This article addresses a 250-year episode of human colonisation, community growth and subsequent decline on the small Greek island of Antikythera (ad 1770 to present), focusing on rich documentary sources from four decades of British rule in the early nineteenth century. In particular, a series of nominal censuses and accompanying agricultural statistics can be combined with intensive landscape archaeological survey evidence to explore evidence for changing nineteenth-century households, household economies, and how these are manifest across an entire physical landscape. We also contextualise this well-recorded, most recent historical episode within the island's deeper population history stretching back at least seven millennia.