Three-dimensional panel models are widely used in empirical analysis. Researchers use various combinations of fixed effects for three-dimensional panels while the correct specification is unknown. When one imposes a parsimonious model and the true model is rich in complexity, the fitted model inevitably incurs the consequences of misspecification including potential bias. When a richly specified model is employed and the true model is parsimonious, then the consequences typically include a poor fit with larger standard errors than necessary. It is therefore useful for researchers to have good model selection techniques that assist in determining the “true” model or a satisfactory approximation. In this light, Lu, Miao, and Su (2021, Econometric Reviews 40, 867–898) propose methods of model selection. We advance this literature by proposing a method of post-selection inference for regression parameters. Despite our use of the lasso technique as the means of model selection, our assumptions allow for many and even all fixed effects to be nonzero. This property is important to avoid a degenerate distribution of fixed effects which often reflect economic sizes of countries in gravity analyses of trade. Using an international trade database, we document evidence that our key assumption of approximately sparse fixed effects is plausibly satisfied for gravity analyses of trade. We also establish the uniform size control over alternative data generating processes of fixed effects. Simulation studies demonstrate that the proposed method is less biased than under-fitting fixed effect estimators, is more efficient than over-fitting fixed effect estimators, and robustly allows for inference that is as accurate as the oracle estimator.