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Schistosoma mansoni: host antigen occurrence on worms recovered from laboratory vertebrate animals

Published online by Cambridge University Press:  06 April 2009

P. M. Z. Coelho ,
G. Gazzinelli  and
J. Pellegrino
P. M. Z. Coelho
Affiliation:
Schistosomiasis Research Unit and Department of Parasitology, Institute of Biological Sciences, Federal University of Minas Gerais, C.P. 2486, 30.000 Belo Horizonte, Brazil; ‘Centro de Pesquisas René Rachou’, INERu-FIOCRUZ, Belo Horizonte, Brazil
G. Gazzinelli
Affiliation:
Schistosomiasis Research Unit and Department of Parasitology, Institute of Biological Sciences, Federal University of Minas Gerais, C.P. 2486, 30.000 Belo Horizonte, Brazil; ‘Centro de Pesquisas René Rachou’, INERu-FIOCRUZ, Belo Horizonte, Brazil
J. Pellegrino
Affiliation:
Schistosomiasis Research Unit and Department of Parasitology, Institute of Biological Sciences, Federal University of Minas Gerais, C.P. 2486, 30.000 Belo Horizonte, Brazil; ‘Centro de Pesquisas René Rachou’, INERu-FIOCRUZ, Belo Horizonte, Brazil
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Summary

By transferring Schistosoma mansoni (12 to 14-day-old worms) from one host into the peritoneal cavity of a host of a different species, it was possible to demonstrate that worms grown in rats, hamsters, Mastomys natalensis and Cebus monkeys were rejected by recipient animals previously immunized against red blood cells of the donor hosts. These results suggest that host-like antigens are acquired by S. mansoni in all hosts. The transfer of worms into the peritoneal cavity has proved to be a simple and convenient method for studying the presence of host antigens in S. mansoni.

Type
Research Article
Information
Parasitology , Volume 81 , Issue 2 , October 1980 , pp. 349 - 354
Copyright
Copyright © Cambridge University Press 1980

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