Field experiments were conducted at three Mississippi locations to evaluate potential antagonism when postemergence graminicides were tank-mixed with CGA-277476 and to determine if the antagonism could be overcome with an increase in graminicide rate. At all locations when the 1X rate of clethodim, fluazifop-P, or quizalofop was tank-mixed with 79 g ai/ ha CGA-277476, johnsongrass, broadleaf signalgrass, and barnyardgrass control was reduced 5 to 30%. When the graminicide rates were increased to 1.5X, antagonism was still present for fluazifop-P and quizalofop. However, 156 g ai/ha clethodim overcame the antagonism when tank-mixed with 79 g/ha CGA-277476 compared to 105 g/ha clethodim. CGA-277476 alone controlled barnyardgrass and broadleaf signalgrass 38 to 63% and johnsongrass 60 to 85%. There were no differences in soybean yields with graminicides applied alone or tank-mixed with CGA-277476.

Field research was conducted at three locations in Mississippi to evaluate CGA-277476 tank mixtures with four broadleaf herbicides for possible improvement of broadleaf weed control. Tank mixtures in this research were typically additive, although some instances of antagonism were noted. Control of morningglory (Ipomoea) species and hemp sesbania (Sesbania exaltata) was not consistently improved by the addition of acifluorfen, chlorimuron, fomesafen, or imazaquin to 59 or 79 g ai/ha CGA-277476. However, when a large population of weeds was present, the addition of acifluorfen, chlorimuron, or fomesafen to 59 or 79 g/ha CGA-277476 improved control over CGA-277476 alone. Prickly sida (Sida spinosa) was not controlled more than 68% with any treatment in this study; however, horse purslane (Trianthema portulacastrum) was controlled at least 90% with either 79 g/ha CGA-277476 alone or tank-mixed with acifluorfen, fomesafen, chlorimuron, or imazaquin. The addition of CGA-277476 to acifluorfen or fomesafen did not improve control over acifluorfen or fomesafen alone on any of the weeds evaluated; however, the addition of CGA-277476 to imazaquin improved hemp sesbania control over imazaquin alone. Tank mixtures did not result in yields greater than CGA-277476 alone in areas with moderate weed pressure, whereas in areas with severe weed pressure, tank mixtures improved soybean (Glycine max) yield over CGA-277476 alone.