Background. Little is known about the interaction of life events with prodromal symptoms in
bulimia nervosa.
Methods. A semistructured research interview based on Paykel's Interview for Recent Life Events
and on the Clinical Interview for Depression for eliciting prodromal symptoms was administered
to 30 patients with bulimia nervosa and 30 healthy control subjects matched for sociodemographic
variables.
Results. Patients reported significantly more stressful life events than controls. Most of the patients
reported prodromal symptoms. Anorexia, low self-esteem, depressed mood, anhedonia, generalized
anxiety and irritability were the most common prodromal symptoms.
Conclusions. The prodromal phase of bulimia nervosa was found to be characterized by a
combination of prodromal symptoms of affective type and stressful life events. Their joint
occurrence may increase vulnerability to bulimia nervosa.