Clinical Case Studies in Long-Term Care Psychiatry Navigating Common Mental Health Challenges in Geriatric Care
Book contents
- Clinical Case Studies in Long-Term Care Psychiatry
- Clinical Case Studies in Long-Term Care Psychiatry
- Copyright page
- Contents
- Preface
- Section 1 Neurocognitive Disorders
- Case 2 “I Think I Hit My Head”
- Case 3 “It’s like She’s a Different Person”
- Case 4 “I Am Tired All the Time”
- Case 5 “I Am Okay”
- Case 6 “Leave Me Alone”
- Case 7 “I Am Fine”
- Case 8 “Those Children Are Cute”
- Case 9 “Those Terrible Men Have Left”
- Case 10 “I Saw the Heavenly Gates”
- Case 11 “Leave Me Alone”
- Section 2 Mood Disorders
- Case 13 “My Mom Looks Like a Zombie!”
- Case 14 “My Soul Is in England”
- Case 15 “I Feel Terrible”
- Case 16 “I Don’t Care”
- Case 17 “I Feel Very Lonely”
- Case 18 “I Don’t Feel Right”
- Case 19 “I Am Feeling Great”
- Case 20 “I Am Staying Here Illegally”
- Section 3 Psychotic Disorders
- Case 22 “He Just Won’t Get Up”
- Case 23 “My Body Is Being Taken over by a Fungus!”
- Case 24 “This Is Humiliating”
- Case 25 “I Want to Go Home”
- Case 26 “I Am a Worrier”
- Case 27 “Get out of My House”
- Section 4 Anxiety and Related Disorders
- Case 29 “My Vision Has Been Worsening in the Last Two Weeks”
- Case 30 “I Am Not Addicted to Valium”
- Case 31 “Of Course, I Worry about Him”
- Case 32 “Bombs Are Falling! Run, Run!”
- Section 5 Substance Abuse Disorders
- Section 6 Personality Disorders
- Case 35 “I Cannot Wait to Get out of This Miserable Place”
- Section 7 Miscellaneous Neuropsychiatric Disorders Affecting Patients in Long-Term Care
- Case 37 “Everyone Is Just So Good to Me!”
- Case 38 “Why Do They Say I Have Dementia?”
- Case 39 “I Hate That Guy … I Can’t Get Any Sleep!”
- Case 40 “Just One Kiss”
- Case 41 “I Don’t Feel Well”
- Case 42 “I Like Food”
- Case 43 “I Like the Way She Laughs”
- Case 44 “This Is So Hard”
- Index
- References
Case 17 - “I Feel Very Lonely”
Depression/Psychogenomic Testing
Published online by Cambridge University Press: 31 October 2024
Book contents
- Clinical Case Studies in Long-Term Care Psychiatry
- Clinical Case Studies in Long-Term Care Psychiatry
- Copyright page
- Contents
- Preface
- Section 1 Neurocognitive Disorders
- Case 2 “I Think I Hit My Head”
- Case 3 “It’s like She’s a Different Person”
- Case 4 “I Am Tired All the Time”
- Case 5 “I Am Okay”
- Case 6 “Leave Me Alone”
- Case 7 “I Am Fine”
- Case 8 “Those Children Are Cute”
- Case 9 “Those Terrible Men Have Left”
- Case 10 “I Saw the Heavenly Gates”
- Case 11 “Leave Me Alone”
- Section 2 Mood Disorders
- Case 13 “My Mom Looks Like a Zombie!”
- Case 14 “My Soul Is in England”
- Case 15 “I Feel Terrible”
- Case 16 “I Don’t Care”
- Case 17 “I Feel Very Lonely”
- Case 18 “I Don’t Feel Right”
- Case 19 “I Am Feeling Great”
- Case 20 “I Am Staying Here Illegally”
- Section 3 Psychotic Disorders
- Case 22 “He Just Won’t Get Up”
- Case 23 “My Body Is Being Taken over by a Fungus!”
- Case 24 “This Is Humiliating”
- Case 25 “I Want to Go Home”
- Case 26 “I Am a Worrier”
- Case 27 “Get out of My House”
- Section 4 Anxiety and Related Disorders
- Case 29 “My Vision Has Been Worsening in the Last Two Weeks”
- Case 30 “I Am Not Addicted to Valium”
- Case 31 “Of Course, I Worry about Him”
- Case 32 “Bombs Are Falling! Run, Run!”
- Section 5 Substance Abuse Disorders
- Section 6 Personality Disorders
- Case 35 “I Cannot Wait to Get out of This Miserable Place”
- Section 7 Miscellaneous Neuropsychiatric Disorders Affecting Patients in Long-Term Care
- Case 37 “Everyone Is Just So Good to Me!”
- Case 38 “Why Do They Say I Have Dementia?”
- Case 39 “I Hate That Guy … I Can’t Get Any Sleep!”
- Case 40 “Just One Kiss”
- Case 41 “I Don’t Feel Well”
- Case 42 “I Like Food”
- Case 43 “I Like the Way She Laughs”
- Case 44 “This Is So Hard”
- Index
- References
Summary
A major influence on positive or negative therapeutic responses to a medication is the drug’s metabolism in a given individual. The metabolism of pharmaceuticals is influenced by age-related factors. Lithium, valproic acid, and carbemazepine levels are still important to obtain periodically when these drugs are used in the management of bipolar disorder and some other psychiatric and neurologic conditions. The metabolism and serum concentrations of medications do not always correlate well with clinical response. At this time pharmacogenetic information used to guide antidepressant therapy does not consistently show improved outcomes. Some studies show improved outcomes and some show no difference in outcomes.
Keywords
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- Chapter
- Information
- Clinical Case Studies in Long-Term Care PsychiatryNavigating Common Mental Health Challenges in Geriatric Care, pp. 83 - 87Publisher: Cambridge University PressPrint publication year: 2024
References
References
Rush, A. J., Trivedi, M. H., Wisniewski, S. R., Nierenberg, A. A., Stewart, J. W., Warden, D., & Fava, M. (2006). Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: A STAR*D report. American Journal of Psychiatry, 163 (11), 1905–1917.CrossRefGoogle ScholarPubMed
Mrazek, D. A., Hornberger, J. C., Altar, C. A., & Degtiar, I. (2014). A review of the clinical, economic, and societal burden of treatment-resistant depression: 1996–2013. Psychiatric services, 65 (8), 977–987.CrossRefGoogle ScholarPubMed
Hampton, L. M., Daubresse, M., Chang, H. Y., Alexander, G. C., & Budnitz, D. S. (2014). Emergency department visits by adults for psychiatric medication adverse events. JAMA Psychiatry, 71 (9), 1006–1014.CrossRefGoogle ScholarPubMed
Genesight. (2021). Pyschotropic Report. https://genesight.com/wp-content/uploads/2021/05/GeneSight.Psychotropic.Report.pdfGoogle Scholar
Further Reading
Bousman, C., Al Maruf, A., & Müller, D. J. (2019). Towards the integration of pharmacogenetics in psychiatry: A minimum, evidence-based genetic testing panel. Current Opinion in Psychiatry, 32 (1), 7–15.CrossRefGoogle ScholarPubMed
Bradley, P., Shiekh, M., Mehra, V., Vrbicky, K., Layle, S., Olson, M. C., & Lukowiak, A. A. (2018). Improved efficacy with targeted pharmacogenetic-guided treatment of patients with depression and anxiety: A randomized clinical trial demonstrating clinical utility. Journal of Psychiatric Research, 96, 100–107.CrossRefGoogle ScholarPubMed
Corponi, F., Fabbri, C., & Serretti, A. (2018). Pharmacogenetics in psychiatry. Advances in Pharmacology, 83, 297–331.CrossRefGoogle ScholarPubMed
Florio, V., Porcelli, S., Saria, A., Serretti, A., & Conca, A. (2017). Escitalopram plasma levels and antidepressant response. European Neuropsychopharmacology, 27 (9), 940–944.CrossRefGoogle ScholarPubMed
Hicks, J. K., Sangkuhl, K., Swen, J. J., Ellingrod, V. L., Müller, D. J., Shimoda, K., & Stingl, J. C. (2017). Clinical pharmacogenetics implementation consortium guideline (CPIC®) for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants: 2016 update. Clinical Pharmacology and Therapeutics, 102 (1), 37.CrossRefGoogle ScholarPubMed
Maciel, A., Cullors, A., Lukowiak, A. A., & Garces, J. (2018). Estimating cost savings of pharmacogenetic testing for depression in real-world clinical settings. Neuropsychiatric Disease and Treatment, 14, 225–230.CrossRefGoogle ScholarPubMed