A substrate integrated waveguide (SIW) based self-quadruplexing antenna and its design approach in Ku-band (12–18 GHz) is presented in this paper. This consists of splitting of TE220 mode of square-shaped SIW cavity by incorporating the two diagonal arrays of metallic vias. Accordingly, four orthogonal dominant mode triangular shape SIW cavity (DMTC) resonators are formed. This methodology ensures enhanced isolation. To achieve the broadside radiation, the cavity structure is fed using microstrip lines and rectangular slots are loaded on the top layer of each DMTC. The length and position of each rectangular slot being chosen such that quad-resonances are achieved at 13, 13.5, 14.3, and 15 GHz for the respective DMTC. The equivalent circuit model of the proposed design is also developed, and the tuning of each frequency band is analyzed without affecting the others. The proposed antenna is producing high isolation (>28 dB) among all four ports and a unidirectional radiation pattern with a high front-to-back ratio (>26.8 dB).