Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-6bf8c574d5-j5c6p Total loading time: 0 Render date: 2025-03-09T15:56:54.971Z Has data issue: false hasContentIssue false

16 - In vitro growth and differentiation of oocytes

from Section 3 - Developmental biology

Published online by Cambridge University Press:  05 October 2013

By
Hang Yin  and
Roger Gosden
Edited by
Alan Trounson ,
Roger Gosden  and
Ursula Eichenlaub-Ritter
Hang Yin
Affiliation:
Center for Reproductive Medicine and Infertility, Weill Medical College of Cornell University, NewYork, NY, USA
Roger Gosden
Affiliation:
Jamestowne Bookworks,Williamsburg, VA, USA
Alan Trounson
Affiliation:
California Institute for Regenerative Medicine
Roger Gosden
Affiliation:
Center for Reproductive Medicine and Infertility, Cornell University, New York
Ursula Eichenlaub-Ritter
Affiliation:
Universität Bielefeld, Germany
Get access

Summary

A summary is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Chapter
Information
Biology and Pathology of the Oocyte
Role in Fertility, Medicine and Nuclear Reprograming
 , pp. 187 - 199
Publisher: Cambridge University Press
Print publication year: 2013

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Gosden, R, Lee, B.Portrait of an oocyte: our obscure origin. J Clin Invest 2010; 120: 973–83.CrossRefGoogle ScholarPubMed
Edwards, RG. Maturation in vitro of mouse, sheep, cow, pig, rhesus monkey and human ovarian oocytes. Nature 1965; 208: 349–51.CrossRefGoogle ScholarPubMed
Lambalk, CB, de Koning, CH, Flett, A, et al. Assessment of ovarian reserve. Ovarian biopsy is not a valid method for the prediction of ovarian reserve. Hum Reprod 2004; 19: 1055–9.CrossRefGoogle Scholar
Manabe, N, Goto, Y, Matsuda-Minehata, F, et al. Regulation mechanism of selective atresia in porcine follicles: regulation of granulosa cell apoptosis during atresia. J Reprod Dev 2004; 50: 493–514.CrossRefGoogle ScholarPubMed
Eppig, JJ, Schroeder, AC. Capacity of mouse oocytes from preantral follicles to undergo embryogenesis and development to live young after growth, maturation, and fertilization in vitro. Biol Reprod 1989; 41: 268–76.CrossRefGoogle ScholarPubMed
Roy, SK, Greenwald, GS. Hormonal requirements for the growth and differentiation of hamster preantral follicles in long-term culture. J Reprod Fertil 1989; 87: 103–14.CrossRefGoogle ScholarPubMed
Torrance, C, Telfer, E, Gosden, RG. Quantitative study of the development of isolated mouse pre-antral follicles in collagen gel culture. J Reprod Fertil 1989; 87: 367–74.CrossRefGoogle ScholarPubMed
Newton, H, Picton, H, Gosden, RG.In vitro growth of oocyte-granulosa cell complexes isolated from cryopreserved ovine tissue. J Reprod Fertil 1999; 115: 141–50.CrossRefGoogle ScholarPubMed
Telfer, EE, McLaughlin, M, Ding, C, et al. A two-step serum-free culture system supports development of human oocytes from primordial follicles in the presence of activin. Hum Reprod 2008; 23: 1151–8.CrossRefGoogle ScholarPubMed
McLaughlin, M, Telfer, EE. Oocyte development in bovine primordial follicles is promoted by activin and FSH within a two-step serum-free culture system. Reproduction 2010; 139: 971–8.CrossRefGoogle ScholarPubMed
Honda, A, Hirose, M, Inoue, K, et al. Large-scale production of growing oocytes in vitro from neonatal mouse ovaries. Int J Dev Biol 2009; 53: 605–13.CrossRefGoogle ScholarPubMed
Gosden, RG, Mullan, J, Picton, HM, et al. Current perspective on primordial follicle cryopreservation and culture for reproductive medicine. Hum Reprod Update 2002; 8:105–10.CrossRefGoogle ScholarPubMed
Picton, HM, Danfour, MA, Harris, SE, et al. Growth and maturation of oocytes in vitro. Reprod Suppl 2003; 61: 445–62.Google ScholarPubMed
Roy, SK, Greenwald, GS. An enzymatic method for dissociation of intact follicles from the hamster ovary: histological and quantitative aspects. Biol Reprod 1985; 32: 203–15.CrossRefGoogle ScholarPubMed
Eppig, JJ, Downs, SM. The effect of hypoxanthine on mouse oocyte growth and development in vitro: maintenance of meiotic arrest and gonadotropin-induced oocyte maturation. Dev Biol 1987; 119: 313–21.CrossRefGoogle ScholarPubMed
Lazzari, G, Galli, C, Moor, RM. Centrifugal elutriation of porcine oocytes isolated from the ovaries of newborn piglets. Anal Biochem 1992; 200: 31–5.CrossRefGoogle ScholarPubMed
Oktay, K, Nugent, D, Newton, H, et al. Isolation and characterization of primordial follicles from fresh and cryopreserved human ovarian tissue. Fertil Steril 1997; 67: 481–6.CrossRefGoogle ScholarPubMed
Telfer, EE, McLaughlin, M.In vitro development of ovarian follicles. Semin Reprod Med 2011; 29: 15–23.CrossRefGoogle ScholarPubMed
Dolmans, MM, Michaux, N, Camboni, A, et al. Evaluation of Liberase, a purified enzyme blend, for the isolation of human primordial and primary ovarian follicles. Hum Reprod 2006; 21: 413–20.CrossRefGoogle ScholarPubMed
Kristensen, SG, Rasmussen, A, Byskov, AG, et al. Isolation of pre-antral follicles from human ovarian medulla tissue. Hum Reprod 2011; 26: 157–66.CrossRefGoogle ScholarPubMed
Roy, SK, Greenwald, GS. Methods of separation and in-vitro culture of pre-antral follicles from mammalian ovaries. Hum Reprod Update 1996; 2: 236–45.CrossRefGoogle ScholarPubMed
Roy, SK, Treacy, BJ.Isolation and long-term culture of human preantral follicles. Fertil Steril 1993; 59: 783–90.CrossRefGoogle ScholarPubMed
Shikanov, A, Xu, M, Woodruff, TK, et al. A method for ovarian follicle encapsulation and culture in a proteolytically degradable 3 dimensional system. J Vis Exp 2011; (49): .
Desai, N, Abdelhafez, F, Calabro, A, et al. Three dimensional culture of fresh and vitrified mouse pre-antral follicles in a hyaluronan-based hydrogel: a preliminary investigation of a novel biomaterial for in vitro follicle maturation. Reprod Biol Endocrinol 2012; 10: 29.CrossRefGoogle Scholar
Nayudu, PL, Osborn, SM.Factors influencing the rate of preantral and antral growth of mouse ovarian follicles in vitro. J Reprod Fertil 1992; 95: 349–62.CrossRefGoogle ScholarPubMed
Boland, NI, Humpherson, PG, Leese, HJ, et al. Pattern of lactate production and steroidogenesis during growth and maturation of mouse ovarian follicles in vitro. Biol Reprod 1993; 48: 798–806.CrossRefGoogle ScholarPubMed
Spears, N, Boland, NI, Murray, AA, et al. Mouse oocytes derived from in vitro grown primary ovarian follicles are fertile. Hum Reprod 1994; 9: 527–32.CrossRefGoogle ScholarPubMed
Cortvrindt, R, Smitz, J, Van Steirteghem, AC. In-vitro maturation, fertilization and embryo development of immature oocytes from early preantral follicles from prepubertal mice in a simplified culture system. Hum Reprod 1996; 11: 2656–66.CrossRefGoogle Scholar
Cortvrindt, R, Hu, Y, Smitz, J.Recombinant luteinizing hormone as a survival and differentiation factor increases oocyte maturation in recombinant follicle stimulating hormone-supplemented mouse preantral follicle culture. Hum Reprod 1998; 13: 1292–302.CrossRefGoogle ScholarPubMed
Hu, Y, Cortvrindt, R, Smitz, J.Effects of aromatase inhibition on in vitro follicle and oocyte development analyzed by early preantral mouse follicle culture. Mol Reprod Dev 2002; 61: 549–59.CrossRefGoogle ScholarPubMed
Muruvi, W, Picton, HM, Rodway, RG, et al. In vitro growth of oocytes from primordial follicles isolated from frozen-thawed lamb ovaries. Theriogenology 2005; 64: 1357–70.CrossRefGoogle ScholarPubMed
Hornick, JE, Duncan, FE, Shea, LD, et al. Isolated primate primordial follicles require a rigid physical environment to survive and grow in vitro. Hum Reprod 2012; 27: 1801–10.CrossRefGoogle ScholarPubMed
Eppig, JJ, O’Brien, MJ. Development in vitro of mouse oocytes from primordial follicles. Biol Reprod 1996; 54: 197–207.CrossRefGoogle ScholarPubMed
Nilsson, EE, Skinner, MK. Kit ligand and basic fibroblast growth factor interactions in the induction of ovarian primordial to primary follicle transition. Mol Cell Endocrinol 2004; 214: 19–25.CrossRefGoogle ScholarPubMed
Carlsson, IB, Laitinen, MP, Scott, JE, et al. Kit ligand and c-Kit are expressed during early human ovarian follicular development and their interaction is required for the survival of follicles in long-term culture. Reproduction 2006; 131: 641–9.CrossRefGoogle ScholarPubMed
Telfer, EE, McLaughlin, M.Strategies to support human oocyte development in vitro. Int J Dev Biol 2013; 56: 901–7.CrossRefGoogle Scholar
Li, J, Kawamura, K, Cheng, Y, et al. Activation of dormant ovarian follicles to generate mature eggs. Proc Natl Acad Sci USA 2010; 107: 10280–4.CrossRefGoogle ScholarPubMed
Harris, SE, Leese, HJ, Gosden, RG, et al. Pyruvate and oxygen consumption throughout the growth and development of murine oocytes. Mol Reprod Dev 2009; 76: 231–8.CrossRefGoogle ScholarPubMed
Murray, AA, Molinek, MD, Baker, SJ, et al. Role of ascorbic acid in promoting follicle integrity and survival in intact mouse ovarian follicles in vitro. Reproduction 2001; 121: 89–96.CrossRefGoogle ScholarPubMed
Hirao, Y, Itoh, T, Shimizu, M, et al. In vitro growth and development of bovine oocyte-granulosa cell complexes on the flat substratum: effects of high polyvinylpyrrolidone concentration in culture medium. Biol Reprod 2004; 70: 83–91.CrossRefGoogle ScholarPubMed
Eppig, JJ, O’Brien, MJ, Pendola, FL, et al. Factors affecting the developmental competence of mouse oocytes grown in vitro: follicle-stimulating hormone and insulin. Biol Reprod 1998; 59: 1445–53.CrossRefGoogle ScholarPubMed
Spears, N, Murray, AA, Allison, V, et al. Role of gonadotrophins and ovarian steroids in the development of mouse follicles in vitro. J Reprod Fertil 1998; 113: 19–26.CrossRefGoogle ScholarPubMed
Boland, NI, Gosden, RG.Effects of epidermal growth factor on the growth and differentiation of cultured mouse ovarian follicles. J Reprod Fertil 1994; 101: 369–74.CrossRefGoogle ScholarPubMed
Murray, AA, Swales, AK, Smith, RE, et al. Follicular growth and oocyte competence in the in vitro cultured mouse follicle: effects of gonadotrophins and steroids. Mol Hum Reprod 2008; 14: 75–83.CrossRefGoogle ScholarPubMed
Smitz, J, Cortvrindt, R, Van Steirteghem, AC.Normal oxygen atmosphere is essential for the solitary long-term culture of early preantral mouse follicles. Mol Reprod Dev 1996; 45: 466–75.3.0.CO;2-P>CrossRefGoogle ScholarPubMed
Cecconi, S, Barboni, B, Coccia, M, et al. In vitro development of sheep preantral follicles. Biol Reprod 1999; 60: 594–601.CrossRefGoogle ScholarPubMed
Gigli, I, Byrd, DD, Fortune, JE. Effects of oxygen tension and supplements to the culture medium on activation and development of bovine follicles in vitro. Theriogenology 2006; 66: 344–53.CrossRefGoogle ScholarPubMed
Hirao, Y, Shimizu, M, Iga, K, et al. Optimization of oxygen concentration for growing bovine oocytes in vitro: constant low and high oxygen concentrations compromise the yield of fully grown oocytes. J Reprod Dev 2012; 58: 204–11.CrossRefGoogle ScholarPubMed
Hunter, RH, Grøndahl, C, Greve, T, et al. Graafian follicles are cooler than neighbouring ovarian tissues and deep rectal temperatures. Hum Reprod 1997; 12: 95–100.CrossRefGoogle ScholarPubMed
Liu, J, Rybouchkin, A, Van der Elst, J, et al. Fertilization of mouse oocytes from in vitro-matured preantral follicles using classical in vitro fertilization or intracytoplasmic sperm injection. Biol Reprod 2002; 67: 575–9.CrossRefGoogle ScholarPubMed
Adriaens, I, Cortvrindt, R, Smitz, J.Differential FSH exposure in preantral follicle culture has marked effects on folliculogenesis and oocyte developmental competence. Hum Reprod 2004; 19: 398–408.CrossRefGoogle ScholarPubMed
Xu, M, Kreeger, PK, Shea, LD, et al. Tissue-engineered follicles produce live, fertile offspring. Tissue Eng 2006; 12: 2739–46.CrossRefGoogle ScholarPubMed
O’Brien, MJ, Pendola, JK, Eppig, JJ. A revised protocol for in vitro development of mouse oocytes from primordial follicles dramatically improves their developmental competence. Biol Reprod 2003; 68: 1682–6.CrossRefGoogle ScholarPubMed
Wandji, SA, Srsen, V, Nathanielsz, PW, et al. Initiation of growth of baboon primordial follicles in vitro. Hum Reprod 1997; 12: 1993–2001.CrossRefGoogle ScholarPubMed
Picton, HM, Gosden, RG. In vitro growth of human primordial follicles from frozen-banked ovarian tissue. Mol Cell Endocrinol 2000; 166: 27–35.CrossRefGoogle ScholarPubMed
Pan, H, O’Brien, MJ, Wigglesworth, K, et al. Transcript profiling during mouse oocyte development and the effect of gonadotropin priming and development in vitro. Dev Biol 2005; 286: 493–506.CrossRefGoogle ScholarPubMed
Xu, M, Barrett, SL, West-Farrell, E, et al. In vitro grown human ovarian follicles from cancer patients support oocyte growth. Hum Reprod 2009; 24: 2531–40.CrossRefGoogle ScholarPubMed
Xu, J, Xu, M, Bernuci, MP, et al. Primate follicular development in vitro. In: Kim, S, ed. Oocyte Biology in Fertility Preservation. New York, NY: Springer Science Business Media. 2013 (in press).Google Scholar
Nayudu, PL, Wu, J, Michelmann, HW.In vitro development of marmoset monkey oocytes by pre-antral follicle culture. Reprod Domest Anim 2003; 38: 90–6.CrossRefGoogle ScholarPubMed
Ting, AY, Yeoman, RR, Lawson, MS, et al. In vitro development of secondary follicles from cryopreserved rhesus macaque ovarian tissue after slow-rate freeze or vitrification. Hum Reprod 2011; 26: 2461–72.CrossRefGoogle ScholarPubMed
Nogueira, D, Sadeu, JC, Montagut, J. In vitro oocyte maturation: current status. Semin Reprod Med 2012; 30: 199–213.Google ScholarPubMed
Mainigi, MA, Ord, T, Schultz, RM.Meiotic and developmental competence in mice are compromised following follicle development in vitro using an alginate-based culture system. Biol Reprod 2011; 85: 269–76.CrossRefGoogle ScholarPubMed
Anckaert, E, De Rycke, M, Smitz, J.Culture of oocytes and risk of imprinting defects. Hum Reprod Update 2013; 19: 52–66.CrossRefGoogle ScholarPubMed
Hübner, K, Fuhrmann, G, Christenson, LK, et al. Derivation of oocytes from mouse embryonic stem cells. Science 2003; 300: 1251–6.CrossRefGoogle ScholarPubMed
Geijsen, N, Horoschak, M, Kim, K, et al. Derivation of embryonic germ cells and male gametes from embryonic stem cells. Nature 2004; 427: 148–54.CrossRefGoogle ScholarPubMed
Nicholas, CR, Haston, KM, Grewall, AK, et al. Transplantation directs oocyte maturation from embryonic stem cells and provides a therapeutic strategy for female infertility. Hum Mol Genet 2009; 18: 4376–89.CrossRefGoogle ScholarPubMed
Hayashi, K, Ogushi, S, Kurimoto, K, et al. Offspring from oocytes derived from in vitro primordial germ cell-like cells in mice. Science 2012; 338: 971–5.CrossRefGoogle ScholarPubMed
Huang, Y, Osorno, R, Tsakiridis, A, et al. In vivo differentiation potential of epiblast stem cells revealed by chimeric embryo formation. Cell Rep 2012; 2: 1571–8.CrossRefGoogle ScholarPubMed
Tachibana, M, Amato, P, Sparman, M, et al. Human embryonic stem cells derived by somatic cell nuclear transfer. Cell 2013; 153: 1228–38.CrossRefGoogle ScholarPubMed
Zuckerman, S.The number of oocytes in the mature ovary. Recent Prog Horm Res 1951; 6: 63–109.Google Scholar
Johnson, J, Canning, J, Kaneko, T, et al. Germline stem cells and follicular renewal in the postnatal mammalian ovary. Nature 2004; 428: 145–50.CrossRefGoogle ScholarPubMed
Zou, K, Yuan, Z, Yang, Z, et al. Production of offspring from a germline stem cell line derived from neonatal ovaries. Nat Cell Biol 2009; 11: 631–6.CrossRefGoogle ScholarPubMed
White, YA, Woods, DC, Takai, Y, et al. Oocyte formation by mitotically active germ cells purified from ovaries of reproductive-age women. Nat Med 2012; 18: 413–21.CrossRefGoogle ScholarPubMed
Dyce, PW, Wen, L, Li, J.In vitro germline potential of stem cells derived from fetal porcine skin. Nat Cell Biol 2006; 8: 384–90.CrossRefGoogle ScholarPubMed
Virant-Klun, I, Zech, N, Rožman, P, et al. Putative stem cells with an embryonic character isolated from the ovarian surface epithelium of women with no naturally present follicles and oocytes. Differentiation 2008; 76: 843–56.CrossRefGoogle ScholarPubMed

Save book to Kindle

To save this book to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×