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9 - Therapeutic decision making in hematopoietic stem cell transplantation for multiple myeloma

Published online by Cambridge University Press:  31 July 2009

Reinhold Munker
Affiliation:
Louisiana State University
Hillard M. Lazarus
Affiliation:
University Hospitals Case Medical Center
Kerry Atkinson
Affiliation:
University of Queensland
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The BMT Data Book , pp. 139 - 156
Publisher: Cambridge University Press
Print publication year: 2009

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References

Attal, M, Harousseau, JL, Stoppa, AM, et al. 1996. A prospective, randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma. N Engl J Med 335: 91–97.CrossRefGoogle ScholarPubMed
Attal, M, Harousseau, JL, Facon, T, et al. 2003. Single versus double autologous stem-cell transplantation for multiple myeloma. N Engl J Med 349: 2495–502.CrossRefGoogle ScholarPubMed
Attal, M, Harousseau, JL, Leyvraz, S, et al. 2006. Maintenance therapy with thalidomide improves survival in patients with multiple myeloma. Blood 108: 3289–94.CrossRefGoogle ScholarPubMed
Barlogie, B, Kyle, RA, Anderson, KC, et al. 2006. Standard chemotherapy compared with high-dose chemoradiotherapy for multiple myeloma: Final results of phase III US Intergroup Trial S9321. J Clin Oncol 24: 929–36.CrossRefGoogle ScholarPubMed
Barlogie, B, Tricot, G, Anaissie, E, et al. 2006. Thalidomide and hematopoietic-cell transplantation for multiple myeloma. N Engl J Med 354: 1021–30.CrossRefGoogle ScholarPubMed
Blade, J, Rosinol, L, Sureda, A, et al. 2005. High-dose therapy intensification compared with continued standard chemotherapy in multiple myeloma patients responding to the initial chemotherapy: long-term results from a prospective randomized trial from the Spanish cooperative group PETHEMA. Blood 106: 3755–59.CrossRefGoogle ScholarPubMed
Bruno, B, Rotta, M, Patriarca, F, et al. 2006. A comparison of allografting with autografting for newly diagnosed myeloma. N Engl J Med 356: 1110–20.CrossRefGoogle Scholar
Cavo, M, Tossi, P, Zamagni, E, et al. 2007. Prospective, randomized study of single compared with double autologous stem-cell transplantation for multiple myeloma: Bologna 96 clinical study. J Clin Oncol 25: 2434–41.CrossRefGoogle ScholarPubMed
Child, JA, Morgan, GJ, Davies, FE, et al. 2003. High-dose chemotherapy with hematopoietic stem-cell rescue for multiple myeloma. N Engl J Med 348: 1875–83.CrossRefGoogle ScholarPubMed
Durie, BGM, Harousseau, JL, Miguel, JS, et al. 2006. International uniform response criteria for multiple myeloma. Leukemia 20: 1467–73.CrossRefGoogle ScholarPubMed
Durie, BGM, Jacobson, J, Barlogie, B, and Crowley, J. 2004. magnitude of response with myeloma frontline therapy does not predict outcome: Importance of time to progression in Southwest Oncology Group chemotherapy trials. J Clin Oncol 22: 1857–63.CrossRefGoogle ScholarPubMed
Facon, T, Mary, JY, Hulin, C, et al. 2005. Major superiority of melphalan-prednisone (MP) + thalidomide (THAL) over MP and autologous stem cell transplantation in the treatment of newly diagnosed elderly patients with multiple myeloma. Blood 106: abstract 780.Google Scholar
Fermand, JP, Katsahian, S, Divine, M, Leblond, V, Dreyfus, F, Macro, M. 2005. High-dose therapy and autologous blood stem-cell transplantation compared with conventional treatment in myeloma patients aged 55 to 65 years: Long-term results of a randomized control trial from the Group Myelome-Autogreffe. J Clin Oncol 23: 9227–33.CrossRefGoogle Scholar
Fermand, JP, Ravaud, P, Chevret, S, et al. 1998. High-dose therapy and autologous peripheral blood stem cell transplantation in multiple myeloma: Up-front or rescue treatment? Results of a multicenter sequential randomized clinical trial. Blood 92: 3131–36.Google ScholarPubMed
Garban, F, Attal, M, Michallet, M, et al. 2006. Prospective comparison of autologous stem cell transplantation followed by dose-reduced allograft (IFM99–03 trial) with tandem autologous stem cell transplantation (IFM99–04 trial) in high-risk de novo multiple myeloma. Blood 107: 3474–80.CrossRefGoogle Scholar
Kristinsson, SY, Landgren, O, Dickman, PW, Derolf, AR, Björkholm, M. 2007. Patterns of survival in multiple myeloma: a population-based study of patients diagnosed in Sweden from 1973 to 2003. J Clin Oncol 25: 1993–99.CrossRefGoogle ScholarPubMed
Moreau, P, Facon, T, Attal, M, Hulin, C, Michallet, M, Maloisel, F. 2002. Comparison of 200 mg/m2 melphalan and 8 Gy total body irradiation plus 140 mg/m2 melphalan as conditioning regimens for peripheral blood stem cell transplantation in patients with newly diagnosed multiple myeloma: final analysis of the Intergroupe Francophone du Myelome 9502 randomized trial. Blood 99: 731–35.CrossRefGoogle Scholar
Palumbo, A, Bringhan, S, Caravita, T, et al. 2006. Oral melphalan and prednisone chemotherapy plus thalidomide compared with melphalan and prednisone alone in elderly patients with multiple myeloma: randomized controlled trial. Lancet 367: 825–83.CrossRefGoogle Scholar
Palumbo, A, Bringhen, S, Petrucci, MT, et al. 2006. A prospective, randomized, Phase III study of melphalan 200 mg/m2 (MEL200) versus melphalan 100 mg/m2 in newly diagnosed myeloma patients. Blood 108: abstract 55.Google Scholar
Palumbo, A, Bringhen, S, Petrucci, MT, et al. 2004. Intermediate-dose melphalan improves survival of myeloma patients aged 50 to 70: results of a randomized controlled trial. Blood 104: 3052–57.CrossRefGoogle ScholarPubMed
Palumbo, A, Falco, P, Corradini, P, et al. 2007. Melphalan, prednisone, and lenalidomide treatment for newly diagnosed myeloma: a report from the GIMEMA-Italian multiple myeloma network. J Clin Oncol 25: 4459–65.CrossRefGoogle Scholar
Pineda-Roman, M, Tricot, G. 2007. High-dose therapy in patients with plasma cell dyscrasias and renal dysfunction. Contrib Nephrol 153: 182–94.CrossRefGoogle ScholarPubMed
Segeren, CM, Sonneveld, P, Holt, B, Vellenga, E, Croockewit, AJ. 2003. Overall and event-free survival are not improved by the use of myeloablative therapy following intensified chemotherapy in previously untreated patients with multiple myeloma: a prospective randomized phase 3 study. Blood 101: 2144–51.CrossRefGoogle Scholar

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