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14B - IVF Should Be First-Line Treatment for Unexplained Infertility of Two Years Duration

Against

from Section III - The Best Policy

Published online by Cambridge University Press:  25 November 2021

Roy Homburg
Affiliation:
Homerton University Hospital, London
Adam H. Balen
Affiliation:
Leeds Centre for Reproductive Medicine
Robert F. Casper
Affiliation:
Mount Sinai Hospital, Toronto
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Summary

True scientific evidence is difficult to assemble when there are so many underlying interests. For the first time a comprehensive integrated analysis factoring in live births, risks and costs to deliver one baby shows how first line treatment should be intrauterine insemination (IUI) and not IVF.

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Chapter
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Publisher: Cambridge University Press
Print publication year: 2021

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References

Bahadur, G, Homburg, R, Bosmans, JE, et al. Observational retrospective study of UK national success, risks and costs for 319,105 IVF/ICSI and 30,669 IUI treatment cycles. BMJ Open. 2020;10:e034566.CrossRefGoogle Scholar
Zegers-Hochschild, F, Adamson, GD, de Mouzon, J, et al. International Committee for Monitoring Assisted Reproductive Technology (ICMART) and the World Health Organization (WHO) revised glossary of ART terminology, 2009. Fertil Steril. 2009 Nov;92(5):1520–24.CrossRefGoogle ScholarPubMed
Reindollar, RH, Regan, MM, Neumann, PJ, et al. A randomized clinical trial to evaluate optimal treatment for unexplained infertility: the fast track and standard treatment (FASTT) trial. Fertil Steril. 2010; 94:888–99.CrossRefGoogle ScholarPubMed
Hansen, KR. Gonadotropins with intrauterine insemination for unexplained infertility-time to stop? Fertil Steril. 2020 February;113(2):333–4.CrossRefGoogle ScholarPubMed
Ayeleke, RO, Asseler, JD, Cohlen, BJ, et al. Intra-uterine insemination for unexplained subfertility. Cochrane Database Syst Rev. 2020 March 3;3:CD001838. doi: 10.1002/14651858.CD001838.pub6.Google ScholarPubMed

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