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23 - PaCO2, PetCO2, and gradient

from 1 - Ventilation

Published online by Cambridge University Press:  05 August 2011

J. S. Gravenstein
Affiliation:
University of Florida
Michael B. Jaffe
Affiliation:
Philip Healthcare
Nikolaus Gravenstein
Affiliation:
University of Florida
David A. Paulus
Affiliation:
University of Florida
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Summary

Quantitative and/or qualitative analysis of exhaled carbon dioxide (CO2) has become standard practice in many clinical situations. The rationale for measuring the partial pressure of CO2 (PCO2) in exhaled gas is the assumption that end-tidal PCO2 (PETCO2) is a reflection of alveolar PCO2 (PaCO2). Hemoglobin plays an essential role in CO2 transport and elimination. Elimination of CO2 from the lung occurs as a function of gas exchange between the atmosphere and alveoli. In order to gain a greater understanding of the gradient between PaCO2 and PETCO2, an analysis of the interaction of pulmonary ventilation and perfusion is necessary. The alveolar gas equation (AGE) is used to analyze the effect of ventilation on oxygenation of arterial blood. An understanding of the interrelationship between pulmonary perfusion, ventilation, tidal volume, and regional VA/Q will enhance the utility of capnography as a monitor.
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Capnography , pp. 225 - 230
Publisher: Cambridge University Press
Print publication year: 2011

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