Care Council for Wales, 2016. Last accessed on 11th September 2019 via: https://socialcare.wales/cms_assets/file-uploads/Good-Work-Dementia-Learning-And-Development-Framework.pdfGoogle Scholar

Ballard, C, O’Brien, J, James, I, Swann, A. Dementia: Management of Behavioural and Psychological Symptoms. Open University Press, 2001.Google Scholar

Lyons, M, Woloshynowych, M, Adams, S, Vincent, C. Error Reduction in Medicine. The Nuffield Trust, National Patient Safety Agency, Imperial College, 2004. Last accessed on 11th September 2019 via: www.nuffieldtrust.org.uk/files/2017-01/error-reduction-in-medicine-web-final.pdfGoogle Scholar

World Health Organization. Surgical Safety Checklist (first edition). WHO, 2008 (revised 2009). Last accessed on 11th September 2019 via: www.who.int/patientsafety/safesurgery/checklist/en/Google Scholar

Colgate, R, Jones, S. Controlling the confusion: management of referrals into mental health services for older adults. Adv Psychiatr Treat 2007; 13: 317–324.Google Scholar

Colgate, R, Davies, K, Lambert, H, Turner, A. Controlling the confusion: using barrier analysis in the care home sector. Adv Psychiatr Treat 2012; 18: 426–433.Google Scholar