This chapter explores issues for Islam in relation to religious themes arising from developments in artificial intelligence (AI), conceived both as a philosophical and scientific quest to understand human intelligence and as a technological enterprise to instrumentalise it for commercial or political purposes. The monotheistic teachings of Islam are outlined to identify themes in AI that relate to central questions in the Islamic context and to addresses nuances of Islamic belief that differentiate it from the other Abrahamic traditions in consideration of AI. This chapter draws together the existing sparse literature on the subject, including notable applications of AI in Islamic contexts, and draws attention to the role of the Muslim world as a channel and expositor of knowledge between the ancient and modern world in the pre-history of AI. The chapter provides foundations for future scholarship on Islam and AI and a resource for wider scholarship on the religious, societal and cultural significance of AI.