The special circumstances of plant protection in tropical developing countries, particularly in Africa, are considered within the context of the needs of the preponderant rural farming community, and in respect of food production. The problems are exacerbated by the existence of complex cropping systems (intercropping), the abundance and diversity of pests, the meagre knowledge of the plant-host-pest relationships, and the poor availability of the scientific understanding of the components of pest control and inputs essential for integrated pest management. Institutional innovations, including stepped-up professional training of experts in the field of plant protection, are required to usher in a more sustained effort in efficacious plant protection in these regions. Attempts in this direction are briefly discussed.