According to the mid-term review of the EU White Paper on Transport, short sea shipping is expected to grow at a rate of 59% in metric tonnes, from 2000 to 2020. If we consider that the overall expected growth in freight exchanges is of some 50%, sea transport is one of the most feasible ways to reduce traffic congestion on European roads. High speed vessels are a possible way to compete with road transport on certain routes; however, these ships are highly affected by heavy weather. This paper analyses the weather influence on several short sea shipping routes to be served by fast ships.