Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-586b7cd67f-2plfb Total loading time: 0 Render date: 2024-11-26T09:05:49.592Z Has data issue: false hasContentIssue false

Chapter 12 - Malignant Hyperthermia

Published online by Cambridge University Press:  30 November 2019

By
Giselle Torres
Edited by
Adam C. Adler ,
Arvind Chandrakantan  and
Ronald S. Litman
Adam C. Adler
Affiliation:
Texas Children's Hospital
Arvind Chandrakantan
Affiliation:
Texas Children's Hospital
Ronald S. Litman
Affiliation:
The Children's Hospital of Philadelphia
Get access

Summary

This chapter provides a review of malignant hyperthermia. The author discusses the considerations related to intraoperative hyperthermia. The differential diagnosis of severe perioperative hyperthermia is considered including thyroid storm and neuroleptic malignant syndrome. The incidence, genetics, diagnostic testing and treatment of malignant hyperthermia is presented.

Keywords

Malignant Hyperthermiamuscle rigiditymasseter muscle spasmmetabolic acidosisneuroleptic malignant syndromethyroid storm.
Type
Chapter
Information
Case Studies in Pediatric Anesthesia , pp. 57 - 59
Publisher: Cambridge University Press
Print publication year: 2019

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Suggested Reading

Birgenheier, N, Stoker, R, Westenskow, D, et al. Activated charcoal effectively removes inhaled anesthetics from modern anesthesia machines. Anesth Analg. 2011;112(6):1363–70. PMID: 21543783.CrossRefGoogle ScholarPubMed
Kim, TW, Nemergut, ME. Preparation of modern anesthesia workstations for malignant hyperthermia-susceptible patients: a review of past and present practice. Anesthesiology. 2011;114(1):205–12. PMID: 21169802.CrossRefGoogle ScholarPubMed
Larach, MG, Gronert, GA, Allen, GC, et al. Clinical presentation, treatment, and complications of malignant hyperthermia in North America from 1987 to 2006. Anesth Analg. 2010 Feb 1;110(2):498–507. PMID: 20081135.CrossRefGoogle ScholarPubMed
Nelson, P, Litman, RS. Malignant hyperthermia in children: an analysis of the North American malignant hyperthermia registry. Anesth Analg. 2014;118(2):369–74. PMID: 24299931.CrossRefGoogle ScholarPubMed
Rosero, EB, Adesanya, AO, Timaran, CH, et al. Trends and outcomes of malignant hyperthermia in the United States, 2000 to 2005. Anesthesiology. 2009;110(1):89–94. PMID: 19104175.CrossRefGoogle ScholarPubMed
Salazar, JH, Yang, J, Shen, L, et al. Pediatric malignant hyperthermia: risk factors, morbidity, and mortality identified from the Nationwide Inpatient Sample and Kids’ Inpatient Database. Paediatr Anaesth. 2014;24(12):1212–6. PMID: 24974921.CrossRefGoogle ScholarPubMed
Wappler, F. Anesthesia for patients with a history of malignant hyperthermia. Curr Opin Anaesthesiol. 2010;23(3):417–22. PMID: 20173632.CrossRefGoogle ScholarPubMed

Save book to Kindle

To save this book to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×