Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-cd9895bd7-mkpzs Total loading time: 0 Render date: 2024-12-23T06:43:20.108Z Has data issue: false hasContentIssue false

Case 8: From prodrome to psychosis: early-onset schizophrenia

Published online by Cambridge University Press:  09 February 2024

Jeffrey R. Strawn  and
Stephen M. Stahl
Jeffrey R. Strawn
Affiliation:
University of Cincinnati, Ohio
Stephen M. Stahl
Affiliation:
University of California, San Diego
Get access

Summary

Which of the following is U.S. Food and Drug Administration (FDA)-approved for the treatment of schizophrenia in adolescents?

Type
Chapter
Information
Case Studies: Stahl's Essential Psychopharmacology
Children and Adolescents
 , pp. 119 - 136
Publisher: Cambridge University Press
Print publication year: 2023

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Arman, S., Haghshenas, M. Metabolic effects of adding topiramate on aripiprazole in bipolar patients aged between 6–18 years: a randomized, double-blind, placebo-controlled trial. J Res Med Sci 2022; 27(1): 23. https://doi.org/10.4103/jrms.jrms_672_21Google Scholar
Bosnjak Kuharic, D., Kekin, I., Hew, J., Rojnic Kuzman, M., Puljak, L. Interventions for prodromal stage of psychosis. Cochrane Database Syst Rev 2019; 2019(11): CD012236. https://doi.org/10.1002/14651858.CD012236.pub2Google Scholar
DelBello, M. P., Strawn, J. R., Duran, L. P. 1.6 Recognition and management of second-generation antipsychotic-associated adverse effects. J Am Acad Child Adolesc Psychiatry 2017; 56(10): S135. https://doi.org/10.1016/j.jaac.2017.07.509Google Scholar
Freeman, M. P., McInerney, K., Sosinsky, A. Z., Kwiatkowski, M. A., Cohen, L. S. Omega-3 fatty acids for atypical antipsychotic-associated hypertriglyceridemia. Ann Clin Psychiatry 2015; 27(3): 197–202. https://doi.org/10.1016/j.jaac.2016.12.013Google Scholar
McClellan, J., Stock, S.; American Academy of Child and Adolescent Psychiatry (AACAP) Committee on Quality Issues (CQI). Practice parameter for the assessment and treatment of children and adolescents with schizophrenia. J Am Acad Child Adolesc Psychiatry 2013; 52(9): 976–90. https://doi.org/10.1016/j.jaac.2013.02.008Google Scholar
Pagsberg, A. K., Tarp, S., Glintborg, D., et al. Acute antipsychotic treatment of children and adolescents with schizophrenia-spectrum disorders: a systematic review and network meta-analysis. J Am Acad Child Adolesc Psychiatry 2017; 56(3): 191–202. https://doi.org/10.1016/j.jaac.2016.12.013Google Scholar
Savitz, A., Lane, R., Nuamah, I., et al. Long-term safety of paliperidone extended release in adolescents with schizophrenia: an open-label, flexible dose study. J Child Adolesc Psychopharmacol 2015; 25(7): 548–57. https://doi.org/10.1089/cap.2014.0130Google Scholar
Singh, J., Robb, A., Vijapurkar, U., Nuamah, I., Hough, D. A randomized, double-blind study of paliperidone extended-release in treatment of acute schizophrenia in adolescents. Biological Psychiatry 2011; 70(12): 1179–87. https://doi.org/10.1016/j.biopsych.2011.06.021Google Scholar
Siskind, D., Hahn, M., Correll, C. U., et al. Glucagon-like peptide-1 receptor agonists for antipsychotic-associated cardio-metabolic risk factors: a systematic review and individual participant data meta-analysis. Diabetes Obes Metab 2019; 21(2): 293–302. https://doi.org/10.1111/dom.13522Google Scholar
Siskind, D. J., Russell, A. W., Gamble, C., et al. Treatment of clozapine-associated obesity and diabetes with exenatide in adults with schizophrenia: a randomized controlled trial (CODEX). Diabetes Obes Metab 2018; 20(4): 1050–55. https://doi.org/10.1111/dom.13167Google Scholar
Strawn, J. R., DelBello, M. P. 59.4 Recognizing and managing side effects of second-generation antipsychotics. J Am Acad Child Adolesc Psychiatry 2018; 57(10): S85. https://doi.org/10.1016/j.jaac.2018.07.358Google Scholar
Sunshine, A., McClellan, J. Practitioner Review: psychosis in children and adolescents. J Child Psychol Psychiatry. 2023. doi: 10.1111/jcpp.13777. Epub ahead of print. PMID: 36878476.Google Scholar
Xu, X., Shao, G., Zhang, X., et al. The efficacy of nutritional supplements for the adjunctive treatment of schizophrenia in adults: a systematic review and network meta-analysis. Psychiatry Res 2022; 311: 114500. https://doi.org/10.1016/j.psychres.2022.114500Google Scholar

Save book to Kindle

To save this book to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×