Perishable artifacts are invaluable tools for reconstructing past lifeways of hunter-gatherers, and when preserved in arid settings, they can inform on dynamic interactions between communities and the environment. Many such materials were recovered from early archaeological surveys in Utah and Nevada but were largely excluded from contemporary analyses because of small sample sizes, their fragmentary nature, and insecure proveniences. This synchronic reanalysis of cordage and coiled basketry from 10 late Holocene sites in the Great Salt Lake Desert utilizes newer approaches to perishables analysis so as to collect data more conducive to statistical comparisons of subsistence and craft traditions absent from earlier Great Basin studies. Regional trends of conformity of fine cordage contrasted with a diversity of basketry manufacture suggest contemporaneous social stressors directing the production of materials and two potentially gendered subclasses of utilitarian objects. Feminine and masculine perishable crafts in the Bonneville Basin follow separate manufacturing traditions, observable despite small sample sizes and poor dating of these curated collections.

Increases in bed net coverage and antimalarial treatment have reduced the risk of malaria in sub-Saharan Africa. However, the pace of reduction has slowed, and new tools are needed to reverse this trend. We evaluated houses screened with insecticide-treated ceiling nets using a cluster randomized-controlled trial in western Kenya. The primary endpoints were Plasmodium falciparum PCR-positive prevalence (PCRPfPR) of children from 7 months to 10 years old and anopheline density. Ceiling nets and bed nets were provided to 1073 houses, and 1162 houses were provided with bed nets only. The treatment and control arms each had four clusters. We conducted three epidemiological and entomological post-intervention surveys over the course of a year and a half. Each epidemiological survey targeted 150 children per cluster, and entomological surveys targeted 25 houses. When the three surveys were combined, the median PCRPfPRs were 23% (IQR 8%) in the intervention arm and 42% (IQR 12%) in the control arm. The adjusted risk ratio (RR) was 0.53 [95% confidence interval (CI) 0.41–0.71; P = 0.029]. The median anopheline densities were 0.4 (IQR 0.4) and 2.0 (IQR 1.4), respectively. The adjusted RR was 0.41 (95% CI 0.29–0.90; P = 0.029). The present study indicates additional protection from insecticide-screened ceilings over the current best practice.

The RemoveDEBRIS mission has been the first mission to successfully demonstrate, in-orbit, a series of technologies that can be used for the active removal of space debris. The mission started late in 2014 and was sponsored by a grant from the EC that saw a consortium led by the Surrey Space Centre to develop the mission, from concept to in-orbit demonstrations, that terminated in March 2019. Technologies for the capture of large space debris, like a net and a harpoon, have been successfully tested together with hardware and software to retrieve data on non-cooperative target debris kinematics from observations carried out with on board cameras. The final demonstration consisted of the deployment of a drag-sail to increase the drag of the satellite to accelerate its demise.

After summarizing from previous papers the definitions of the concepts associated with nets, i.e. triples of 6-transpositions in the Monster up to braiding, we give some results.

We show that a line arrangement in the complex projective plane supports a nontrivial resonance variety if and only if it is the underlying arrangement of a ‘multinet’, a multi-arrangement with a partition into three or more equinumerous classes which have equal multiplicities at each inter-class intersection point, and satisfy a connectivity condition. We also prove that this combinatorial structure is equivalent to the existence of a pencil of plane curves, also satisfying a connectivity condition, whose singular fibers include at least three products of lines, which comprise the arrangement. We derive numerical conditions which impose restrictions on the number of classes, and the line and point multiplicities that can appear in multinets, and allow us to detect whether the associated pencils yield nonlinear fiberings of the complement.

The norepinephrine transporter (NET) has a major role in terminating the neurochemical signal established by the neurotransmitter norepinephrine (NE) in the synaptic cleft. The NET is also the initial site of action for therapeutic antidepressants, and drugs such as cocaine and amphetamines. Polymorphisms in the NET gene have been identified, and associations with several disorders such as depression have been proposed but not established. However, evidence of a direct association between a genetic mutation of the NET and an autonomic clinical syndrome has recently emerged. A patient and her identical twin were evaluated for typical symptoms of orthostatic intolerance (OI), a disorder mainly characterised by elevated heart rate on standing, and both were found to have clinical and laboratory signs of abnormal uptake of NE. Sequence analysis of the patients' NET gene identified a mutation that resulted in more than 98% loss of function as compared with the wild-type gene. This article reconsiders the important role of the NET protein in the regulation of the nervous and cardiovascular systems, reviews the literature for its polymorphisms and their suggested clinical manifestations, and finally focuses on the effects of its defect on the pathophysiology of OI, the only confirmed direct association between a genetic mutation of the NET and a clinical syndrome.