This essay unpacks the strategic role of race in Titus Andronicus and brings to light the play’s earnest representation of racism’s entanglement in the demands of the global capitalist project born in Shakespeare’s time. Titus Andronicus dreams of London as a cosmopolitan capital with imperial aspirations in a proto-colonial world-economy. In the possible futures that the play dreams up for England, prescribing the most profitable forms of intercultural trafficking is a priority. The smart device used for establishing such prescriptions is called race. The racial regime ushered in by early modern globalization, triggered by colonization, and forged in the furnace of early capitalism, was predicated not upon the elimination of racialized others, but on their strategic and contingent inclusion at inferior ranks in a hierarchical multicultural society. Titus Andronicus dramatizes the push and pull between the exclusion and inclusion of racialized Others necessary to the growth of early modern world-economies.