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20 - Lifestyle, diet, and exercise in polycystic ovary syndrome

from Section 4 - The tool kit

Published online by Cambridge University Press:  05 July 2015

By
Elizabeth Burt  and
Rina Agrawal
Edited by
Leo Plouffe, Jr  and
Botros R. M. B. Rizk
Leo Plouffe, Jr
Affiliation:
Bayer Healthcare, Wayne, New Jersey
Botros R. M. B. Rizk
Affiliation:
University of South Alabama
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Androgens in Gynecological Practice , pp. 208 - 215
Publisher: Cambridge University Press
Print publication year: 2015

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References

1.World Health Organization (WHO). (2002) Current practices and controversies in assisted reproduction: a report of a WHO meeting on medical, ethical and social aspects of assisted reproduction.Google Scholar
2.Grainger, DA, Frazier, LM, Rowland, CA. (2006) Preconception care and treatment with assisted reproductive technologies. Matern Child Health J 10:S161–164.CrossRefGoogle ScholarPubMed
3.Barrett, JR. (2006) Fertile grounds of inquiry: environmental effects on human reproduction. Environ Health Perspect 114:A644–649.Google Scholar
4.Moran, L, Hutchinson, S, Norma, R, Teede, H. (2011) Lifestyle changes in women with polycystic ovary syndrome, Cochrane Database Syst Rev 2:CD007506.Google Scholar
5.NHS. Statistics on obesity, physical activity and diet: England, 2011.Google Scholar
6.World Health Organization (WHO). Consultation on Obesity (2000) Obesity: preventing and managing the global epidemic. WHO technical report series 894. Geneva: World Health Organization.Google Scholar
7.Pandey, S, Pandey, S, Maheshwari, A, Bhattacharya, S. (2010) The impact of female obesity on the outcome of fertility treatment. J Hum Reprod Sci 3(2):62–67.Google ScholarPubMed
8.McCartney, C, Blank, S, Prendergast, K. (2007) Obesity and sex steroid changes across puberty: evidence for marked hyperandrogenaemia in pre- and early pubertal obese girls. J Clin Endocrinol Metab 92:5588–5595.CrossRefGoogle Scholar
9.Alvarez-Blasco, F, Botella-Carretero, J, San Millan, J, Escobar-Morreale, H (2006) Prevalence and characteristics of the polycystic ovary syndrome in over-weight and obese women. Arch Intern Med 166(19):2081–2086.Google Scholar
10.Yildiz, B, Knochenhauer, E, Azziz, R. (2008) Impact of obesity on the risk for polycystic ovary syndrome. J Clin Endocrinol Metab 93(1):162–168.CrossRefGoogle ScholarPubMed
11.Maloney, C.A, Rees, W.D. (2005) Gene–nutrient interactions during fetal development. Reproduction 130(4):401–410.Google Scholar
12.Cresswell, J, Barker, D, Osmomnd, C, Egger, P, Phillips, D, Fraser, R. (1997) Fetal growth, length of gestation, and polycystic ovaries in later life. Lancet 350:1131–1135.CrossRefGoogle Scholar
13.Kent, S, Gnatuk, C, Kunselman, A. (2008) Hyperandrogenism and hyperinsulinaemia in children of women with PCOS: a controlled study. J Clin Endocrinol Metab 93:1662–1669.CrossRefGoogle ScholarPubMed
14.Robinson, J, Forsdike, R, Taylor, J. (1999) In utero exposure of female lambs to testosterone reduces the sensitivity of the gonadotropin-releasing hormone neuronal network to inhibition to progesterone. Endocrinology 140:5797–5805.Google Scholar
15.Abbott, D, Tarantal, A, Dumesic, D. (2009) Fetal, infant, adolescent and adult phenotypes of polycystic ovary syndrome in prenatally androgenized female rhesus monkeys. Am J Primatol.71:776–784.Google Scholar
16.Pasquali, R, Stener-Victorin, E, Yildiz, B, Duleba, A, Hoeger, K, Mason, H, Homberg, R, Hickey, T, franks, S, Tapamaien, J, Balan, A, Abbott, D, Diamanti-Kandarakis, E, Legro, R. (2011) PCOS Forum: research in polycystic ovary syndrome today and tomorrow. Clin Endocrinol. 74:424–433.CrossRefGoogle ScholarPubMed
17.Anderson, H, Fogel, N, Grebe, S (2010) Infants of women with polycystic ovary syndrome have lower cord blood androstenedione and estradiol levels. J Clin Endocrinol Metab 61:946–951.Google Scholar
18.Badawy, A, Elnashar, A. (2011) Treatment options for polycystic ovary syndrome. Int J Women’s Health 3:25–35.CrossRefGoogle ScholarPubMed
19.Tamer, Erel C, Senturk, L (2009). The impact of body mass on assisted reproduction. Curr Opin Obstet Gynaecol 21:228–235.Google Scholar
20.Pasquali, R, Gambineri, A, Pagotto, U. (2006) The impact of obesity on reproduction with polycystic ovary syndrome. BJOG 113:1148–1159.CrossRefGoogle ScholarPubMed
21.Lord, J, Thomas, R, Fox, B, Acharya, U, Wilkin, T. (2006) The central issue? Visceral fat mass is a good marker of insulin resistance in polycystic ovary syndrome. BJOG 113:1203–1209.Google Scholar
22.Hutchison, S, Stepto, N, Harrison, C, Moran, L, Strauss, B, Teede, H. (2011) Effect of exercise on insulin resistance and body composition in overweight and obese women with and without polycystic ovary syndrome. J Clin Endocrinol Metab 96(1):E48–E56.Google Scholar
23.Park, H, Lee, K (2005) Greater beneficial effects of visceral fat reduction compared with subcutaneous fat reduction on parameters of the metabolic syndrome: a study of weight reduction programmes in subjects with visceral and subcutaneous obesity. Diabet Med 2005 22:266–272.Google Scholar
24.Kuchenbecker, W, Groen, H, Van Asselt, S, Bolster, J, Zwerver, J, Slart, R, VdJagt, E, Land, J, Hoek, A. (2011) In women with polycystic ovary syndrome and obesity, loss of intra abdominal fat is associated with resumption of ovulation. Hum Reprod 26(9):2505–2512.Google Scholar
25.Kirschner, M, Samojlik, E, Drejka, M, Szmal, E, Schneider, G, Ertel, N (1990) Androgen-estrogen metabolism in women with upper body versus lower body obesity. J Clin Endocrinol Metab 70:473–479.Google Scholar
26.Rodin, A, Thakkar, H, Taylor, N. (1994) Hyperandrogenism on polycystic ovary syndrome. Evidence of dysregulation of 11 beta-hydroxysteroid dehydrogenase. N Engl J Med 330:460–465.Google Scholar
27.Stewart, P, Shackleton, C, Beastall, G. (1990) 5 alpha –reductase activity in polycystic ovary syndrome. Lancet 335:431–433.Google Scholar
28.Gambineri, A, Forlani, G, Murnarini, A. (2009) Increased clearance of cortisol by 5 beta–reductase in a subset of women with adrenal hyperandrogenism in polycystic ovary syndrome. J Endocrinol Invest 32:210–218.CrossRefGoogle Scholar
29.Carmina, E, Bucchieri, S, Mansueto, P, Rini, G, Ferin, M, Lobo, R. (2009) Circulating levels of adipose products and differences in fat distribution in the ovulatory and anovulatory phenotypes of polycystic ovary syndrome. Fertil Steril 91:1332–1335.Google Scholar
30.Hahn, S, Haselhorst, U, Quasbeck, D, Tan, S, Kimming, R, Mann, K, Janssen, O. (2006) Decreased soluble leptin receptor levels in women with polycystic ovary syndrome. Eur J Endocrinol 154:287–294.Google Scholar
31.Gosman, G, Kathcher, H, Legro, RS. (2006) Obesity and the role of gut adipose hormones in female reproduction. Hum Reprod Update 12:585–601.Google Scholar
32.Pasquali, R, Gambineri, A. (2006) Metabolic effects of obesity on reproduction. Reprod Biomed Online 12:542–511.Google Scholar
33.Rich-Edwards, J, Goldman, M, Willett, W, Hunter, D, Stampfer, M, Colditz, G. (1994) Adolescent body mass index and infertility caused by ovulatory disorder. Am J Obstet Gynecol 171:171–7.CrossRefGoogle ScholarPubMed
34.Grodstein, F, Goldman, M, Cramer, D. (1994) Body mass index and ovulatory infertility. Epidemiology 5:247–250.Google Scholar
35.Kiddy, D, Hamilton-Fairley, D, Bush, A, Short, F, Anyaoku, V, Reed, M, Franks, S. (1992) Improvement in endocrine and ovarian function during dietary treatment of obese women with polycystic ovary syndrome. Clin Endocrinol 36:105–111.Google Scholar
36.Balen, A, Homberg, R, Franks, S (2009) Defining polycystic ovary syndrome. BMJ 338:a2968.CrossRefGoogle ScholarPubMed
37.Willis, D, Mason, H, Gilling-Smith, C, Frans, S. (1996) Modulation by insulin of follicle stimulating hormone and luteinizing hormone actions in human granulosa cells of normal and polycystic ovaries. J Clin Endocrinol Metab 81:302–309.Google Scholar
38.Brewer, C, Balan, A. (2010) The adverse effects of obesity on conception and implantation. Reproduction 140:347–364.Google Scholar
39.Levens, E, Skarulis, M. (2008) Assessing the role of endometrial alteration among obese women undergoing assisted reproduction. Fertil Steril 89:1606–1608.Google Scholar
40.Department of Health. (2009) Regulated fertility services: a commissioning aid.Google Scholar
41.Jungheim, E, Lanzendorf, S, Odem, R, Moley, K, Chang, A, Ratts, V (2009) Morbid obesity is associated with lower clinical pregnancy rates after in vitro fertilization in women with polycystic ovary syndrome. Fertil Steril 92:256–261.Google Scholar
42.Sonino, N, Fava, G, Mani, E. (1993) Quality of life in hirsute women. Postgrad Med J 69:615–661.Google Scholar
43.Gambineri, A, Pelusi, C, Vicennati, V, Pagotto, U, Pasquali, R. (2002) Obesity and the polycystic ovary syndrome. Int J Obes Rel Metab Disord 26:883–896.Google Scholar
44.Moran, L, Misso, ML, Wild, RA, Norman, RJ (2010) Impaired glucose tolerance, type 2 diabetes and metabolic syndrome in polycystic ovary syndrome: a systematic review and meta-analysis. Hum Reprod Update 16(4):347–363.Google Scholar
45.Janssen, O, Hahn, S, Tan, S, Benson, S, Elsenbruch, S. (2008) Mood and sexual function in polycystic ovary syndrome. Semin Reprod Med 26:45–52.Google Scholar
46.Coffey, S, Mason, H. (2003) The effect of polycystic ovary syndrome on health-related quality of life. Gynecol Endocrinol 17(5):379–386.Google Scholar
47.Lim, S, Norman, R, Clifton, P, Noakes, M. (2009) Hyperandrogenaemia, psychological stress and food craving in young women. Physiol Behav 98(3):276–280.Google Scholar
48.Benson, S, Arck, P, Tan, S, Hahn, S, Mann, K, Rifaie, N, Janssen, O, Schedlowski, M, Elenbruch, S. (2009) Disturbed stress responses in women with polycystic ovary syndrome. Psychoneuroendocrinology 34(5):727–735.Google Scholar
49.Deeks, A, Gibson-Helm, M, Teede, H.(2010) Anxiety and depression in polycystic ovary syndrome: a comprehensive investigation. Fertil Steril 93(7):2421–2423.Google Scholar
50.Cousineau, T, Domar, A (2007). Psychological impact of infertility. Best Pract Res Clin Obstet Gynaecol 21(2):293–308.Google Scholar
51.Moran, L, Pasquali, R, Teede, HJ, Hoeger, KM, Norman, RJ. (2009) Treatment of obesity in polycystic ovary syndrome: a position statement of the Androgen Excess and Polycystic Ovary Syndrome Society. Fertil Steril 92(6):1966–1982.Google Scholar
52.Nicholson, F, Rolland, C, Broom, J, Love, J. (2010) Effectiveness of long term (twelve months) nonsurgical weight loss interventions for obese women with polycystic ovary syndrome: a systematic review. Int J Women’s Health 2:393–399.Google Scholar
53.Crosignani, P, Colombo, M, Vegetti, W, Somigliana, E, Gessati, A, Ragni, G. (2003) Overweight and obese anovulatory patients with polycystic ovaries: parallel improvements in anthropometric indices, ovarian physiology and fertility rate induced by diet. Hum Reprod 18:1928–1932.Google Scholar
54.Nybacka, A, Carlstrom, K, Stahle, A, Nyren, S, Hellstrom, P, Hirschberg, A. (2011) Randomised comparison of the influence of dietary management and/or physical exercise on ovarian function and metabolic parameters in overweight women with polycystic ovary syndrome. Fertil Steril 96(6):1508–1513.CrossRefGoogle ScholarPubMed
55.Bennett, B, Sothern, MS. Diet, exercise, behavior: the promise and limits of lifestyle change. Semin Pediatr Surg 2009;18:152–158.CrossRefGoogle ScholarPubMed
56.Barr, S, Hart, K, Reeves, S, Sharp, K, Jeanes, Y. (2011) Habitual dietary intake, eating pattern and physical activity of women with polycystic ovary syndrome. Eur J Clin Nutr 65(10):1126–1132.Google Scholar
57.Reaven, G. (2005) The insulin resistance syndrome: definition and dietary approach to treatment. Annu Rev Nutr 25:391–406.Google Scholar
58.Diamanti-Kandarakis, E, Katsikis, I, Piperi, C. (2008) Increased serum advanced glycation end-products is a distinct finding in lean women with polycystic ovary syndrome (PCOS). Clin Endocrinol 69:634–641.Google Scholar
59.Gambineri, A, Pelusi, C, Genghini, S, Morselli-Labate, A, Cacciari, M, Pagotto, E. (2004) Effect of flutamide and metformin administered alone or in combination in dieting obese women with polycystic ovary syndrome. Clin Endocrinol (Oxf) 60:241–249.Google Scholar
60.Thomson, R, Buckley, J, Brinkworth, G. (2011) Exercise for the treatment and management of overweight women with polycystic ovary syndrome: a review of the literature. Obes Rev 12:e202–210.CrossRefGoogle ScholarPubMed
61.Lass, N, Kleber, M, Winkel, K, Wunsch, R, Reinehr, T. (2011) Effect of lifestyle intervention of features of polycystic ovarian syndrome, metabolic syndrome and intima-media thickness in obese adolescent girls. J Clin Endocrinol Metab 96(11):3533–3540.Google Scholar
62.Jan, S, Bellman, C, Barone, J, Jessen, L, Arnold, M. (2009) Shape it up: a school-based education programme to promote healthy eating and exercise development by a healthy plan in collaboration with a college of pharmacy. J Manag Care Pharma 15 (5):403–13.Google Scholar

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