A criminal confession typically ends in conviction, raising a critically important question: Why do suspects decide to confess to their guilt against their own self-interests? The authors of this chapter answer this question by reviewing a large body of theoretical and empirical research related to decision-making involving confessions. Major topics covered include the distinction between different types of confessions, the Reid technique, Miranda waiver decisions, psychological and dispositional vulnerabilities that encourage a confession decision, and interrogation reforms and their impact on confessions and interrogations. The core message of the chapter is that the dominant method of police interrogation used in North America relies on well-established social influence tactics that cause suspects to perceive a confession as a rational decision under the circumstances. The authors examine research involving these tactics and their effects on interrogations and confessions, along with laws and policies that regulate interviews and interrogations of suspects in custody.