Water is often referred to as our most precious resource, and for a good reason – drinking water and wastewater services sustain core functions of the critical infrastructure, communities, and human life itself. Our water systems are threatened by aging infrastructure, floods, drought, storms, earthquakes, sea level rise, population growth, cyber-security breaches, and pollution, often in combination. Marginalized communities inevitably feel the worst impacts, and our response continues to be hampered by fragmented and antiquated governance and management practices. This paper focuses on the resilience of water sector (drinking water, wastewater, and stormwater [DWS]) to three major hazards (Sea-Level Rise, Earthquake, and Cyberattack). The purpose of this paper is to provide information useful for creating and maintaining resilient water system services. The term resilience describes the ability to adapt to changing conditions and to withstand and recover from disruptions. The resilience of DWS systems is of utmost importance to modern societies that are highly dependent on continued access to these water sector services. This review covers the terminology on water sector resilience and the assessment of a broad landscape of threats mapped with the proposed framework. A more detailed discussion on two areas of resilience is given: Physical Resilience, which is currently a major factor influencing disruptions and failures in DWS systems, and Digital Resilience, which is a rapidly increasing concern for modern infrastructure systems. The resilience of DWS systems should be considered holistically, inclusive of social, digital, and physical systems. The framework integrates various perspectives on water system threats by showcasing interactions between the parts of the DWS systems and their environment. While the challenges of change, shock and stresses are inevitable, embracing a social–ecological–technical system-of-systems and whole-life approach will allow us to better understand and operationalize resilience.