Field experiments were conducted to evaluate the tolerance of 79 winter wheat cultivars to cyanazine, BAY SMY 1500, and metribuzin. When known, the pedigree of the more cyanazineand BAY SMY 1500-tolerant hard red winter cultivars included ‘Hope’ and/or ‘Cheyenne’ parentage. However, the cultivars more sensitive to BAY SMY 1500, notably those with ‘Vona’ parentage, were not consistently sensitive to cyanazine. Visible injury on the hard red and soft red winter cultivars did not consistently indicate yield reductions. The soft red winter cultivars, compared to the hard red winter cultivars, were generally more sensitive to cyanazine than BAY SMY 1500.