This study explores how higher temperatures influence corn yield response to planting density. Using 1990–2010 field trial data from Wisconsin and econometric models with a variety of specifications, we find that higher temperatures reduce the yield benefits of increasing planting density. However, these adverse high-temperature effects are smaller for genetically modified corn varieties, especially those with rootworm-resistant traits. Consistent with previous studies, these results support the notion that varietal improvements through genetic modification may have paved the way for higher planting densities in US corn production. Moreover, our results imply that expected in-season temperatures are important considerations when making planting density decisions.