Preplant applications of two 2,4-D formulations and dicamba were evaluated for injury to no-till soybean. Herbicides applied 28 or 21 d before planting (DBP) at 0.56 kg ae/ha for the 2,4-D formulations and 0.28 kg ae/ha for dicamba did not injure soybean. At 14 DBP soybean injury was lower (< 6%) with applications of 2,4-D than with dicamba (13% to 17%). Injury increased when herbicides were applied at 7 DBP with soybean injury from both 2,4-D (< 11%) and dicamba (< 38%). When the herbicides were applied at planting soybean injury was < 18% with the 2,4-D formulations and < 73% with dicamba. Soybean yields were unaffected by the injury from herbicides applied 21, 14, and 7 DBP. However, soybean yield was decreased to 870 kg/ha in 2005 when dicamba was applied at planting compared to the nontreated check (1,950 kg/ha)