How did the complex relationship between working worlds and urban spaces change in Hamburg in times of de-industrialization? To answer this question, I focus on Hamburg's history from 1960 to 2008. Starting from the idea of a cumulative structural break, I develop a typology of Fordist and neo-liberal urban spaces and distinguish seven dimensions of change: from international division of labour to globalization, from industrial production to creativity, from rationalization to digitalization, from centralization to networks, from functional zoning to blurred boundaries, from social security to precarity and from suburbanization to the renaissance of the inner city. Finally, I consider whether this typology is valid for other European cities.