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Volume 197 - Issue 4 - October 2010

Contents

Page 2 of 2

Short Reports

  • Nalmefene in the treatment of pathological gambling: multicentre, double-blind, placebo-controlled study

  • Jon E. Grant, Brian L. Odlaug, Marc N. Potenza, Eric Hollander, Suck Won Kim
  • Published online by Cambridge University Press:
    02 January 2018, pp. 330-331
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  • Summary

    Pathological gambling is a disabling disorder experienced by about 1% of adults. We randomised 233 participants (41.6% women) 1:1:1 to nalmefene (20 or 40 mg) or placebo. In analyses performed using an intention-to-treat (ITT) population, nalmefene failed to show statistically significant differences from placebo on primary and secondary outcomes. Post hoc analyses of only participants who received a full titration of the medication for at least 1 week demonstrated that nalmefene 40 mg/day resulted in significantly greater reductions on the primary outcome measure. These findings suggest that medication dosing may be an important consideration in achieving symptom control.

Correspondence

Columns

  • Interpretation of ecological data

  • Daniel Vincent Riordan, Cameron Stark
  • Published online by Cambridge University Press:
    02 January 2018, p. 332
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  • Author's reply

  • Melissa Raven
  • Published online by Cambridge University Press:
    02 January 2018, p. 332
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  • Failure to communicate effectively or failure of feedback?

  • Raman D. Pattanayak, Sanjay K. Pattanayak
  • Published online by Cambridge University Press:
    02 January 2018, pp. 332-333
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  • Author's reply

  • Anthony F. Jorm
  • Published online by Cambridge University Press:
    02 January 2018, p. 333
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  • Cannabis and psychosis

  • Jonathan Ornstein
  • Published online by Cambridge University Press:
    02 January 2018, p. 333
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Book Reviews

Columns

  • Fiction's Madness. By Liam Clarke. PCCS Books. 2009. £18.99 (pb). 232pp. ISBN: 9781906254230

  • Allan Beveridge
  • Published online by Cambridge University Press:
    02 January 2018, pp. 337-338
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Columns

  • From the Editor's desk

  • Peter Tyrer
  • Published online by Cambridge University Press:
    02 January 2018, p. 340
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Front matter

  • BJP volume 197 issue 4 Cover and Front matter

  • Published online by Cambridge University Press:
    02 January 2018, pp. f1-f2
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