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1 results

  • 9 - Nanodelivery of Therapeutic Genes

  • James F. Leary, Purdue University, Indiana
  • Book:
    Fundamentals of Nanomedicine
    Published online:
    08 March 2022
    Print publication:
    31 March 2022, pp 159-185

  • Summary

    Typically, there is an optimal dose for treating a diseased cell. But most conventional drug delivery systems have either exponential or biexponential decay characteristics. So-called timed-release drugs create a sawtooth drug delivery pattern, which is a big improvement but still less than optimal. What we really want is to be able to hold the drug delivery to as close to the optimal dose as possible over time. This can best be done using nanomedical systems with biosensing and feedback control systems.