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9.8 - Bipolar Affective Disorder

from 9 - Integrated Neurobiology of Specific Syndromes and Treatments

Published online by Cambridge University Press:  08 November 2023

Mary-Ellen Lynall
Affiliation:
University of Cambridge
Peter B. Jones
Affiliation:
University of Cambridge
Stephen M. Stahl
Affiliation:
University of California, San Diego
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Summary

Bipolar affective disorder is characterised by episodes of (hypo)mania and depression, and well-being states called euthymia [1]. The neurobiology of bipolar affective disorder is highly complex with several biological pathways putatively involved [1]. Despite the large amount of research on the pathophysiology of bipolar affective disorder, diagnosis still depends solely on symptomatology and validated biological markers for diagnostic accuracy and treatment decisions remain to be determined [1]. This section summarises present findings on the biological mechanisms of bipolar affective disorder and highlights future research priorities.

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Chapter
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Publisher: Cambridge University Press
Print publication year: 2023

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References

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