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9.8 - Bipolar Affective Disorder

from 9 - Integrated Neurobiology of Specific Syndromes and Treatments

Published online by Cambridge University Press:  08 November 2023

By
Nefize Yalin  and
Allan H. Young
Edited by
Mary-Ellen Lynall ,
Peter B. Jones  and
Stephen M. Stahl
Mary-Ellen Lynall
Affiliation:
University of Cambridge
Peter B. Jones
Affiliation:
University of Cambridge
Stephen M. Stahl
Affiliation:
University of California, San Diego
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Summary

Bipolar affective disorder is characterised by episodes of (hypo)mania and depression, and well-being states called euthymia [1]. The neurobiology of bipolar affective disorder is highly complex with several biological pathways putatively involved [1]. Despite the large amount of research on the pathophysiology of bipolar affective disorder, diagnosis still depends solely on symptomatology and validated biological markers for diagnostic accuracy and treatment decisions remain to be determined [1]. This section summarises present findings on the biological mechanisms of bipolar affective disorder and highlights future research priorities.

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Chapter
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Cambridge Textbook of Neuroscience for Psychiatrists , pp. 449 - 455
Publisher: Cambridge University Press
Print publication year: 2023

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References

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