Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-586b7cd67f-gb8f7 Total loading time: 0 Render date: 2024-11-27T00:06:15.522Z Has data issue: false hasContentIssue false

32 - Anhedonia in Addictive Behaviors

from Part V - Ongoing and Future Research Directions

Published online by Cambridge University Press:  13 July 2020

By
Walter G. Dyer ,
Adam M. Leventhal ,
Nicholas I. Goldenson  and
Mariel S. Bello
Edited by
Steve Sussman
Steve Sussman
Affiliation:
University of Southern California
Get access

Summary

Anhedonia – a diminished interest in, or ability to experience pleasure from, common rewarding stimuli – is implicated in addictive behaviors. Integrative reviews of extant research on the role of anhedonia in understanding addictive behaviors are dated and overlook nonsubstance addictions. This chapter reviews the anhedonia construct, describes theoretical models of mechanisms linking anhedonia to addiction, summarizes and synthesizes the empirical evidence on anhedonia in addictive behaviors in humans, and proposes future research directions. From the literature review and integration, it is concluded that: (1) anhedonia may be a risk factor and consequence of addictive behaviors, (2) anhedonia may increase motivation to engage in addictive behaviors to offset deficient pleasure, and (3) anhedonia is generally correlated with onset, escalation, persistence, and relapse to a variety of addictive behaviors in prior research. Addictive agents, intervention applications, and other topics overlooked in the study of anhedonia in addictive behaviors warrant further inquiry to advance addiction science and practice.

Keywords

anhedoniatraitstateanticipatoryconsummatoryreward allostasisemotional vulnerabilitydrugsfoodinternetextreme sportspharmacotherapymindfulnesspositive psychotherapy
Type
Chapter
Information
The Cambridge Handbook of Substance and Behavioral Addictions , pp. 386 - 408
Publisher: Cambridge University Press
Print publication year: 2020

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Albertella, L., Le Pelley, M. E., Yücel, M. & Copeland, J. (2018). Age moderates the association between frequent cannabis use and negative schizotypy over time. Addictive Behaviors, 87, 183–189.Google Scholar
Bersani, G., Orlandi, V., Gherardelli, S. & Pancheri, P. (2002). Cannabis and neurological soft signs in schizophrenia: absence of relationship and influence on psychopathology. Psychopathology, 35(5), 289–295.Google Scholar
Bickel, W. K., Jarmolowicz, D. P., Mueller, E. T. & Gatchalian, K. M. (2011). The behavioral economics and neuroeconomics of reinforcer pathologies: implications for etiology and treatment of addiction. Current Psychiatry Reports, 13(5), 406.CrossRefGoogle ScholarPubMed
Bovasso, G. B. (2001). Cannabis abuse as a risk factor for depressive symptoms. American Journal of Psychiatry, 158(12), 2033–2037.Google Scholar
Brikmanis, K., Petersen, A. & Doran, N. (2017). Do personality traits related to affect regulation predict other tobacco product use among young adult non-daily smokers? Addictive Behaviors, 75, 79–84.CrossRefGoogle ScholarPubMed
Bruijnzeel, A. W. & Markou, A. (2003). Characterization of the effects of bupropion on the reinforcing properties of nicotine and food in rats. Synapse, 50(1), 20–28.Google Scholar
Cano, M. Á., de Dios, M. A., Correa-Fernández, V., et al. (2017). Depressive symptom domains and alcohol use severity among Hispanic emerging adults: examining moderating effects of gender. Addictive Behaviors, 72, 72–78.Google Scholar
Carleton, R. N., Thibodeau, M. A., Teale, M. J., et al. (2013). The center for epidemiologic studies depression scale: a review with a theoretical and empirical examination of item content and factor structure. PLoS ONE, 8(3), e58067.Google Scholar
Carroll, K. M., Nich, C., Frankforter, T. L., et al. (2018). Accounting for the uncounted: physical and affective distress in individuals dropping out of oral naltrexone treatment for opioid use disorder. Drug and Alcohol Dependence, 192, 264–270.Google Scholar
Carton, L., Pignon, B., Baguet, A., et al. (2018). Influence of comorbid alcohol use disorders on the clinical patterns of major depressive disorder: a general population-based study. Drug and Alcohol Dependence, 187, 40–47.CrossRefGoogle ScholarPubMed
Chuang, C. W. I., Chan, C. & Leventhal, A. M. (2016). Adolescent emotional pathology and lifetime history of alcohol or drug use with and without comorbid tobacco use. Journal of Dual Diagnosis, 12(1), 27–35.Google Scholar
Cho, J., Stone, M. D. & Leventhal, A. M. (2019). Anhedonia as a phenotypic marker of familial transmission of polysubstance use trajectories across midadolescence. Psychology of Addictive Behaviors, 33(1), 15–25.CrossRefGoogle ScholarPubMed
Cobb, N. K., Byron, M. J., Abrams, D. B. & Shields, P. G. (2010). Novel nicotine delivery systems and public health: the rise of the “e-cigarette”. American Journal of Public Health, 100(12), 2340–2342.Google Scholar
Cohen, A. S., Najolia, G. M., Brown, L. A. & Minor, K. S. (2011). The state-trait disjunction of anhedonia in schizophrenia: potential affective, cognitive and social-based mechanisms. Clinical Psychology Review, 31(3), 440–448.CrossRefGoogle ScholarPubMed
Cook, J. W., Lanza, S. T., Chu, W., Baker, T. B. & Piper, M. E. (2017). Anhedonia: its dynamic relations with craving, negative affect, and treatment during a quit smoking attempt. Nicotine & Tobacco Research, 19(6), 703–709.Google Scholar
Cook, J. W., Piper, M. E., Leventhal, A. M., et al. (2015). Anhedonia as a component of the tobacco withdrawal syndrome. Journal of Abnormal Psychology, 124(1), 215.Google Scholar
Creamer, M. R., Perry, C. L., Harrell, M. B. & Diamond, P. M. (2015). Trends in multiple tobacco product use among high school students. Tobacco Regulatory Science, 1(3), 204–214.CrossRefGoogle ScholarPubMed
Crits-Christoph, P., Wadden, S., Gaines, A., et al. (2018). Symptoms of anhedonia, not depression, predict the outcome of treatment of cocaine dependence. Journal of Substance Abuse Treatment, 92, 46–50.Google Scholar
Cryan, J. F., Dalvi, A., Jin, , et al. (2001). Use of dopamine-β-hydroxylase-deficient mice to determine the role of norepinephrine in the mechanism of action of antidepressant drugs. Journal of Pharmacology and Experimental Therapeutics, 298(2), 651–657.Google Scholar
Cryan, J. F., O'Leary, O. F., Jin, S. H., et al. (2004). Norepinephrine-deficient mice lack responses to antidepressant drugs, including selective serotonin reuptake inhibitors. Proceedings of the National Academy of Sciences, 101(21), 8186–8191.Google Scholar
Curtin, S. C., Tejada-Vera, B. & Warmer, M. (2017). Drug overdose deaths among adolescents aged 15–19 in the United States: 1999-2015. NCHS Data Brief, 282, 1–8.Google Scholar
Daughters, S. B., Magidson, J. F., Anand, D., et al. (2018). The effect of a behavioral activation treatment for substance use on post‐treatment abstinence: a randomized controlled trial. Addiction, 113(3), 535–544.CrossRefGoogle ScholarPubMed
D’Souza, M. S. & Markou, A. (2010). Neural substrates of psychostimulant withdrawal-induced anhedonia. In Behavioral Neuroscience of Drug Addiction. Berlin, Heidelberg: Springer, pp. 119–178.Google Scholar
Davis, C. & Woodside, D. B. (2002). Sensitivity to the rewarding effects of food and exercise in the eating disorders. Comprehensive Psychiatry, 43(3), 189–194.Google Scholar
Deng, Y., Chang, L., Yang, M., Huo, M. & Zhou, R. (2016). Gender differences in emotional response: inconsistency between experience and expressivity. PLoS ONE, 11(6), e0158666.Google Scholar
Dervaux, A., Laqueille, X., Bourdel, M. C., Olié, J. P. & Krebs, M. O. (2010). Impulsivity and sensation seeking in alcohol abusing patients with schizophrenia. Frontiers in Psychiatry, 1, 135.Google Scholar
Dorard, G., Berthoz, S., Phan, O., Corcos, M. & Bungener, C. (2008). Affect dysregulation in cannabis abusers. European Child & Adolescent Psychiatry, 17(5), 274–282.Google Scholar
Dumas, P., Saoud, M., Bouafia, S., et al. (2002). Cannabis use correlates with schizotypal personality traits in healthy students. Psychiatry Research, 109(1), 27–35.Google Scholar
Dutra, L., Stathopoulou, G., Basden, S. L., et al. (2008). A meta-analytic review of psychosocial interventions for substance use disorders. American Journal of Psychiatry, 165(2), 179–187.Google Scholar
Eiber, R., Berlin, I., de Brettes, B., Foulon, C. & Guelfi, J. D. (2002). Hedonic response to sucrose solutions and the fear of weight gain in patients with eating disorders. Psychiatry Research, 113(1–2), 173–180.Google Scholar
Erwin, M. C., Charak, R., Durham, T. A., et al. (2017). The 7-factor hybrid model of DSM-5 PTSD symptoms and alcohol consumption and consequences in a national sample of trauma-exposed veterans. Journal of Anxiety Disorders, 51, 14–21.Google Scholar
Fawcett, J., Clark, D. C., Scheftner, W. A. & Gibbons, R. D. (1983). Assessing anhedonia in psychiatric patients: the pleasure scale. Archives of General Psychiatry, 40(1), 79–84.Google Scholar
Feingold, D., Rehm, J. & Lev-Ran, S. (2017). Cannabis use and the course and outcome of major depressive disorder: a population based longitudinal study. Psychiatry Research, 251, 225–234.Google Scholar
Fiore, M. C., Jaen, C. R., Baker, T. B., et al. (2008). Treating Tobacco Use and Dependence: 2008 Update. Rockville, MD: US Department of Health and Human Services.Google Scholar
Fiorito, E. R. & Simons, R. F. (1994). Emotional imagery and physical anhedonia. Psychophysiology, 31(5), 513–521.Google Scholar
Franken, I. H., Zijlstra, C. & Muris, P. (2006). Are nonpharmacological induced rewards related to anhedonia? A study among skydivers. Progress in Neuro-psychopharmacology and Biological Psychiatry, 30(2), 297–300.CrossRefGoogle ScholarPubMed
Gard, D. E., Gard, M. G., Kring, A. M. & John, O. P. (2006). Anticipatory and consummatory components of the experience of pleasure: a scale development study. Journal of Research in Personality, 40(6), 1086–1102.Google Scholar
Garfield, J. B., Cotton, S. M., Allen, N. B., et al. (2017). Evidence that anhedonia is a symptom of opioid dependence associated with recent use. Drug and Alcohol Dependence, 177, 29–38.Google Scholar
Garfield, J. B., Lubman, D. I. & Yücel, M. (2014). Anhedonia in substance use disorders: a systematic review of its nature, course and clinical correlates. Australian & New Zealand Journal of Psychiatry, 48(1), 36–51.Google Scholar
Garland, E. L., Froeliger, B. & Howard, M. O. (2014). Effects of Mindfulness-Oriented Recovery Enhancement on reward responsiveness and opioid cue-reactivity. Psychopharmacology, 231(16), 3229–3238.Google Scholar
Garland, E. L., Froeliger, B. & Howard, M. O. (2015). Neurophysiological evidence for remediation of reward processing deficits in chronic pain and opioid misuse following treatment with Mindfulness-Oriented Recovery Enhancement: exploratory ERP findings from a pilot RCT. Journal of Behavioral Medicine, 38(2), 327–336.Google Scholar
Geschwind, N., Peeters, F., Drukker, M., van Os, J. & Wichers, M. (2011). Mindfulness training increases momentary positive emotions and reward experience in adults vulnerable to depression: a randomized controlled trial. Journal of Consulting and Clinical Psychology, 79(5), 618.Google Scholar
Guillot, C. R., Halliday, T. M., Kirkpatrick, M. G., Pang, R. D. & Leventhal, A. M. (2017). Anhedonia and abstinence as predictors of the subjective pleasantness of positive, negative, and smoking-related pictures. Nicotine & Tobacco Research, 19(6), 743–749.Google Scholar
Hall, W. & Lynskey, M. (2016). Evaluating the public health impacts of legalizing recreational cannabis use in the United States. Addiction, 111(10), 1764–1773.CrossRefGoogle ScholarPubMed
Harvey, P. O., Pruessner, J., Czechowska, Y. & Lepage, M. (2007). Individual differences in trait anhedonia: a structural and functional magnetic resonance imaging study in non-clinical subjects. Molecular Psychiatry, 12(8), 767.Google Scholar
Haslam, A. K., Correa-Fernández, V., Hoover, D. S., et al. (2018). Anhedonia and smoking cessation among Spanish-speaking Mexican-Americans. Health Psychology, 37(9), 814.Google Scholar
Hatzigiakoumis, D. S., Martinotti, G., Di Giannantonio, M. & Janiri, L. (2011). Anhedonia and substance dependence: clinical correlates and treatment options. Frontiers in Psychiatry, 2, 10.CrossRefGoogle ScholarPubMed
Heirene, R. M., Shearer, D., Roderique-Davies, G. & Mellalieu, S. D. (2016). Addiction in extreme sports: an exploration of withdrawal states in rock climbers. Journal of Behavioral Addictions, 5(2), 332–341.CrossRefGoogle ScholarPubMed
Higgins, S. T., Silverman, K. & Heil, S. H. (Eds.) (2007). Contingency Management in Substance Abuse Treatment. Guilford Press.Google Scholar
Hughes, J. R., Budney, A. J., Muellers, S. R., et al. (2017). Does tobacco abstinence decrease reward sensitivity? A human laboratory test. Nicotine & Tobacco Research, 19(6), 677–685.Google Scholar
Huhn, A. S., Meyer, R. E., Harris, J. D., et al. (2016). Evidence of anhedonia and differential reward processing in prefrontal cortex among post-withdrawal patients with prescription opiate dependence. Brain Research Bulletin, 123, 102–109.CrossRefGoogle ScholarPubMed
Huys, Q. J., Pizzagalli, D. A., Bogdan, R. & Dayan, P. (2013). Mapping anhedonia onto reinforcement learning: a behavioural meta-analysis. Biology of Mood & Anxiety Disorders, 3(1), 12.CrossRefGoogle ScholarPubMed
Janiri, L., Martinotti, G., Dario, T., et al. (2005). Anhedonia and substance-related symptoms in detoxified substance-dependent subjects: a correlation study. Neuropsychobiology, 52(1), 37–44.CrossRefGoogle ScholarPubMed
Johnson, K. A., Bonn-Miller, M. O., Leyro, T. M. & Zvolensky, M. J. (2009). Anxious arousal and anhedonic depression symptoms and the frequency of current marijuana use: testing the mediating role of marijuana-use coping motives among active users. Journal of Studies on Alcohol and Drugs, 70(4), 543–550.Google Scholar
Kahler, C. W., Spillane, N. S., Day, A., et al. (2014). Positive psychotherapy for smoking cessation: treatment development, feasibility, and preliminary results. The Journal of Positive Psychology, 9(1), 19–29.Google Scholar
Kahler, C. W., Spillane, N. S., Day, A. M., et al. (2015). Positive psychotherapy for smoking cessation: a pilot randomized controlled trial. Nicotine & Tobacco Research, 17(11), 1385–1392.Google Scholar
Kelley, A. E. & Berridge, K. C. (2002). The neuroscience of natural rewards: relevance to addictive drugs. Journal of Neuroscience, 22(9), 3306–3311.Google Scholar
Kirkpatrick, M. G., Goldenson, N. I., Kapadia, N., et al. (2016). Emotional traits predict individual differences in amphetamine-induced positive mood in healthy volunteers. Psychopharmacology, 233(1), 89–97.Google Scholar
Koob, G. F. & Le Moal, M. (2001). Drug addiction, dysregulation of reward, and allostasis. Neuropsychopharmacology, 24(2), 97.Google Scholar
Krupitsky, E. M., Burakov, A. M., Didenko, T. Y., et al. (2002). Effects of citalopram treatment of protracted withdrawal (syndrome of anhedonia) in patients with heroin addiction. Addictive Disorders & Their Treatment, 1(1), 29–33.Google Scholar
Krupitsky, E., Zvartau, E., Blokhina, E., et al. (2016). Anhedonia, depression, anxiety, and craving in opiate dependent patients stabilized on oral naltrexone or an extended release naltrexone implant. The American Journal of Drug and Alcohol Abuse, 42(5), 614–620.Google Scholar
Lawn, W., Freeman, T. P., Pope, R. A., et al. (2016). Acute and chronic effects of cannabinoids on effort-related decision-making and reward learning: an evaluation of the cannabis ‘amotivational’ hypotheses. Psychopharmacology, 233(19–20), 3537–3552.Google Scholar
Lee, Y. O., Hebert, C. J., Nonnemaker, J. M. & Kim, A. E. (2015). Youth tobacco product use in the United States. Pediatrics, 135(3), 409–415.Google Scholar
Leibenluft, E., Fiero, P. L., Bartko, J. J., Moul, D. E. & Rosenthal, N. E. (1993). Depressive symptoms and the self-reported use of alcohol, caffeine, and carbohydrates in normal volunteers and four groups of psychiatric outpatients. American Journal of Psychiatry, 150, 294–294.Google Scholar
Lejuez, C. W., Hopko, D. R. & Hopko, S. D. (2001). A brief behavioral activation treatment for depression: treatment manual. Behavior Modification, 25(2), 255–286.Google Scholar
Leventhal, A. M. & Zvolensky, M. J. (2015). Anxiety, depression, and cigarette smoking: a transdiagnostic vulnerability framework to understanding emotion–smoking comorbidity. Psychological Bulletin, 141(1), 176.Google Scholar
Leventhal, A. M., Brightman, M., Ameringer, K. J., et al. (2010). Anhedonia associated with stimulant use and dependence in a population-based sample of American adults. Experimental and Clinical Psychopharmacology, 18(6), 562.Google Scholar
Leventhal, A. M., Chasson, G. S., Tapia, E., Miller, E. K. & Pettit, J. W. (2006). Measuring hedonic capacity in depression: a psychometric analysis of three anhedonia scales. Journal of Clinical Psychology, 62(12), 1545–1558.Google Scholar
Leventhal, A. M., Cho, J., Stone, M. D., et al. (2017). Associations between anhedonia and marijuana use escalation across mid‐adolescence. Addiction, 112(12), 2182–2190.Google Scholar
Leventhal, A. M., Piper, M. E., Japuntich, S. J., Baker, T. B. & Cook, J. W. (2014). Anhedonia, depressed mood, and smoking cessation outcome. Journal of Consulting and Clinical Psychology, 82(1), 122.Google Scholar
Leventhal, A. M., Ramsey, S. E., Brown, R. A., LaChance, H. R. & Kahler, C. W. (2008). Dimensions of depressive symptoms and smoking cessation. Nicotine & Tobacco Research, 10(3), 507–517.Google Scholar
Leventhal, A. M., Strong, D. R., Sussman, S., et al. (2016). Psychiatric comorbidity in adolescent electronic and conventional cigarette use. Journal of Psychiatric Research, 73, 71–78.Google Scholar
Lichlyter, B., Purdon, S. & Tibbo, P. (2011). Predictors of psychosis severity in individuals with primary stimulant addictions. Addictive Behaviors, 36(1–2), 137–139.Google Scholar
Liverant, G. I., Sloan, D. M., Pizzagalli, D. A., et al. (2014). Associations among smoking, anhedonia, and reward learning in depression. Behavior Therapy, 45(5), 651–663.Google Scholar
Liu, C. H. & Tronick, E. (2014). Prevalence and predictors of maternal postpartum depressed mood and anhedonia by race and ethnicity. Epidemiology and Psychiatric Sciences, 23(2), 201–209.Google Scholar
Lubman, D. I., Garfield, J. B., Gwini, S. M., et al. (2018). Dynamic associations between opioid use and anhedonia: a longitudinal study in opioid dependence. Journal of Psychopharmacology, 32(9), 957–964.CrossRefGoogle ScholarPubMed
Luby, J. L., Agrawal, A., Belden, A., et al. (2018). Developmental trajectories of the orbitofrontal cortex and anhedonia in middle childhood and risk for substance use in adolescence in a longitudinal sample of depressed and healthy preschoolers. American Journal of Psychiatry, 175(10), 1010–1021.Google Scholar
MacPherson, L., Tull, M. T., Matusiewicz, A. K., et al. (2010). Randomized controlled trial of behavioral activation smoking cessation treatment for smokers with elevated depressive symptoms. Journal of Consulting and Clinical Psychology, 78(1), 55.CrossRefGoogle ScholarPubMed
Marra, D., Warot, D., Payan, C., et al. (1998). Anhedonia and relapse in alcoholism. Psychiatry Research, 80(2), 187–196.Google Scholar
Martinotti, G., Cloninger, C. R. & Janiri, L. (2008a). Temperament and character inventory dimensions and anhedonia in detoxified substance-dependent subjects. American Journal of Drug and Alcohol Abuse, 34(2), 177–183. doi:10.1080/00952990701877078Google Scholar
Martinotti, G., Di Nicola, M., Reina, D., et al. (2008b). Alcohol protracted withdrawal syndrome: the role of anhedonia. Substance Use & Misuse, 43(3–4), 271–284.Google Scholar
Martinotti, G., Andreoli, S., Reina, D., et al. (2011). Acetyl-l-carnitine in the treatment of anhedonia, melancholic and negative symptoms in alcohol dependent subjects. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 35(4), 953–958.Google Scholar
Mathew, A. R., Cook, J. W., Japuntich, S. J. & Leventhal, A. M. (2015). Post‐traumatic stress disorder symptoms, underlying affective vulnerabilities, and smoking for affect regulation. The American Journal on Addictions, 24(1), 39–46.Google Scholar
McClure, E. A., Vandrey, R. G., Johnson, M. W. & Stitzer, M. L. (2012). Effects of varenicline on abstinence and smoking reward following a programmed lapse. Nicotine & Tobacco Research, 15(1), 139–148.Google Scholar
McGregor, C., Srisurapanont, M., Jittiwutikarn, J., et al. (2005). The nature, time course and severity of methamphetamine withdrawal. Addiction, 100(9), 1320–1329.Google Scholar
Meehl, P. E. (1975). Hedonic capacity: some conjectures. Bulletin of the Menninger Clinic, 39(4), 295–307.Google ScholarPubMed
Meshesha, L. Z., Pickover, A. M., Teeters, J. B. & Murphy, J. G. (2017). A longitudinal behavioral economic analysis of non-medical prescription opioid use among college students. The Psychological Record, 67(2), 241–251.Google Scholar
Miotto, P., Preti, A. & Frezza, M. (2001). Heroin and schizophrenia: subjective responses to abused drugs in dually diagnosed patients. Journal of Clinical Psychopharmacology, 21(1), 111–113.Google Scholar
Morie, K. P., De Sanctis, P., Garavan, H. & Foxe, J. J. (2014). Executive dysfunction and reward dysregulation: a high-density electrical mapping study in cocaine abusers. Neuropharmacology, 85, 397–407.CrossRefGoogle ScholarPubMed
Newton, T. F., Kalechstein, A. D., Duran, S., Vansluis, N. & Ling, W. (2004). Methamphetamine abstinence syndrome: preliminary findings. The American Journal on Addictions, 13(3), 248–255.Google Scholar
Noordsy, D. L., Drake, R. E., Teague, G. B., et al. (1991). Subjective experiences related to alcohol use among schizophrenics. Journal of Nervous and Mental Disease, 179(7), 410–414.Google Scholar
Nunn, J. A., Rizza, F. & Peters, E. R. (2001). The incidence of schizotypy among cannabis and alcohol users. The Journal of Nervous and Mental Disease, 189(11), 741–748.Google Scholar
Pang, R. D., Khoddam, R., Guillot, C. R. & Leventhal, A. M. (2014). Depression and anxiety symptoms moderate the relation between negative reinforcement smoking outcome expectancies and nicotine dependence. Journal of Studies on Alcohol and Drugs, 75(5), 775–780.Google Scholar
Parrish, K. H., Atherton, O. E., Quintana, A., Conger, R. D. & Robins, R. W. (2016). Reciprocal relations between internalizing symptoms and frequency of alcohol use: findings from a longitudinal study of Mexican-origin youth. Psychology of Addictive Behaviors, 30(2), 203.Google Scholar
Peechatka, A. L., Whitton, A. E., Farmer, S. L., Pizzagalli, D. A. & Janes, A. C. (2015). Cigarette craving is associated with blunted reward processing in nicotine-dependent smokers. Drug and Alcohol Dependence, 155, 202–207.CrossRefGoogle ScholarPubMed
Peters, E. N., Bae, D., Barrington-Trimis, J. L., Jarvis, B. P. & Leventhal, A. M. (2018). Prevalence and sociodemographic correlates of adolescent use and polyuse of combustible, vaporized, and edible cannabis products. JAMA Network Open, 1(5), e182765.CrossRefGoogle ScholarPubMed
Pettorruso, M., Martinotti, G., Fasano, A., et al. (2014). Anhedonia in Parkinson's disease patients with and without pathological gambling: a case-control study. Psychiatry Research, 215(2), 448–452.Google Scholar
Piper, M. E., Vasilenko, S. A., Cook, J. W. & Lanza, S. T. (2017). What a difference a day makes: differences in initial abstinence response during a smoking cessation attempt. Addiction, 112(2), 330–339.Google Scholar
Powers, J. M., Carroll, A. J., Veluz-Wilkins, A. K., et al. (2016). Is the effect of anhedonia on smoking cessation greater for women versus men? Nicotine & Tobacco Research, 19(1), 119–123.Google Scholar
Pozzi, G., Martinotti, G., Reina, D., et al. (2008). The assessment of post-detoxification anhedonia: influence of clinical and psychosocial variables. Substance Use & Misuse, 43(5), 722–732.Google Scholar
Rømer Thomsen, K. (2015). Measuring anhedonia: impaired ability to pursue, experience, and learn about reward. Frontiers in Psychology, 6, 1409.Google Scholar
Roys, M., Weed, K., Carrigan, M. & MacKillop, J. (2016). Associations between nicotine dependence, anhedonia, urgency and smoking motives. Addictive Behaviors, 62, 145–151.CrossRefGoogle ScholarPubMed
Schlaepfer, T. E., Cohen, M. X., Frick, C., et al. K (2008). Deep brain stimulation to reward circuitry alleviates anhedonia in refractory major depression. Neuropsychopharmacology, 33(2), 368.Google Scholar
Schmitz, J. M., Mooney, M. E., Moeller, F. G., et al. (2008). Levodopa pharmacotherapy for cocaine dependence: choosing the optimal behavioral therapy platform. Drug and Alcohol Dependence, 94(1–3), 142–150.Google Scholar
Seligman, M. E., Rashid, T. & Parks, A. C. (2006). Positive psychotherapy. American Psychologist, 61(8), 774.Google Scholar
Seney, M. L. & Sibille, E. (2014). Sex differences in mood disorders: perspectives from humans and rodent models. Biology of Sex Differences, 5(1), 17.Google Scholar
Seth, P., Rudd, R. A., Noonan, R. K. & Haegerich, T. M. (2018). Quantifying the epidemic of prescription opioid overdose deaths. American Journal of Public Health, 108(4), 500–502.Google Scholar
Snaith, P. (1993). Anhedonia: a neglected symptom of psychopathology. Psychological Medicine, 23(4), 957–966.Google Scholar
Snaith, R. P., Hamilton, M., Morley, S., et al. (1995). A scale for the assessment of hedonic tone the Snaith–Hamilton Pleasure Scale. The British Journal of Psychiatry, 167(1), 99–103.Google Scholar
Stevens, A., Peschk, I. & Schwarz, J. (2007). Implicit learning, executive function and hedonic activity in chronic polydrug abusers, currently abstinent polydrug abusers and controls. Addiction, 102(6), 937–946.Google Scholar
Stone, M. D., Audrain-McGovern, J. & Leventhal, A. M. (2017). Association of anhedonia with adolescent smoking susceptibility and initiation. Nicotine & Tobacco Research, 19(6), 738–742.Google Scholar
Sussman, N. & DeJong, S. M. (2018). Ethical considerations for mental health clinicians working with adolescents in the digital age. Current Psychiatry Reports, 20(12), 113.Google Scholar
Thomas, E. A. & Garland, E. L. (2017). Mindfulness is associated with increased hedonic capacity among chronic pain patients receiving extended opioid pharmacotherapy. The Clinical Journal of Pain, 33(2), 166.Google Scholar
Tomarken, A. J., Dichter, G. S., Freid, C., Addington, S. & Shelton, R. C. (2004). Assessing the effects of bupropion SR on mood dimensions of depression. Journal of Affective Disorders, 78(3), 235–241.CrossRefGoogle ScholarPubMed
Treadway, M. T. & Zald, D. H. (2011). Reconsidering anhedonia in depression: lessons from translational neuroscience. Neuroscience & Biobehavioral Reviews, 35(3), 537–555.Google Scholar
Tremblay, L. K., Naranjo, C. A., Cardenas, L., Herrmann, N. & Busto, U. E. (2002). Probing brain reward system function in major depressive disorder: altered response to dextroamphetamine. Archives of General Psychiatry, 59(5), 409–416.Google Scholar
Tremblay, L. K., Naranjo, C. A., Graham, S. J., et al. (2005). Functional neuroanatomical substrates of altered reward processing in major depressive disorder revealed by a dopaminergic probe. Archives of General Psychiatry, 62(11), 1228–1236.Google Scholar
van Roekel, E., Bennik, E. C., Bastiaansen, J. A., et al. (2016). Depressive symptoms and the experience of pleasure in daily life: an exploration of associations in early and late adolescence. Journal of Abnormal Child Psychology, 44(5), 999–1009.Google Scholar
Vivolo-Kantor, A. M., Seth, P., Gladden, R. M., et al. (2018). Vital signs: trends in emergency department visits for suspected opioid overdoses – United States, July 2016–September 2017. Morbidity and Mortality Weekly Report, 67(9), 279.Google Scholar
Voce, A., McKetin, R., Burns, R., Castle, D. & Calabria, B. (2018). The relationship between illicit amphetamine use and psychiatric symptom profiles in schizophrenia and affective psychoses. Psychiatry Research, 265, 19–24.CrossRefGoogle ScholarPubMed
Wardle, M. C., Vincent, J. N., Suchting, R., et al. (2017). Anhedonia is associated with poorer outcomes in contingency management for cocaine use disorder. Journal of Substance Abuse Treatment, 72, 32–39.Google Scholar
Wise, R. A. (2008). Dopamine and reward: the anhedonia hypothesis 30 years on. Neurotoxicity Research, 14(2–3), 169–183.Google Scholar
Witkiewitz, K., Bowen, S., Harrop, E. N., et al. (2014). Mindfulness-based treatment to prevent addictive behavior relapse: theoretical models and hypothesized mechanisms of change. Substance Use & Misuse, 49(5), 513–524.Google Scholar

Save book to Kindle

To save this book to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×