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7 results

  • The relationship between the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet and metabolic health status in adolescents with overweight and obesity: results from a cross-sectional study in Iran

  • Maryam Khakbaz, Donya Poursalehi, Saeideh Mirzaei, Ali Asadi, Masoumeh Akhlaghi, Parvane Saneei
  • Journal:
    British Journal of Nutrition , First View
    Published online by Cambridge University Press:
    04 November 2024, pp. 1-9
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  • Few studies investigated the association between Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet and metabolic health status, particularly among adolescents. The present study was designed to investigate the association of MIND diet with metabolic health status in Iranian adolescents with overweight/obesity. This cross-sectional study was done among 203 adolescents with overweight/obesity (12–18 years) in Isfahan, Iran. A validated FFQ was applied to collect dietary intakes. Anthropometric indices and blood pressure were also measured by standard procedures. Fasting blood samples were obtained to determine serum insulin, glucose and lipid profile. To categorise participants as being with metabolically healthy overweight/obesity (MHO) or metabolically unhealthy overweight/obesity (MUO), two methods including International Diabetes Federation (IDF) criteria and IDF plus Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) were applied. Participants had a mean age of 13·98 years and 50·2 % of them were girls. In fully adjusted models, participants with highest MIND diet adherence had lower odds of MUO status based on IDF (OR = 0·20; 95 % CI 0·08, 0·51) and IDF/HOMA-IR (OR = 0·22; 95 % CI 0·08, 0·59) criteria. Stratified analyses revealed that this association was stronger among girls and was only significant among individuals with overweight. An inverse association was also found between MIND diet score and odds of hyperglycaemia and insulin resistance (IR). Higher MIND diet adherence was associated with lower odds MUO in adolescents with overweight/obesity. Inverse associations were also found between MIND diet and odds of hyperglycaemia and IR. Future longitudinal prospective studies are necessary to confirm our results.

  • The effects of MIND diet on depression, anxiety, quality of life and metabolic and hormonal status in obese or overweight women with polycystic ovary syndrome: a randomised clinical trial

  • Seyedeh Sarina Kabiri, Zahra Javanbakht, Maryam Zangeneh, Jalal Moludi, Amir Saber, Yahya Salimi, Arash Tandorost, Mahsa Jamalpour
  • Journal:
    British Journal of Nutrition , First View
    Published online by Cambridge University Press:
    28 October 2024, pp. 1-14
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  • Polycystic ovary syndrome (PCOS) is a common hormonal disorder in women of reproductive age, associated with increased risks of metabolic disorders, depression and reduced quality of life. This study examined the impact of the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet on mental health, PCOS-related quality of life (PCOSQ), anthropometric indices, hirsutism, and metabolic/hormonal parameters in women with PCOS. Total of 52 women with PCOS, aged between 18 and 45 years, were randomly assigned to either the low calorie MIND diet group or the control group. Anthropometric data, depression and anxiety scores, serum levels of gonadotropins (luteinizing hormone [LH], follicle-stimulating hormone [FSH]), PCOSQ, and Ferriman-Gallwey score were evaluated before and after the intervention. Outcomes were assessed at baseline and at the end of the 8-week follow-up period. After 8 weeks, the MIND diet significantly reduced depression (β –3·03; 95 % CI: [–5·36, –0·70]; P = 0·011) and anxiety (β –3·54; 95 % CI: [–6·60, –0·49]; P = 0·024) scores compared with the control group. The MIND diet group exhibited significant increases in the emotion (β 0·63; 95 % CI: [0·18, 1·08]; P = 0·007) and body hair (β 0·65; 95 % CI: [0·03, 1·28]; P = 0·04) domains of the PCOSQ compared to the control group. The changes in other parameters did not show significant differences between the two groups. Both the MIND diet and control groups showed improvements in weight and BMI, with a slight advantage for the MIND diet group. These findings suggest that the MIND diet may be beneficial for improving mental health and some aspects of PCOSQ in women with PCOS.

  • 1 - Physician Heal Thyself

  • Daniel Gibbs, Emeritus of Oregon Health and Science University
  • Book:
    Dispatches from the Land of Alzheimer's
    Published online:
    19 January 2024
    Print publication:
    22 February 2024, pp 5-8
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  • Summary

    An email with a black box warning! That’s what I got 11 years ago after Lois and I submitted saliva samples to a DNA testing service. Lois is the family genealogist, and she thought that DNA testing would be helpful in filling in some of the missing branches of our ancestral trees. In addition to lists of DNA relatives, the report included many risk genes for a variety of medical conditions, none of which were present for either of us. However, this locked black box contained two genes of neurological interest. A mutation in the LRRK-2 gene is the most common cause of hereditary Parkinson’s disease, and the APOE-4 allele is the most significant genetic risk factor for late onset Alzheimer’s disease.

  • 22 - The MIND Diet Revisited

  • Daniel Gibbs, Emeritus of Oregon Health and Science University
  • Book:
    Dispatches from the Land of Alzheimer's
    Published online:
    19 January 2024
    Print publication:
    22 February 2024, pp 91-95

  • Summary

    Over the last 10 years or so, there have been an increasing number of studies that generally agree that people who regularly consume a plant-based, Mediterranean-style diet, are less likely to get Alzheimer’s dementia than those who do not. These studies have found nearly the same results in populations from around the world including the USA, Japan, Australia, Greece, and other European countries. The contents of the diets, age of participants, and extent of benefit may differ from study to study, but overall, those participants who follow a Mediterranean-style diet or one of the variants have between 35–50% less chance of getting Alzheimer’s or, in some studies, all-cause dementia.

  • Adherence to the MIND diet is associated with 12-year all-cause mortality in older adults

  • Janie Corley
  • Journal:
    Public Health Nutrition / Volume 25 / Issue 2 / February 2022
    Published online by Cambridge University Press:
    03 September 2020, pp. 358-367
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      • Open access
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  • Objective:

    To prospectively evaluate the association of three dietary patterns: the MIND (Mediterranean-DASH diet intervention for Neurodegenerative Delay) diet; a Mediterranean-type diet and a traditional diet, with all-cause mortality over a 12-year period in an older sample.

    Design:

    A longitudinal birth cohort study. We ascertained dietary patterns using FFQ data at baseline (2004–2007) and mortality using linkage data. Cox regression was used to estimate mortality hazard ratios (HR) with adjustment for confounders.

    Setting:

    The Lothian Birth Cohort 1936 (LBC1936) study in Edinburgh, Scotland.

    Participants:

    Dietary patterns were ascertained in 882 participants, mean age 69·5 (±0·8) years, at baseline. During the 12-year follow-up (to October 2019), 206 deaths occurred.

    Results:

    In the basic-adjusted model, all three dietary patterns were significantly associated with mortality, the MIND diet and Mediterranean-type diet with a lower risk and the traditional diet with a higher risk. In fully adjusted models, MIND diet score was inversely related to all-cause mortality (HR 0·88; 95 % CI 0·79, 0·97) such that the risk of death was reduced by 12 % per unit increase in MIND diet score. Participants in the top compared with the bottom third of MIND diet score had a 37 % lower risk of death (HR 0·63; 95 % CI 0·41, 0·96). No significant associations with the Mediterranean-type or traditional dietary patterns were observed in the final multivariate model.

    Conclusions:

    Our findings suggest that closer adherence to the MIND diet is associated with a significantly lower risk of all-cause mortality, over 12 years of follow-up, and may constitute a valid public health recommendation for prolonged survival.

  • Using the COM-B model to identify barriers and facilitators towards adoption of a diet associated with cognitive function (MIND diet)

  • Deirdre Timlin, Jacqueline M McCormack, Ellen EA Simpson
  • Journal:
    Public Health Nutrition / Volume 24 / Issue 7 / May 2021
    Published online by Cambridge University Press:
    17 August 2020, pp. 1657-1670
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  • Objective:

    The aim of the study was to identify components of the COM-B (capability, opportunity, motivation and behaviour) model that influences behaviour to modify dietary patterns in 40–55-year-olds living in the UK, in order to influence the risk of cognitive decline in later life.

    Design:

    This is a qualitative study using the COM-B model and theoretical domains framework (TDF) to explore beliefs to adopting the Mediterranean-DASH Intervention for Neurodegenerative delay (MIND) diet.

    Setting:

    Northern Ireland.

    Participants:

    Twenty-five participants were recruited onto the study to take part in either a focus group or an interview. Participants were men and women aged between 40 and 55 years. Participants were recruited via email, Facebook and face to face.

    Results:

    Content analysis revealed that the main perceived barriers to the adoption of the MIND diet were time, work environment, taste preference and convenience. The main perceived facilitators reported were improved health, memory, planning and organisation, and access to good quality food.

    Conclusions:

    This study provides insight into the personal, social and environmental factors that participants report as barriers and facilitators to the adoption of the MIND diet among middle-aged adults living in the UK. More barriers to healthy dietary change were found than facilitators. Future interventions that increase capability, opportunity and motivation may be beneficial. The results from this study will be used to design a behaviour change intervention using the subsequent steps from the Behaviour Change Wheel.

  • 33 - The Role of Nutrition in Cognitive Decline

  • from Part V - Later Life and Interventions
  • Edited by Ayanna K. Thomas, Tufts University, Massachusetts, Angela Gutchess, Brandeis University, Massachusetts
  • Book:
    The Cambridge Handbook of Cognitive Aging
    Published online:
    28 May 2020
    Print publication:
    28 May 2020, pp 612-627

  • Summary

    Strong evidence suggests that older adults at risk of cognitive decline benefit from healthy lifestyle strategies to prevent or delay cognitive disorders. In particular, nutrition has been shown to preserve cognitive functions. Nutritional interventions, whether with single nutrients or following dietary patterns, have all shown protective effects against cognitive decline. In particular, higher levels of vitamins C, D, E, K, and the B family were associated with a better cognitive status. Likewise, fruit and vegetable consumption and omega-3 intake were protective against declined cognition. Regarding dietary patterns, the Mediterranean-type diet, DASH, and MIND diets are all positively associated with slower rates of cognitive decline and decreased risk of incident Alzheimer’s disease and dementia. Nevertheless, intervention trials with vitamins or omega-3 supplements have not demonstrated conclusive evidence for preventing cognitive decline in healthy older adults, or for preventing loss or restoring function in patients with mild to moderate decline. Nutritional recommendations for older adults should emphasize dietary intakes of nutrients and food groups following those recommendations, as well as adoption of the Mediterranean, DASH, or MIND diets, in order to decrease risk of cognitive decline.