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Case 16: Second-generation antipsychotics/mixed dopamine–serotonin receptor agonists (SGAs), side effects, and the autism spectrum: SGA-related side effects in a boy with autism spectrum disorder (ASD)

Published online by Cambridge University Press:  09 February 2024

Jeffrey R. Strawn
Affiliation:
University of Cincinnati, Ohio
Stephen M. Stahl
Affiliation:
University of California, San Diego
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Summary

Which of the following is associated with the greatest incidence of hyperprolactinemia?

Type
Chapter
Information
Case Studies: Stahl's Essential Psychopharmacology
Children and Adolescents
, pp. 259 - 278
Publisher: Cambridge University Press
Print publication year: 2023

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References

Aman, M., Rettiganti, M., Nagaraja, H. N., et al. Tolerability, safety, and benefits of risperidone in children and adolescents with autism: 21-month follow-up after 8-week placebo-controlled trial. J Child Adolesc Psychopharmacol 2015; 25(6): 482–93. https://doi.org/10.1089/cap.2015.0005Google Scholar
Dominick, K. C., Wink, L. K., Pedapati, E. V., et al. Risperidone treatment for irritability in fragile X syndrome. J Child Adolesc Psychopharmacol 2018, 28(4): 274–78. https://doi.org/10.1089/cap.2017.0057Google Scholar
Erickson, C. A., Stigler, K. A., Wink, L. K., et al. A prospective open-label study of aripiprazole in fragile X syndrome. Psychopharmacology 2011; 216(1): 8590. https://doi.org/10.1007/s00213-011-2194-7Google Scholar
Gotham, K., Pickles, A., Lord, C. Standardizing ADOS scores for a measure of severity in autism spectrum disorders. J Autism Develop Disord 2009; 39(5): 693705. https://doi.org/10.1007/s10803-008-0674-3Google Scholar
Gotham, K., Risi, S., Pickles, A., Lord, C. The autism diagnostic observation schedule: revised algorithms for improved diagnostic validity. J Autism Develop Disord 2007; 37(4): 613–27. https://doi.org/10.1007/s10803-006-0280-1Google Scholar
Hersh, J. H., Saul, R. A. Health supervision for children with fragile X syndrome (clinical report). In Pediatric Clinical Practice Guidelines & Policies. Itasca, IL: American Academy of Pediatrics, 2021. https://doi.org/10.1542/9781581108224-health8_sub01Google Scholar
Kloosterboer, S. M., de Winter, B. C. M., Reichart, C. G., et al. Risperidone plasma concentrations are associated with side effects and effectiveness in children and adolescents with autism spectrum disorder. Br J Clin Pharmacol 2021; 87(3): 1069–81. https://doi.org/10.1111/bcp.14465Google Scholar
Koch, M. T., Carlson, H. E., Kazimi, M. M., Correll, C. U. Antipsychotic-related prolactin levels and sexual dysfunction in mentally ill youth: a 3-month cohort study. J Am Acad Child Adolesc Psychiatry 2023; 15: S08908567(23)00125-9. doi: 10.1016/j.jaac.2023.03.007. Epub ahead of print. PMID: 36931560.Google Scholar
McCracken, J. T., McGough, J., Shah, B., et al. Risperidone in children with autism and serious behavioral problems. N Engl J Med 2002; 347(5): 314–21. https://doi.org/10.1056/nejmoa013171Google Scholar
Muhle, R. A., Reed, H. E., Vo, L. C., et al. Clinical diagnostic genetic testing for individuals with developmental disorders. J Am Acad Child Adolesc Psychiatry 2017; 56(11): 910–13. https://doi.org/10.1016/j.jaac.2017.09.418Google Scholar
Savatt, J. M., Myers, S. M. Genetic testing in neurodevelopmental disorders. Front Pediatr 2021; 9. https://doi.org/10.3389/fped.2021.526779Google Scholar
Strawn, J. R., Geracioti, T. D. Editorial: a better perspective on antipsychotic-related hyperprolactinemia in children and adolescents. J Am Acad Child Adolesc Psychiatry 2023: S0890-8567(23)00240-X. doi: 10.1016/j.jaac.2023.05.003. Epub ahead of print. PMID: 37172820.Google Scholar

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